{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T04:14:42Z","timestamp":1749701682736,"version":"3.41.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,11]]},"DOI":"10.7759\/cureus.85796","type":"journal-article","created":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T20:20:36Z","timestamp":1749673236000},"source":"Crossref","is-referenced-by-count":0,"title":["Radiotherapy for Symptomatic Knuckle Pads Associated With Dupuytren\u2019s Disease: A Report of a Case Series"],"prefix":"10.7759","author":[{"given":"Amanda","family":"Stark","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasamin","family":"Sharifzadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenna","family":"Kahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"Schuster","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Weiss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.4081\/dr.2021.9072","article-title":"Successful treatment of idiopathic knuckle pads with a combination of high-dose salicylic acid and urea topical keratolytics: a case report","volume":"13","author":"Sogliani D","year":"2021","unstructured":"Sogliani D, Mura C, Tamborrini G. Successful treatment of idiopathic knuckle pads with a combination of high-dose salicylic acid and urea topical keratolytics: a case report. Dermatol Rep. 2021, 13:9072. 10.4081\/dr.2021.9072","journal-title":"Dermatol Rep"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/0266-7681(91)90049-t","article-title":"Epidemiological and structural findings supporting the fibromatous origin of dorsal knuckle pads","volume":"16","author":"Caroli A","year":"1991","unstructured":"Caroli A, Zanasi S, Marcuzzi A, Guerra D, Cristiani G, Ronchetti IP. Epidemiological and structural findings supporting the fibromatous origin of dorsal knuckle pads. J Hand Surg Br. 1991, 16:258-62. 10.1016\/0266-7681(91)90049-t","journal-title":"J Hand Surg Br"},{"key":"ref3","article-title":"On an unusual form of nodule upon the joints of the fingers","volume":"29","author":"Garrod AE","year":"1893","unstructured":"Garrod AE. On an unusual form of nodule upon the joints of the fingers. BMJ. 1893, 29:157-61.","journal-title":"BMJ"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/s0363-5023(82)80149-4","article-title":"Dorsal Dupuytren's disease","volume":"7","author":"Hueston JT","year":"1982","unstructured":"Hueston JT. Dorsal Dupuytren's disease. J Hand Surg Am. 1982, 7:384-7. 10.1016\/s0363-5023(82)80149-4","journal-title":"J Hand Surg Am"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/s0072-968x(77)80121-6","article-title":"Knuckle pads in Dupuytren's disease","volume":"9","author":"Mikkelsen A","year":"1977","unstructured":"Mikkelsen A. Knuckle pads in Dupuytren's disease. Hand. 1977, 9:301-5. 10.1016\/s0072-968x(77)80121-6","journal-title":"Hand"},{"key":"ref6","article-title":"Dupuytren\u2019s Disease and Related Hyperproliferative Disorders: Principles, Research, and Clinical Perspectives","author":"Eaton C","year":"2012","unstructured":"Eaton C, Seegenschmiedt MH, Bayat A, Gabbiani G, Werker P, Wach W. Dupuytren\u2019s Disease and Related Hyperproliferative Disorders: Principles, Research, and Clinical Perspectives. Springer Verlag, Heidelberg; 2012."},{"key":"ref7","article-title":"Soft-tissue tumors of the sole; with special reference to plantar fibromatosis","volume":"37-A","author":"Allen RA","year":"1955","unstructured":"Allen RA, Woolner LB, Ghormley RK. Soft-tissue tumors of the sole; with special reference to plantar fibromatosis. J Bone Joint Surg Am. 1955, 37-A:14-26.","journal-title":"J Bone Joint Surg Am"},{"key":"ref8","article-title":"Plantar fibromatosis","volume":"69","author":"Aviles E","year":"1971","unstructured":"Aviles E, Arlen M, Miller T. Plantar fibromatosis. Surgery. 1971, 69:117-20.","journal-title":"Surgery"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s00066-010-2063-z","article-title":"Radiotherapy in early-stage Dupuytren's contracture. Long-term results after 13 years","volume":"186","author":"Betz N","year":"2010","unstructured":"Betz N, Ott OJ, Adamietz B, Sauer R, Fietkau R, Keilholz L. Radiotherapy in early-stage Dupuytren's contracture. Long-term results after 13 years. Strahlenther Onkol. 2010, 186:82-90. 10.1007\/s00066-010-2063-z","journal-title":"Strahlenther Onkol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2010.06.001","article-title":"Dorsal pads versus nodules in normal population and Dupuytren's disease patients","volume":"35","author":"Rayan GM","year":"2010","unstructured":"Rayan GM, Ali M, Orozco J. Dorsal pads versus nodules in normal population and Dupuytren's disease patients. J Hand Surg Am. 2010, 35:1571-9. 10.1016\/j.jhsa.2010.06.001","journal-title":"J Hand Surg Am"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/s0360-3016(00)00745-8","article-title":"Radiotherapy optimization in early-stage Dupuytren\u2019s contracture: first results of a randomized clinical study","volume":"49","author":"Seegenschmiedt MH","year":"2001","unstructured":"Seegenschmiedt MH, Olschewski T, Guntrum F. Radiotherapy optimization in early-stage Dupuytren\u2019s contracture: first results of a randomized clinical study. Int J Radiat Oncol Biol Phys. 2001, 49:785-98. 10.1016\/s0360-3016(00)00745-8","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12711","article-title":"Radiotherapy with soft X-rays in Dupuytren's disease - successful, well-tolerated and satisfying","volume":"29","author":"Zirbs M","year":"2015","unstructured":"Zirbs M, Anzeneder T, Bruckbauer H, Hofmann H, Brockow K, Ring J, Eberlein B. Radiotherapy with soft X-rays in Dupuytren's disease - successful, well-tolerated and satisfying. J Eur Acad Dermatol Venereol. 2015, 29:904-11. 10.1111\/jdv.12711","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsb.2004.06.004","article-title":"An objective method to evaluate the risk of recurrence and extension of Dupuytren's disease","volume":"29","author":"Abe Y","year":"2004","unstructured":"Abe Y, Rokkaku T, Ofuchi S, Tokunaga S, Takahashi K, Moriya H. An objective method to evaluate the risk of recurrence and extension of Dupuytren's disease. J Hand Surg Br. 2004, 29:427-30. 10.1016\/j.jhsb.2004.06.004","journal-title":"J Hand Surg Br"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.66B1.6693470","article-title":"Knuckle pads causing extensor tendon tethering","volume":"66","author":"Addison A","year":"1984","unstructured":"Addison A. Knuckle pads causing extensor tendon tethering. J Bone Joint Surg Br. 1984, 66:128-30. 10.1302\/0301-620X.66B1.6693470","journal-title":"J Bone Joint Surg Br"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/0266-7681(84)90022-6","article-title":"Some observations on knuckle pads","volume":"9","author":"Hueston JT","year":"1984","unstructured":"Hueston JT. Some observations on knuckle pads. J Hand Surg Br. 1984, 9:75-8. 10.1016\/0266-7681(84)90022-6","journal-title":"J Hand Surg Br"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.15557\/JoU.2012.0037","article-title":"Knuckle pads - a rare finding","volume":"12","author":"Tamborrini G","year":"2012","unstructured":"Tamborrini G, Gengenbacher M, Bianchi S. Knuckle pads - a rare finding. J Ultrason. 2012, 12:493-8. 10.15557\/JoU.2012.0037","journal-title":"J Ultrason"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-006-0110-8","article-title":"Ultrasound appearance of knuckle pads","volume":"35","author":"Lopez-Ben R","year":"2006","unstructured":"Lopez-Ben R, Dehghanpisheh K, Chatham WW, Lee DH, Oakes J, Alarc\u00f3n GS. Ultrasound appearance of knuckle pads. Skeletal Radiol. 2006, 35:823-7. 10.1007\/s00256-006-0110-8","journal-title":"Skeletal Radiol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1515\/jim-2017-0044","article-title":"Knuckle pads - practical diagnostic issues","volume":"2","author":"Chiriac A","year":"2017","unstructured":"Chiriac A, Brzezinski P, Foia L, Podoleanu C, Moldovan C, Stolnicu S. Knuckle pads - practical diagnostic issues. J Interdiscip Med. 2017, 2:171-4. 10.1515\/jim-2017-0044","journal-title":"J Interdiscip Med"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.5070\/D3195018177","article-title":"Report of a family with idiopathic knuckle pads and review of idiopathic and disease-associated knuckle pads","volume":"19","author":"Hyman CH","year":"2013","unstructured":"Hyman CH, Cohen PR. Report of a family with idiopathic knuckle pads and review of idiopathic and disease-associated knuckle pads. Dermatol Online J. 2013, 19:18177. 10.5070\/D3195018177","journal-title":"Dermatol Online J"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1063\/1.3453778","article-title":"Knuckle pads---a common problem but good to treat by laser","volume":"1226","author":"Herold M","year":"2009","unstructured":"Herold M, Russe-Wilflingseder K. Knuckle pads---a common problem but good to treat by laser. AIP Conf Proc. 2009, 1226:179-83. 10.1063\/1.3453778","journal-title":"AIP Conf Proc"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1955.01540270061007","article-title":"Discrete keratodermas over the knuckle and finger articulations","volume":"71","author":"Morginson WJ","year":"1955","unstructured":"Morginson WJ. Discrete keratodermas over the knuckle and finger articulations. AMA Arch Derm. 1955, 71:349-53. 10.1001\/archderm.1955.01540270061007","journal-title":"AMA Arch Derm"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1986.02140230085039","article-title":"Knuckle pads in children","volume":"140","author":"Paller AS","year":"1986","unstructured":"Paller AS, Hebert AA. Knuckle pads in children. Am J Dis Child. 1986, 140:915-7. 10.1001\/archpedi.1986.02140230085039","journal-title":"Am J Dis Child"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S414268","article-title":"Knuckle pads successfully treated with 2% crisaborole ointment combined with triamcinolone acetonide and neomycin plaster: a case report","volume":"16","author":"Liang Y","year":"2023","unstructured":"Liang Y, Liang J, Huang Q, Tian X, Shao L, Xia M, Liu Y. Knuckle pads successfully treated with 2% crisaborole ointment combined with triamcinolone acetonide and neomycin plaster: a case report. Clin Cosmet Investig Dermatol. 2023, 16:1893-7. 10.2147\/CCID.S414268","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13803","article-title":"A novel treatment for idiopathic knuckle pads with cantharidin-podophylotoxin-salicylic acid","volume":"36","author":"Hasb\u00fan C","year":"2019","unstructured":"Hasb\u00fan C, Sandoval M, Curi M. A novel treatment for idiopathic knuckle pads with cantharidin-podophylotoxin-salicylic acid. Pediatr Dermatol. 2019, 36:544-5. 10.1111\/pde.13803","journal-title":"Pediatr Dermatol"},{"key":"ref25","article-title":"Knuckle pads","volume":"93","author":"Allison JR Jr","year":"1966","unstructured":"Allison JR Jr, Allison JR Sr. Knuckle pads. Arch Dermatol. 1966, 93:311-6.","journal-title":"Arch Dermatol"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.143.11.1458","article-title":"A novel treatment for knuckle pads with intralesional fluorouracil","volume":"143","author":"Weiss E","year":"2007","unstructured":"Weiss E, Amini S. A novel treatment for knuckle pads with intralesional fluorouracil. Arch Dermatol. 2007, 143:1458-60. 10.1001\/archderm.143.11.1458","journal-title":"Arch Dermatol"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2023.109718","article-title":"Radiotherapy for Ledderhose disease: results of the LedRad-study, a prospective multicentre randomised double-blind phase 3 trial","volume":"185","author":"de Haan A","year":"2023","unstructured":"de Haan A, van Nes JG, Kolff MW, et al.. Radiotherapy for Ledderhose disease: results of the LedRad-study, a prospective multicentre randomised double-blind phase 3 trial. Radiother Oncol. 2023, 185:109718. 10.1016\/j.radonc.2023.109718","journal-title":"Radiother Oncol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/367068-radiotherapy-for-symptomatic-knuckle-pads-associated-with-dupuytrens-disease-a-report-of-a-case-series","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T20:20:37Z","timestamp":1749673237000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/367068-radiotherapy-for-symptomatic-knuckle-pads-associated-with-dupuytrens-disease-a-report-of-a-case-series"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,11]]},"references-count":27,"URL":"https:\/\/doi.org\/10.7759\/cureus.85796","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6,11]]}}}