{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T04:03:28Z","timestamp":1750997008575,"version":"3.41.0"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,25]]},"DOI":"10.7759\/cureus.86774","type":"journal-article","created":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T06:25:33Z","timestamp":1750919133000},"source":"Crossref","is-referenced-by-count":0,"title":["Progressive Pulmonary Lesion due to Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction: A Case Study From Japan"],"prefix":"10.7759","author":[{"given":"Kouko","family":"Hidaka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichrou","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miyuki","family":"Nakakuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Naruse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Ishiguro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/s10038-023-01160-2","article-title":"Clinical and genetic features of cystic fibrosis in Japan","volume":"68","author":"Kozawa Y","year":"2023","unstructured":"Kozawa Y, Yamamoto A, Nakakuki M, et al.. Clinical and genetic features of cystic fibrosis in Japan. J Hum Genet. 2023, 68:671-80. 10.1038\/s10038-023-01160-2","journal-title":"J Hum Genet"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2016.09.064","article-title":"Diagnosis of cystic fibrosis: consensus guidelines from the Cystic Fibrosis Foundation","volume":"181S","author":"Farrell PM","year":"2017","unstructured":"Farrell PM, White TB, Ren CL, et al.. Diagnosis of cystic fibrosis: consensus guidelines from the Cystic Fibrosis Foundation. J Pediatr. 2017, 181S:S4-S15.e1. 10.1016\/j.jpeds.2016.09.064","journal-title":"J Pediatr"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200705-664OC","article-title":"Cystic fibrosis pulmonary guidelines: chronic medications for maintenance of lung health","volume":"176","author":"Flume PA","year":"2007","unstructured":"Flume PA, O'Sullivan BP, Robinson KA, et al.. Cystic fibrosis pulmonary guidelines: chronic medications for maintenance of lung health. Am J Respir Crit Care Med. 2007, 176:957-69. 10.1164\/rccm.200705-664OC","journal-title":"Am J Respir Crit Care Med"},{"key":"ref4","article-title":"Cystic fibrosis [Article in Japanese]","volume":"45","author":"Ishiguro H","year":"2024","unstructured":"Ishiguro H, Fujiki K, Nakakuki M, et al.. Cystic fibrosis [Article in Japanese]. Koky\u016bkinaika. 2024, 45:391-7.","journal-title":"Koky\u016bkinaika"},{"key":"ref5","doi-asserted-by":"crossref","DOI":"10.1097\/01.GIM.0000139505.06194.39","article-title":"Clinical sensitivity of prenatal screening for cystic fibrosis via CFTR carrier testing in a United States panethnic population","volume":"6","author":"Palomaki GE","year":"2004","unstructured":"Palomaki GE, FitzSimmons SC, Haddow JE. Clinical sensitivity of prenatal screening for cystic fibrosis via CFTR carrier testing in a United States panethnic population. Genet Med. 2004, 6:405-14.","journal-title":"Genet Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2543","article-title":"Role of cystic fibrosis transmembrane conductance regulator in patients with chronic sinopulmonary disease","volume":"142","author":"Gonska T","year":"2012","unstructured":"Gonska T, Choi P, Stephenson A, et al.. Role of cystic fibrosis transmembrane conductance regulator in patients with chronic sinopulmonary disease. Chest. 2012, 142:996-1004. 10.1378\/chest.11-2543","journal-title":"Chest"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jped.2018.04.005","article-title":"Chloride and sodium ion concentrations in saliva and sweat as a method to diagnose cystic fibrosis","volume":"95","author":"Gon\u00e7alves AC","year":"2019","unstructured":"Gon\u00e7alves AC, Marson FA, Mendon\u00e7a RM, et al.. Chloride and sodium ion concentrations in saliva and sweat as a method to diagnose cystic fibrosis. J Pediatr (Rio J). 2019, 95:443-50. 10.1016\/j.jped.2018.04.005","journal-title":"J Pediatr (Rio J)"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038\/jhg.2012.46","article-title":"Detection of a large heterozygous deletion and a splicing defect in the CFTR transcripts from nasal swab of a Japanese case of cystic fibrosis","volume":"57","author":"Nakakuki M","year":"2012","unstructured":"Nakakuki M, Fujiki K, Yamamoto A, et al.. Detection of a large heterozygous deletion and a splicing defect in the CFTR transcripts from nasal swab of a Japanese case of cystic fibrosis. J Hum Genet. 2012, 57:427-33. 10.1038\/jhg.2012.46","journal-title":"J Hum Genet"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2003.014456","article-title":"Genetic evidence for CFTR dysfunction in Japanese: background for chronic pancreatitis","volume":"41","author":"Fujiki K","year":"2004","unstructured":"Fujiki K, Ishiguro H, Ko SB, et al.. Genetic evidence for CFTR dysfunction in Japanese: background for chronic pancreatitis. J Med Genet. 2004, 41:e55. 10.1136\/jmg.2003.014456","journal-title":"J Med Genet"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s004390100467","article-title":"CFTR gene mutations--including three novel nucleotide substitutions--and haplotype background in patients with asthma, disseminated bronchiectasis and chronic obstructive pulmonary disease","volume":"108","author":"Tzetis M","year":"2001","unstructured":"Tzetis M, Efthymiadou A, Strofalis S, et al.. CFTR gene mutations--including three novel nucleotide substitutions--and haplotype background in patients with asthma, disseminated bronchiectasis and chronic obstructive pulmonary disease. Hum Genet. 2001, 108:216-21. 10.1007\/s004390100467","journal-title":"Hum Genet"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2019.11.001","article-title":"Genetic variation in CFTR and modifier loci may modulate cystic fibrosis disease severity","volume":"19 Suppl 1","author":"Paranjapye A","year":"2020","unstructured":"Paranjapye A, Ruffin M, Harris A, Corvol H. Genetic variation in CFTR and modifier loci may modulate cystic fibrosis disease severity. J Cyst Fibros. 2020, 19 Suppl 1:S10-4. 10.1016\/j.jcf.2019.11.001","journal-title":"J Cyst Fibros"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.173.1.10397104","article-title":"Evolution of CT findings in patients with cystic fibrosis","volume":"173","author":"Helbich TH","year":"1999","unstructured":"Helbich TH, Heinz-Peer G, Fleischmann D, et al.. Evolution of CT findings in patients with cystic fibrosis. AJR Am J Roentgenol. 1999, 173:81-8. 10.2214\/ajr.173.1.10397104","journal-title":"AJR Am J Roentgenol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/375166-progressive-pulmonary-lesion-due-to-cystic-fibrosis-transmembrane-conductance-regulator-dysfunction-a-case-study-from-japan","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T06:25:34Z","timestamp":1750919134000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/375166-progressive-pulmonary-lesion-due-to-cystic-fibrosis-transmembrane-conductance-regulator-dysfunction-a-case-study-from-japan"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,25]]},"references-count":12,"URL":"https:\/\/doi.org\/10.7759\/cureus.86774","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6,25]]}}}