{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T19:10:04Z","timestamp":1751397004736,"version":"3.41.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,1]]},"DOI":"10.7759\/cureus.87126","type":"journal-article","created":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T18:38:46Z","timestamp":1751395126000},"source":"Crossref","is-referenced-by-count":0,"title":["Lipoprotein Lipase (LPL) Gene Mutation in a Girl With Diabetic Ketoacidosis, Acute Pancreatitis, and Hypertriglyceridemia"],"prefix":"10.7759","author":[{"given":"Duygu","family":"D\u00fczcan Kilimci","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alkan","family":"Bal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferda","family":"Ozkinay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bet\u00fcl","family":"Ersoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.3.6.706","article-title":"Diabetic lipemia in childhood diabetic ketoacidosis: a clue to coexisting acute pancreatitis","volume":"3","author":"Winter RJ","year":"1980","unstructured":"Winter RJ, Herr TJ, Stone NJ, Traisman HS. Diabetic lipemia in childhood diabetic ketoacidosis: a clue to coexisting acute pancreatitis. Diabetes Care. 1980, 3:706-7. 10.2337\/diacare.3.6.706","journal-title":"Diabetes Care"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1515\/jpem.1994.7.3.261","article-title":"Clinical and\/or biochemical pancreatitis in diabetic ketoacidosis","volume":"7","author":"Slyper AH","year":"1994","unstructured":"Slyper AH, Wyatt DT, Brown CW. Clinical and\/or biochemical pancreatitis in diabetic ketoacidosis. J Pediatr Endocrinol. 1994, 7:261-4. 10.1515\/jpem.1994.7.3.261","journal-title":"J Pediatr Endocrinol"},{"key":"ref3","article-title":"Severe hypertriglyceridemia causing acute pancreatitis in a child with new onset type I diabetes mellitus presenting in ketoacidosis","volume":"2","author":"Wolfgram PM","year":"2013","unstructured":"Wolfgram PM, Macdonald MJ. Severe hypertriglyceridemia causing acute pancreatitis in a child with new onset type I diabetes mellitus presenting in ketoacidosis. J Pediatr Intensive Care. 2013, 2:77-80.","journal-title":"J Pediatr Intensive Care"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-200431","article-title":"Acute pancreatitis and severe hypertriglyceridaemia masking unsuspected underlying diabetic ketoacidosis","volume":"2013","author":"Aboulhosn K","year":"2013","unstructured":"Aboulhosn K, Arnason T. Acute pancreatitis and severe hypertriglyceridaemia masking unsuspected underlying diabetic ketoacidosis. BMJ Case Rep. 2013, 2013:10.1136\/bcr-2013-200431","journal-title":"BMJ Case Rep"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.4103\/ijccm.IJCCM_281_16","article-title":"Severe hypertriglyceridemia causing pancreatitis in a child with new-onset type-I diabetes mellitus presenting with diabetic ketoacidosis","volume":"21","author":"Sharma PK","year":"2017","unstructured":"Sharma PK, Kumar M, Yadav DK. Severe hypertriglyceridemia causing pancreatitis in a child with new-onset type-I diabetes mellitus presenting with diabetic ketoacidosis. Indian J Crit Care Med. 2017, 21:176-8. 10.4103\/ijccm.IJCCM_281_16","journal-title":"Indian J Crit Care Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/8974619","article-title":"Diabetic ketoacidosis revealing a severe hypertriglyceridemia and acute pancreatitis in type 1 diabetes mellitus","volume":"2019","author":"Zaher FZ","year":"2019","unstructured":"Zaher FZ, Boubagura I, Rafi S, et al.. Diabetic ketoacidosis revealing a severe hypertriglyceridemia and acute pancreatitis in type 1 diabetes mellitus. Case Rep Endocrinol. 2019, 2019:8974619. 10.1155\/2019\/8974619","journal-title":"Case Rep Endocrinol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/7653730","article-title":"Acute pancreatitis induced by diabetic ketoacidosis with major hypertriglyceridemia: report of four cases","volume":"2020","author":"Bouchaala K","year":"2020","unstructured":"Bouchaala K, Bahloul M, Bradii S, et al.. Acute pancreatitis induced by diabetic ketoacidosis with major hypertriglyceridemia: report of four cases. Case Rep Crit Care. 2020, 2020:7653730. 10.1155\/2020\/7653730","journal-title":"Case Rep Crit Care"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.6065\/apem.2040250.125","article-title":"Hypertriglyceridemia with acute pancreatitis in a 14-year-old girl with diabetic ketoacidosis","volume":"27","author":"Park H","year":"2022","unstructured":"Park H, Kim MS, Kim J, et al.. Hypertriglyceridemia with acute pancreatitis in a 14-year-old girl with diabetic ketoacidosis. Ann Pediatr Endocrinol Metab. 2022, 27:73-7. 10.6065\/apem.2040250.125","journal-title":"Ann Pediatr Endocrinol Metab"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacl.2017.08.017","article-title":"Incidental finding of severe hypertriglyceridemia in children. Role of multiple rare variants in genes affecting plasma triglyceride","volume":"11","author":"Buonuomo PS","year":"2017","unstructured":"Buonuomo PS, Rabacchi C, Macchiaiolo M, et al.. Incidental finding of severe hypertriglyceridemia in children. Role of multiple rare variants in genes affecting plasma triglyceride. J Clin Lipidol. 2017, 11:1329-1337.e3. 10.1016\/j.jacl.2017.08.017","journal-title":"J Clin Lipidol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-3476(74)80353-7","article-title":"Juvenile diabetes and acute pancreatitis","volume":"85(6)","author":"Malone JI","year":"1974","unstructured":"Malone JI. Juvenile diabetes and acute pancreatitis.  J Pediatr. 1974 Dec, 85(6):825-7. 10.1016\/s0022-3476(74)80353-7","journal-title":"J Pediatr"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e318172e99b","article-title":"Elevated serum amylase and lipase in pediatric diabetic ketoacidosis","volume":"9","author":"Quiros JA","year":"2008","unstructured":"Quiros JA, Marcin JP, Kuppermann N, et al.. Elevated serum amylase and lipase in pediatric diabetic ketoacidosis. Pediatr Crit Care Med. 2008, 9:418-22. 10.1097\/PCC.0b013e318172e99b","journal-title":"Pediatr Crit Care Med"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-0217","article-title":"Plasmapheresis to treat hypertriglyceridemia in a child with diabetic ketoacidosis and pancreatitis","volume":"129","author":"Lutfi R","year":"2012","unstructured":"Lutfi R, Huang J, Wong HR. Plasmapheresis to treat hypertriglyceridemia in a child with diabetic ketoacidosis and pancreatitis. Pediatrics. 2012, 129:e195-8. 10.1542\/peds.2011-0217","journal-title":"Pediatrics"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.99.22.2901","article-title":"Lipoprotein lipase mutations, plasma lipids and lipoproteins, and risk of ischemic heart disease. A meta-analysis","volume":"99","author":"Wittrup HH","year":"1999","unstructured":"Wittrup HH, Tybjaerg-Hansen A, Nordestgaard BG. Lipoprotein lipase mutations, plasma lipids and lipoproteins, and risk of ischemic heart disease. A meta-analysis. Circulation. 1999, 99:2901-7. 10.1161\/01.cir.99.22.2901","journal-title":"Circulation"},{"key":"ref14","unstructured":"National Library of Medicine. ClinVar. (2025). Accessed: June 26, 2025: https:\/\/www.ncbi.nlm.nih.gov\/clinvar\/."}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/308328-lipoprotein-lipase-lpl-gene-mutation-in-a-girl-with-diabetic-ketoacidosis-acute-pancreatitis-and-hypertriglyceridemia","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T18:38:47Z","timestamp":1751395127000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/308328-lipoprotein-lipase-lpl-gene-mutation-in-a-girl-with-diabetic-ketoacidosis-acute-pancreatitis-and-hypertriglyceridemia"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,1]]},"references-count":14,"URL":"https:\/\/doi.org\/10.7759\/cureus.87126","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7,1]]}}}