{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:20:04Z","timestamp":1785450004386,"version":"3.56.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,4]]},"DOI":"10.7759\/cureus.87275","type":"journal-article","created":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T11:55:17Z","timestamp":1751630117000},"source":"Crossref","is-referenced-by-count":1,"title":["Cardiac Stereotactic Body Radiation Therapy (SBRT) for Refractory Ventricular Tachycardia Using Innovative Motion Tracking With Electroanatomical Mapping and CyberKnife Synchrony"],"prefix":"10.7759","author":[{"given":"Chaewon","family":"Hwang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gleb A","family":"Kuzmin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Maher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nima","family":"Aghdam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa065457","article-title":"Prophylactic catheter ablation for the prevention of defibrillator therapy","volume":"357","author":"Reddy VY","year":"2007","unstructured":"Reddy VY, Reynolds MR, Neuzil P, et al.. Prophylactic catheter ablation for the prevention of defibrillator therapy. N Engl J Med. 2007, 357:2657-65. 10.1056\/NEJMoa065457","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1513614","article-title":"Ventricular tachycardia ablation versus escalation of antiarrhythmic drugs","volume":"375","author":"Sapp JL","year":"2016","unstructured":"Sapp JL, Wells GA, Parkash R, et al.. Ventricular tachycardia ablation versus escalation of antiarrhythmic drugs. N Engl J Med. 2016, 375:111-21. 10.1056\/NEJMoa1513614","journal-title":"N Engl J Med"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61755-4","article-title":"Catheter ablation of stable ventricular tachycardia before defibrillator implantation in patients with coronary heart disease (VTACH): a multicentre randomised controlled trial","volume":"375","author":"Kuck K\u2010H","year":"2010","unstructured":"Kuck K\u2010H, Schaumann A, Eckardt L, et al.. Catheter ablation of stable ventricular tachycardia before defibrillator implantation in patients with coronary heart disease (VTACH): a multicentre randomised controlled trial. Lancet Lond Engl. 2010, 375:31-40. 10.1016\/S0140-6736(09)61755-4","journal-title":"Lancet Lond Engl"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2016.07.001","article-title":"Long-term outcomes after catheter ablation of ventricular tachycardia in patients with and without structural heart disease","volume":"13","author":"Kumar S","year":"2016","unstructured":"Kumar S, Romero J, Mehta NK, et al.. Long-term outcomes after catheter ablation of ventricular tachycardia in patients with and without structural heart disease. Heart Rhythm. 2016, 13:1957-63. 10.1016\/j.hrthm.2016.07.001","journal-title":"Heart Rhythm"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.116.004422","article-title":"Impact of substrate modification by catheter ablation on implantable cardioverter-defibrillator interventions in patients with unstable ventricular arrhythmias and coronary artery disease: results from the multicenter randomized controlled SMS (substrate modification study)","volume":"10","author":"Kuck KH","year":"2017","unstructured":"Kuck KH, Tilz RR, Deneke T, et al.. Impact of substrate modification by catheter ablation on implantable cardioverter-defibrillator interventions in patients with unstable ventricular arrhythmias and coronary artery disease: results from the multicenter randomized controlled SMS (substrate modification study). Circ Arrhythm Electrophysiol. 2017, 10:004422. 10.1161\/CIRCEP.116.004422","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.115.002765","article-title":"Stereotactic ablative radiotherapy for the treatment of refractory cardiac ventricular arrhythmia","volume":"8","author":"Loo BW Jr","year":"2015","unstructured":"Loo BW Jr, Soltys SG, Wang L, et al.. Stereotactic ablative radiotherapy for the treatment of refractory cardiac ventricular arrhythmia. Circ Arrhythm Electrophysiol. 2015, 8:748-50. 10.1161\/CIRCEP.115.002765","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.190","article-title":"Cardiac radiosurgery for malignant ventricular tachycardia","volume":"6","author":"Cvek J","year":"2014","unstructured":"Cvek J, Neuwirth R, Knybel L, et al.. Cardiac radiosurgery for malignant ventricular tachycardia. Cureus. 2014, 6:190. 10.7759\/cureus.190","journal-title":"Cureus"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/eux161.118","article-title":"Noninvasive cardiac radiosurgery: current clinical experience for treatment of refractory arrhythmias","volume":"19","author":"Zei P","year":"2017","unstructured":"Zei P, Gardner E, Fogarty T, Maguire P. Noninvasive cardiac radiosurgery: current clinical experience for treatment of refractory arrhythmias. EP Eur. 2017, 19:402. 10.1093\/ehjci\/eux161.118","journal-title":"EP Eur"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1613773","article-title":"Noninvasive cardiac radiation for ablation of ventricular tachycardia","volume":"377","author":"Cuculich PS","year":"2017","unstructured":"Cuculich PS, Schill MR, Kashani R, et al.. Noninvasive cardiac radiation for ablation of ventricular tachycardia. N Engl J Med. 2017, 377:2325-36. 10.1056\/NEJMoa1613773","journal-title":"N Engl J Med"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2018.04.025","article-title":"Rescue procedure for an electrical storm using robotic non-invasive cardiac radio-ablation","volume":"128","author":"Jumeau R","year":"2018","unstructured":"Jumeau R, Ozsahin M, Schwitter J, et al.. Rescue procedure for an electrical storm using robotic non-invasive cardiac radio-ablation. Radiother Oncol. 2018, 128:189-91. 10.1016\/j.radonc.2018.04.025","journal-title":"Radiother Oncol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.038261","article-title":"Phase I\/II trial of electrophysiology\u2010guided noninvasive cardiac radioablation for ventricular tachycardia","volume":"139","author":"Robinson CG","year":"2019","unstructured":"Robinson CG, Samson PP, Moore KM, et al.. Phase I\/II trial of electrophysiology\u2010guided noninvasive cardiac radioablation for ventricular tachycardia. Circulation. 2019, 139:313-21. 10.1161\/CIRCULATIONAHA.118.038261","journal-title":"Circulation"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrcr.2018.10.007","article-title":"Stereotactic radiosurgery as a treatment for recurrent ventricular tachycardia associated with cardiac fibroma","volume":"5","author":"Haskova J","year":"2019","unstructured":"Haskova J, Peichl P, Pirk J, Cvek J, Neuwirth R, Kautzner J. Stereotactic radiosurgery as a treatment for recurrent ventricular tachycardia associated with cardiac fibroma. HeartRhythm Case Rep. 2019, 5:44-7. 10.1016\/j.hrcr.2018.10.007","journal-title":"HeartRhythm Case Rep"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/pace.13731","article-title":"Stereotactic body radiation therapy for refractory ventricular tachycardia secondary to cardiac lipoma: a case report","volume":"42","author":"Zeng LJ","year":"2019","unstructured":"Zeng LJ, Huang LH, Tan H, et al.. Stereotactic body radiation therapy for refractory ventricular tachycardia secondary to cardiac lipoma: a case report. Pacing Clin Electrophysiol. 2019, 42:1276-9. 10.1111\/pace.13731","journal-title":"Pacing Clin Electrophysiol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2024.07.029","article-title":"Stereotactic arrhythmia radioablation (STAR)-a systematic review and meta-analysis of prospective trials on behalf of the STOPSTORM.eu consortium","volume":"22","author":"Miszczyk M","year":"2025","unstructured":"Miszczyk M, Hoeksema WF, Kuna K, et al.. Stereotactic arrhythmia radioablation (STAR)-a systematic review and meta-analysis of prospective trials on behalf of the STOPSTORM.eu consortium. Heart Rhythm. 2025, 22:80-9. 10.1016\/j.hrthm.2024.07.029","journal-title":"Heart Rhythm"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2021.12.011","article-title":"2022 AHA\/ACC\/HFSA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology\/American Heart Association Joint Committee on clinical practice guidelines","volume":"79","author":"Heidenreich PA","year":"2022","unstructured":"Heidenreich PA, Bozkurt B, Aguilar D, et al.. 2022 AHA\/ACC\/HFSA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology\/American Heart Association Joint Committee on clinical practice guidelines. J Am Coll Cardiol. 2022, 79:1757-80. 10.1016\/j.jacc.2021.12.011","journal-title":"J Am Coll Cardiol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2015.07.2260","article-title":"A randomized phase 2 study comparing 2 stereotactic body radiation therapy schedules for medically inoperable patients with stage I peripheral non-small cell lung cancer: NRG Oncology RTOG 0915 (NCCTG N0927)","volume":"93","author":"Videtic GM","year":"2015","unstructured":"Videtic GM, Hu C, Singh AK, et al.. A randomized phase 2 study comparing 2 stereotactic body radiation therapy schedules for medically inoperable patients with stage I peripheral non-small cell lung cancer: NRG Oncology RTOG 0915 (NCCTG N0927). Int J Radiat Oncol Biol Phys. 2015, 93:757-64. 10.1016\/j.ijrobp.2015.07.2260","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/jce.15259","article-title":"Cardiac stereotactic body radiation therapy for ventricular tachycardia: current experience and technical gaps","volume":"32","author":"Wei C","year":"2021","unstructured":"Wei C, Qian PC, Boeck M, et al.. Cardiac stereotactic body radiation therapy for ventricular tachycardia: current experience and technical gaps. J Cardiovasc Electrophysiol. 2021, 32:2901-14. 10.1111\/jce.15259","journal-title":"J Cardiovasc Electrophysiol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.124.034814","article-title":"Ten-year outcomes and predictors of mortality following catheter ablation of ventricular tachycardia","volume":"14","author":"Rottner L","year":"2025","unstructured":"Rottner L, Metzner A, Hochadel M, et al.. Ten-year outcomes and predictors of mortality following catheter ablation of ventricular tachycardia. J Am Heart Assoc. 2025, 14:034814. 10.1161\/JAHA.124.034814","journal-title":"J Am Heart Assoc"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2021.02.016","article-title":"Ventricular tachycardia burden reduction after substrate ablation: predictors of recurrence","volume":"18","author":"Quinto L","year":"2021","unstructured":"Quinto L, Sanchez-Somonte P, Alarc\u00f3n F, et al.. Ventricular tachycardia burden reduction after substrate ablation: predictors of recurrence. Heart Rhythm. 2021, 18:896-904. 10.1016\/j.hrthm.2021.02.016","journal-title":"Heart Rhythm"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcm.2023.12.008","article-title":"One-year mortality and causes of death after stereotactic radiation therapy for refractory ventricular arrhythmias: a systematic review and pooled analysis","volume":"34","author":"Benali K","year":"2024","unstructured":"Benali K, Zei PC, Lloyd M, et al.. One-year mortality and causes of death after stereotactic radiation therapy for refractory ventricular arrhythmias: a systematic review and pooled analysis. Trends Cardiovasc Med. 2024, 34:488-96. 10.1016\/j.tcm.2023.12.008","journal-title":"Trends Cardiovasc Med"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euae214","article-title":"Patient selection, ventricular tachycardia substrate delineation, and data transfer for stereotactic arrhythmia radioablation: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology and the Heart Rhythm Society","volume":"27","author":"Zeppenfeld K","year":"2025","unstructured":"Zeppenfeld K, Rademaker R, Al-Ahmad A, et al.. Patient selection, ventricular tachycardia substrate delineation, and data transfer for stereotactic arrhythmia radioablation: a clinical consensus statement of the European Heart Rhythm Association of the European Society of Cardiology and the Heart Rhythm Society. Europace. 2025, 27:214. 10.1093\/europace\/euae214","journal-title":"Europace"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2023.08.059","article-title":"A framework for assessing the effect of cardiac and respiratory motion for stereotactic arrhythmia radioablation using a digital Phantom with a 17-segment model: a Stopstorm.eu consortium study","volume":"118","author":"Stevens RR","year":"2024","unstructured":"Stevens RR, Hazelaar C, Bogowicz M, et al.. A framework for assessing the effect of cardiac and respiratory motion for stereotactic arrhythmia radioablation using a digital Phantom with a 17-segment model: a Stopstorm.eu consortium study. Int J Radiat Oncol Biol Phys. 2024, 118:533-42. 10.1016\/j.ijrobp.2023.08.059","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euad268","article-title":"Recurrences of ventricular tachycardia after stereotactic arrhythmia radioablation arise outside the treated volume: analysis of the Swiss cohort","volume":"25","author":"Herrera Siklody C","year":"2023","unstructured":"Herrera Siklody C, Schiappacasse L, Jumeau R, et al.. Recurrences of ventricular tachycardia after stereotactic arrhythmia radioablation arise outside the treated volume: analysis of the Swiss cohort. Europace. 2023, 25:268. 10.1093\/europace\/euad268","journal-title":"Europace"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-25730-0","article-title":"Cardiac radiotherapy induces electrical conduction reprogramming in the absence of transmural fibrosis","volume":"12","author":"Zhang DM","year":"2021","unstructured":"Zhang DM, Navara R, Yin T, et al.. Cardiac radiotherapy induces electrical conduction reprogramming in the absence of transmural fibrosis. Nat Commun. 2021, 12:5558. 10.1038\/s41467-021-25730-0","journal-title":"Nat Commun"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/368972-cardiac-stereotactic-body-radiation-therapy-sbrt-for-refractory-ventricular-tachycardia-using-innovative-motion-tracking-with-electroanatomical-mapping-and-cyberknife-synchrony","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T11:55:18Z","timestamp":1751630118000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/368972-cardiac-stereotactic-body-radiation-therapy-sbrt-for-refractory-ventricular-tachycardia-using-innovative-motion-tracking-with-electroanatomical-mapping-and-cyberknife-synchrony"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,4]]},"references-count":24,"URL":"https:\/\/doi.org\/10.7759\/cureus.87275","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7,4]]}}}