{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T11:10:07Z","timestamp":1752232207710,"version":"3.41.2"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,11]]},"DOI":"10.7759\/cureus.87717","type":"journal-article","created":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T10:49:16Z","timestamp":1752230956000},"source":"Crossref","is-referenced-by-count":0,"title":["Investigating Factors Related to Length of Hospital Stay in Male Patients With Lung Cancer Undergoing Chemotherapy"],"prefix":"10.7759","author":[{"given":"Takeshi","family":"Yamazaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minami","family":"Tanemura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michiko","family":"Tsuchiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukio","family":"Nagasaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shota","family":"Kotani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shojiro","family":"Egoshi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohji","family":"Iwai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Horie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyv088","article-title":"Cancer incidence and incidence rates in Japan in 2009: a study of 32 population-based cancer registries for the monitoring of cancer incidence in Japan (MCIJ) project","volume":"45","author":"Hori M","year":"2015","unstructured":"Hori M, Matsuda T, Shibata A, Katanoda K, Sobue T, Nishimoto H. Cancer incidence and incidence rates in Japan in 2009: a study of 32 population-based cancer registries for the monitoring of cancer incidence in Japan (MCIJ) project. Jpn J Clin Oncol. 2015, 45:884-91. 10.1093\/jjco\/hyv088","journal-title":"Jpn J Clin Oncol"},{"key":"ref2","unstructured":"[Latest cancer statistics]. (2025). Accessed. July 6, 2025: https:\/\/ganjoho.jp\/reg_stat\/statistics\/stat\/summary.html."},{"key":"ref3","article-title":"[Cancer pharmacotherapy based on geriatric assessment]","volume":"54","author":"Matsuoka A","year":"2016","unstructured":"Matsuoka A, Hayashi N, Ando Y. [Cancer pharmacotherapy based on geriatric assessment]. Ronen Igaku. 2016, 54:1233.","journal-title":"Ronen Igaku"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3109\/02841869009091786","article-title":"Hospitalization during chemotherapy for small cell lung cancer","volume":"29","author":"Bergman B","year":"1990","unstructured":"Bergman B, S\u00f6renson S. Hospitalization during chemotherapy for small cell lung cancer. Acta Oncol. 1990, 29:977-82. 10.3109\/02841869009091786","journal-title":"Acta Oncol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S201873","article-title":"Prediction of chemotherapy adverse reactions and mortality in older patients with primary lung cancer through frailty index based on routine laboratory data","volume":"14","author":"Wang Y","year":"2019","unstructured":"Wang Y, Zhang R, Shen Y, Su L, Dong B, Hao Q. Prediction of chemotherapy adverse reactions and mortality in older patients with primary lung cancer through frailty index based on routine laboratory data. Clin Interv Aging. 2019, 14:1187-97. 10.2147\/CIA.S201873","journal-title":"Clin Interv Aging"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgo.2018.06.007","article-title":"Frailty assessment predicts toxicity during first cycle chemotherapy for advanced lung cancer regardless of chronologic age","volume":"10","author":"Ruiz J","year":"2019","unstructured":"Ruiz J, Miller AA, Tooze JA, Crane S, Petty WJ, Gajra A, Klepin HD. Frailty assessment predicts toxicity during first cycle chemotherapy for advanced lung cancer regardless of chronologic age. J Geriatr Oncol. 2019, 10:48-54. 10.1016\/j.jgo.2018.06.007","journal-title":"J Geriatr Oncol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.18632\/aging.203673","article-title":"Association of frailty and chemotherapy-related adverse outcomes in geriatric patients with cancer: a pilot observational study in Taiwan","volume":"13","author":"Ho YW","year":"2021","unstructured":"Ho YW, Tang WR, Chen SY, Lee SH, Chen JS, Hung YS, Chou WC. Association of frailty and chemotherapy-related adverse outcomes in geriatric patients with cancer: a pilot observational study in Taiwan. Aging (Albany NY). 2021, 13:24192-204. 10.18632\/aging.203673","journal-title":"Aging (Albany NY)"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/s0169-5002(01)00311-7","article-title":"Influence of age and comorbidities on the chemotherapeutic management of lung cancer","volume":"33","author":"Deppermann KM","year":"2001","unstructured":"Deppermann KM. Influence of age and comorbidities on the chemotherapeutic management of lung cancer. Lung Cancer. 2001, 33:S115-20. 10.1016\/s0169-5002(01)00311-7","journal-title":"Lung Cancer"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186\/s40364-017-0091-x","article-title":"Length of hospitalization is associated with selected biomarkers (albumin and lymphocytes) and with co-morbidities: study on 4000 patients","volume":"5","author":"Pontiroli AE","year":"2017","unstructured":"Pontiroli AE, Loreggian L, Rovati MP, et al.. Length of hospitalization is associated with selected biomarkers (albumin and lymphocytes) and with co-morbidities: study on 4000 patients. Biomark Res. 2017, 5:13. 10.1186\/s40364-017-0091-x","journal-title":"Biomark Res"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson ME","year":"1987","unstructured":"Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987, 40:373-83. 10.1016\/0021-9681(87)90171-8","journal-title":"J Chronic Dis"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/00000421-198212000-00014","article-title":"Toxicity and response criteria of the Eastern Cooperative Oncology Group","volume":"5","author":"Oken MM","year":"1982","unstructured":"Oken MM, Creech RH, Tormey DC, Horton J, Davis TE, McFadden ET, Carbone PP. Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol. 1982, 5:649-55. 10.1097\/00000421-198212000-00014","journal-title":"Am J Clin Oncol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/56.3.m146","article-title":"Frailty in older adults: evidence for a phenotype","volume":"56","author":"Fried LP","year":"2001","unstructured":"Fried LP, Tangen CM, Walston J, et al.. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001, 56:M146-56. 10.1093\/gerona\/56.3.m146","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.13129","article-title":"Prevalence of frailty among community-dwellers and outpatients in Japan as defined by the Japanese version of the cardiovascular health study criteria","volume":"17","author":"Satake S","year":"2017","unstructured":"Satake S, Shimada H, Yamada M, et al.. Prevalence of frailty among community-dwellers and outpatients in Japan as defined by the Japanese version of the cardiovascular health study criteria. Geriatr Gerontol Int. 2017, 17:2629-34. 10.1111\/ggi.13129","journal-title":"Geriatr Gerontol Int"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9993(96)90184-7","article-title":"The reliability of the functional independence measure: a quantitative review","volume":"77","author":"Ottenbacher KJ","year":"1996","unstructured":"Ottenbacher KJ, Hsu Y, Granger CV, Fiedler RC. The reliability of the functional independence measure: a quantitative review. Arch Phys Med Rehabil. 1996, 77:1226-32. 10.1016\/S0003-9993(96)90184-7","journal-title":"Arch Phys Med Rehabil"},{"key":"ref15","article-title":"Functional evaluation: the Barthel index","volume":"14","author":"Mahoney FI","year":"1965","unstructured":"Mahoney FI, Barthel DW. Functional evaluation: the Barthel index. Md State Med J. 1965, 14:61-5.","journal-title":"Md State Med J"},{"key":"ref16","unstructured":"Common Terminology Criteria for Adverse Events (CTCAE). (2009). Accessed. July 11, 2025: https:\/\/dctd.cancer.gov\/research\/ctep-trials\/trial-development."},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1200\/OP.20.00681","article-title":"Predictors of unplanned hospitalizations among older adults receiving cancer chemotherapy","volume":"17","author":"Klepin HD","year":"2021","unstructured":"Klepin HD, Sun CL, Smith DD, et al.. Predictors of unplanned hospitalizations among older adults receiving cancer chemotherapy. JCO Oncol Pract. 2021, 17:e740-52. 10.1200\/OP.20.00681","journal-title":"JCO Oncol Pract"},{"key":"ref18","article-title":"Statistical Power Analysis for the Behavioral Sciences, 2nd Edition","author":"Cohen J","year":"1988","unstructured":"Cohen J. Statistical Power Analysis for the Behavioral Sciences, 2nd Edition. Lawrence Erlbaum Associates, New Jersey, US; 1988."},{"key":"ref19","article-title":"Multivariate Data Analysis, 7th Edition","author":"Hair JF","year":"2010","unstructured":"Hair JF, Black WC, Babin BJ, Anderson RE. Multivariate Data Analysis, 7th Edition. Pearson Prentice Hall, New Jersey, US; 2010."},{"key":"ref20","unstructured":"Length of hospital stay. (2025). Accessed. July 6, 2025: https:\/\/www.oecd.org\/en\/data\/indicators\/length-of-hospital-stay.html."},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S247967","article-title":"Prognostic value of pretreatment albumin-to-alkaline phosphatase ratio in extensive-disease small-cell lung cancer: a retrospective cohort study","volume":"12","author":"Zhou S","year":"2020","unstructured":"Zhou S, Wang H, Jiang W, Yu Q, Zeng A. Prognostic value of pretreatment albumin-to-alkaline phosphatase ratio in extensive-disease small-cell lung cancer: a retrospective cohort study. Cancer Manag Res. 2020, 12:2015-24. 10.2147\/CMAR.S247967","journal-title":"Cancer Manag Res"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2023.e19225","article-title":"The prognostic value of pretreatment albumin-to-fibrinogen ratio in small cell lung cancer patients receiving first-line platinum-based chemotherapy","volume":"9","author":"Li Q","year":"2023","unstructured":"Li Q, Li L, Wang Y, Xu C, Zou J. The prognostic value of pretreatment albumin-to-fibrinogen ratio in small cell lung cancer patients receiving first-line platinum-based chemotherapy. Heliyon. 2023, 9:e19225. 10.1016\/j.heliyon.2023.e19225","journal-title":"Heliyon"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-019-01539-2","article-title":"Albumin-globulin ratio is a predictive biomarker of antitumor effect of anti-PD-1 antibody in patients with non-small cell lung cancer","volume":"25","author":"Nakanishi Y","year":"2020","unstructured":"Nakanishi Y, Masuda T, Yamaguchi K, et al.. Albumin-globulin ratio is a predictive biomarker of antitumor effect of anti-PD-1 antibody in patients with non-small cell lung cancer. Int J Clin Oncol. 2020, 25:74-81. 10.1007\/s10147-019-01539-2","journal-title":"Int J Clin Oncol"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000034726","article-title":"The association between albumin and C-reactive protein in older adults","volume":"102","author":"Jiang Y","year":"2023","unstructured":"Jiang Y, Yang Z, Wu Q, Cao J, Qiu T. The association between albumin and C-reactive protein in older adults. Medicine (Baltimore). 2023, 102:e34726. 10.1097\/MD.0000000000034726","journal-title":"Medicine (Baltimore)"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2015.02.009","article-title":"Serum albumin and health in older people: review and meta analysis","volume":"81","author":"Cabrerizo S","year":"2015","unstructured":"Cabrerizo S, Cuadras D, Gomez-Busto F, Artaza-Artabe I, Mar\u00edn-Ciancas F, Malafarina V. Serum albumin and health in older people: review and meta analysis. Maturitas. 2015, 81:17-27. 10.1016\/j.maturitas.2015.02.009","journal-title":"Maturitas"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2891-9-69","article-title":"Pretreatment serum albumin as a predictor of cancer survival: a systematic review of the epidemiological literature","volume":"9","author":"Gupta D","year":"2010","unstructured":"Gupta D, Lis CG. Pretreatment serum albumin as a predictor of cancer survival: a systematic review of the epidemiological literature. Nutr J. 2010, 9:69. 10.1186\/1475-2891-9-69","journal-title":"Nutr J"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v11.i11.1639","article-title":"Serum IL-6, TNFalpha and CRP levels in Greek colorectal cancer patients: prognostic implications","volume":"11","author":"Nikiteas NI","year":"2005","unstructured":"Nikiteas NI, Tzanakis N, Gazouli M, et al.. Serum IL-6, TNFalpha and CRP levels in Greek colorectal cancer patients: prognostic implications. World J Gastroenterol. 2005, 11:1639-43. 10.3748\/wjg.v11.i11.1639","journal-title":"World J Gastroenterol"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9610(98)00204-9","article-title":"Significance of preoperative elevation of serum C-reactive protein as an indicator for prognosis in colorectal cancer","volume":"176","author":"Nozoe T","year":"1998","unstructured":"Nozoe T, Matsumata T, Kitamura M, Sugimachi K. Significance of preoperative elevation of serum C-reactive protein as an indicator for prognosis in colorectal cancer. Am J Surg. 1998, 176:335-8. 10.1016\/s0002-9610(98)00204-9","journal-title":"Am J Surg"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/365860-investigating-factors-related-to-length-of-hospital-stay-in-male-patients-with-lung-cancer-undergoing-chemotherapy","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T10:49:18Z","timestamp":1752230958000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/365860-investigating-factors-related-to-length-of-hospital-stay-in-male-patients-with-lung-cancer-undergoing-chemotherapy"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,11]]},"references-count":28,"URL":"https:\/\/doi.org\/10.7759\/cureus.87717","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7,11]]}}}