{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T19:04:39Z","timestamp":1783191879812,"version":"3.54.6"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,10]]},"DOI":"10.7759\/cureus.89737","type":"journal-article","created":{"date-parts":[[2025,8,10]],"date-time":"2025-08-10T16:40:21Z","timestamp":1754844021000},"source":"Crossref","is-referenced-by-count":2,"title":["Definitive Chemoradiation Followed by Consolidation Immunotherapy for Unresectable Tracheal Squamous Cell Carcinoma: A Case Report"],"prefix":"10.7759","author":[{"given":"Adil","family":"Sayeed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salman","family":"Hasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-006-9229-z","article-title":"Incidence and treatment of tracheal cancer: a nationwide study in the Netherlands","volume":"14","author":"Honings J","year":"2007","unstructured":"Honings J, van Dijck JA, Verhagen AF, et al.. Incidence and treatment of tracheal cancer: a nationwide study in the Netherlands. Ann Surg Oncol. 2007, 14:968-76. 10.1245\/s10434-006-9229-z","journal-title":"Ann Surg Oncol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24123","article-title":"Management and prognosis of primary tracheal cancer: a national analysis","volume":"124","author":"Nouraei SM","year":"2014","unstructured":"Nouraei SM, Middleton SE, Nouraei SA, et al.. Management and prognosis of primary tracheal cancer: a national analysis. Laryngoscope. 2014, 124:145-50. 10.1002\/lary.24123","journal-title":"Laryngoscope"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.thorsurg.2013.10.002","article-title":"Treatment approaches to primary tracheal cancer","volume":"24","author":"Behringer D","year":"2014","unstructured":"Behringer D, K\u00f6nemann S, Hecker E. Treatment approaches to primary tracheal cancer. Thorac Surg Clin. 2014, 24:73-6. 10.1016\/j.thorsurg.2013.10.002","journal-title":"Thorac Surg Clin"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/MCP.0000000000000181","article-title":"Malignant tracheal tumors: a review of current diagnostic and management strategies","volume":"21","author":"Sherani K","year":"2015","unstructured":"Sherani K, Vakil A, Dodhia C, Fein A. Malignant tracheal tumors: a review of current diagnostic and management strategies. Curr Opin Pulm Med. 2015, 21:322-6. 10.1097\/MCP.0000000000000181","journal-title":"Curr Opin Pulm Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19900901)66:5<894::aid-cncr2820660514>3.0.co;2-w","article-title":"Primary malignant tumors of the trachea. A radiologic and clinical study","volume":"66","author":"Li W","year":"1990","unstructured":"Li W, Ellerbroek NA, Libshitz HI. Primary malignant tumors of the trachea. A radiologic and clinical study. Cancer. 1990, 66:894-899. 10.1002\/1097-0142(19900901)66:5&lt;894::aid-cncr2820660514&gt;3.0.co;2-w","journal-title":"Cancer"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0b013e3181cae8ab","article-title":"Population based cancer registry analysis of primary tracheal carcinoma","volume":"34","author":"Urdaneta AI","year":"2011","unstructured":"Urdaneta AI, Yu JB, Wilson LD. Population based cancer registry analysis of primary tracheal carcinoma. Am J Clin Oncol. 2011, 34:32-7. 10.1097\/COC.0b013e3181cae8ab","journal-title":"Am J Clin Oncol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2010.06.004","article-title":"The compromised airway: tumors, strictures, and tracheomalacia","volume":"90","author":"Gaissert HA","year":"2010","unstructured":"Gaissert HA, Burns J. The compromised airway: tumors, strictures, and tracheomalacia. Surg Clin North Am. 2010, 90:1065-89. 10.1016\/j.suc.2010.06.004","journal-title":"Surg Clin North Am"},{"key":"ref8","article-title":"Primary small cell cancer of cervical trachea: a case report and literature review","volume":"8","author":"Qiu J","year":"2015","unstructured":"Qiu J, Lin W, Zhou ML, et al.. Primary small cell cancer of cervical trachea: a case report and literature review. Int J Clin Exp Pathol. 2015, 8:7488-93.","journal-title":"Int J Clin Exp Pathol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2004.05.064","article-title":"Long-term survival after resection of primary adenoid cystic and squamous cell carcinoma of the trachea and carina","volume":"78","author":"Gaissert HA","year":"2004","unstructured":"Gaissert HA, Grillo HC, Shadmehr MB, et al.. Long-term survival after resection of primary adenoid cystic and squamous cell carcinoma of the trachea and carina. Ann Thorac Surg. 2004, 78:1889-96; discussion 1896-7. 10.1016\/j.athoracsur.2004.05.064","journal-title":"Ann Thorac Surg"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1709937","article-title":"Durvalumab after chemoradiotherapy in stage III non-small-cell lung cancer","volume":"377","author":"Antonia SJ","year":"2017","unstructured":"Antonia SJ, Villegas A, Daniel D, et al.. Durvalumab after chemoradiotherapy in stage III non-small-cell lung cancer. N Engl J Med. 2017, 377:1919-29. 10.1056\/NEJMoa1709937","journal-title":"N Engl J Med"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.adro.2016.03.003","article-title":"Case report of tracheobronchial squamous cell carcinoma treated with radiation therapy and concurrent chemotherapy","volume":"1","author":"Agrawal V","year":"2016","unstructured":"Agrawal V, Marcoux JP, Rabin MS, et al.. Case report of tracheobronchial squamous cell carcinoma treated with radiation therapy and concurrent chemotherapy. Adv Radiat Oncol. 2016, 1:127-31. 10.1016\/j.adro.2016.03.003","journal-title":"Adv Radiat Oncol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(90)90358-d","article-title":"Primary tracheal tumors: treatment and results","volume":"49","author":"Grillo HC","year":"1990","unstructured":"Grillo HC, Mathisen DJ. Primary tracheal tumors: treatment and results. Ann Thorac Surg. 1990, 49:69-77. 10.1016\/0003-4975(90)90358-d","journal-title":"Ann Thorac Surg"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2018.08.067","article-title":"Complete tumor response of tracheal squamous cell carcinoma after treatment with pembrolizumab","volume":"107","author":"Maller B","year":"2019","unstructured":"Maller B, Kaszuba F, Tanvetyanon T. Complete tumor response of tracheal squamous cell carcinoma after treatment with pembrolizumab. Ann Thorac Surg. 2019, 107:e273-4. 10.1016\/j.athoracsur.2018.08.067","journal-title":"Ann Thorac Surg"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2016.08.021","article-title":"Successful treatment of an aggressive tracheal malignancy with immunotherapy","volume":"103","author":"Osho AA","year":"2017","unstructured":"Osho AA, Azzoli CJ, Pai S, et al.. Successful treatment of an aggressive tracheal malignancy with immunotherapy. Ann Thorac Surg. 2017, 103:e123-5. 10.1016\/j.athoracsur.2016.08.021","journal-title":"Ann Thorac Surg"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2022.02.003","article-title":"Characterizing immune-mediated adverse events with durvalumab in patients with unresectable stage III NSCLC: A post-hoc analysis of the PACIFIC trial","volume":"166","author":"Naidoo J","year":"2022","unstructured":"Naidoo J, Vansteenkiste JF, Faivre-Finn C, et al.. Characterizing immune-mediated adverse events with durvalumab in patients with unresectable stage III NSCLC: A post-hoc analysis of the PACIFIC trial. Lung Cancer. 2022, 166:84-93. 10.1016\/j.lungcan.2022.02.003","journal-title":"Lung Cancer"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/393456-definitive-chemoradiation-followed-by-consolidation-immunotherapy-for-unresectable-tracheal-squamous-cell-carcinoma-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,10]],"date-time":"2025-08-10T16:40:21Z","timestamp":1754844021000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/393456-definitive-chemoradiation-followed-by-consolidation-immunotherapy-for-unresectable-tracheal-squamous-cell-carcinoma-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,10]]},"references-count":15,"URL":"https:\/\/doi.org\/10.7759\/cureus.89737","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8,10]]}}}