{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T02:44:27Z","timestamp":1755225867040,"version":"3.43.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,13]]},"DOI":"10.7759\/cureus.90008","type":"journal-article","created":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T18:31:45Z","timestamp":1755109905000},"source":"Crossref","is-referenced-by-count":0,"title":["Tumoral Calcinosis of the Knee With Secondary Infection in a Patient With Juvenile Dermatomyositis: Management Approach and Pathophysiological and Therapeutic Review"],"prefix":"10.7759","author":[{"given":"Brandon Eric","family":"Dkhar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narendra","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M C","family":"Shashidhar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siddhartha  S","family":"Basumatary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vipul","family":"Pathak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-014-0467-y","article-title":"The presentation, assessment, pathogenesis, and treatment of calcinosis in juvenile dermatomyositis","volume":"16","author":"Hoeltzel MF","year":"2014","unstructured":"Hoeltzel MF, Oberle EJ, Robinson AB, Agarwal A, Rider LG. The presentation, assessment, pathogenesis, and treatment of calcinosis in juvenile dermatomyositis. Curr Rheumatol Rep. 2014, 16:467. 10.1007\/s11926-014-0467-y","journal-title":"Curr Rheumatol Rep"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2022.101768","article-title":"Calcinosis in dermatomyositis: origins and possible therapeutic avenues","volume":"36","author":"Davuluri S","year":"2022","unstructured":"Davuluri S, Duvvuri B, Lood C, Faghihi-Kashani S, Chung L. Calcinosis in dermatomyositis: origins and possible therapeutic avenues. Best Pract Res Clin Rheumatol. 2022, 36:101768. 10.1016\/j.berh.2022.101768","journal-title":"Best Pract Res Clin Rheumatol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33337","article-title":"Clinical variability of familial tumoral calcinosis caused by novel GALNT3 mutations","volume":"152A","author":"Ichikawa S","year":"2010","unstructured":"Ichikawa S, Baujat G, Seyahi A, et al.. Clinical variability of familial tumoral calcinosis caused by novel GALNT3 mutations. Am J Med Genet A. 2010, 152A:896-903. 10.1002\/ajmg.a.33337","journal-title":"Am J Med Genet A"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197502132920706","article-title":"Polymyositis and dermatomyositis - (first of two parts)","volume":"292","author":"Bohan A","year":"1975","unstructured":"Bohan A, Peter JB. Polymyositis and dermatomyositis - (first of two parts). N Engl J Med. 1975, 292:344-7. 10.1056\/NEJM197502132920706","journal-title":"N Engl J Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keu259","article-title":"Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset","volume":"53","author":"Tansley SL","year":"2014","unstructured":"Tansley SL, Betteridge ZE, Shaddick G, Gunawardena H, Arnold K, Wedderburn LR, McHugh NJ. Calcinosis in juvenile dermatomyositis is influenced by both anti-NXP2 autoantibody status and age at disease onset. Rheumatology (Oxford). 2014, 53:2204-8. 10.1093\/rheumatology\/keu259","journal-title":"Rheumatology (Oxford)"},{"key":"ref6","article-title":"Bone biomineralization in osteosarcoma: a multimodal multiscale in\/ex vivo study through synchrotron-based X-ray and NMR techniques","author":"Rossi F","unstructured":"Rossi F. Bone biomineralization in osteosarcoma: a multimodal multiscale in\/ex vivo study through synchrotron-based X-ray and NMR techniques. Alma Mater Studiorum Universit\u00e0 di Bologna, Bologna, Italy;"},{"key":"ref7","doi-asserted-by":"crossref","DOI":"10.1016\/S1050-1738(98)00014-0","article-title":"Noncollagenous matrix proteins controlling mineralization: possible role in pathologic calcification of vascular tissue","volume":"8","author":"Donley GE","year":"1998","unstructured":"Donley GE, Fitzpatrick LA. Noncollagenous matrix proteins controlling mineralization: possible role in pathologic calcification of vascular tissue. Trends in cardiovascular medicine. 1998, 8:199-206.","journal-title":"Trends in cardiovascular medicine"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.20900\/immunometab20210008","article-title":"Mitochondrial calcification","volume":"3","author":"Duvvuri B","year":"2021","unstructured":"Duvvuri B, Lood C. Mitochondrial calcification. Immunometabolism. 2021, 3:e210008. 10.20900\/immunometab20210008","journal-title":"Immunometabolism"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.01559","article-title":"Neutrophil extracellular traps formation and aggregation orchestrate induction and resolution of sterile crystal-mediated inflammation","volume":"9","author":"Li Y","year":"2018","unstructured":"Li Y, Cao X, Liu Y, Zhao Y, Herrmann M. Neutrophil extracellular traps formation and aggregation orchestrate induction and resolution of sterile crystal-mediated inflammation. Front Immunol. 2018, 9:1559. 10.3389\/fimmu.2018.01559","journal-title":"Front Immunol"},{"key":"ref10","article-title":"Fine needle aspiration cytology in tumoral calcinosis cases & review of literature","volume":"7","author":"Agarwal A","year":"2009","unstructured":"Agarwal A, Rijal A, Karki S, Upadhyay P. Fine needle aspiration cytology in tumoral calcinosis cases & review of literature. Sudanese Journal of Dermatology. 2009, 7:","journal-title":"Sudanese Journal of Dermatology"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12113687","article-title":"Ectopic calcification: what do we know and what is the way forward?","volume":"12","author":"Snijders BM","year":"2023","unstructured":"Snijders BM, Peters MJ, Koek HL. Ectopic calcification: what do we know and what is the way forward?. J Clin Med. 2023, 12:3687. 10.3390\/jcm12113687","journal-title":"J Clin Med"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.174.1.2294551","article-title":"Imaging of tumoral calcinosis: new observations","volume":"174","author":"Martinez S","year":"1990","unstructured":"Martinez S, Vogler JB 3rd, Harrelson JM, Lyles KW. Imaging of tumoral calcinosis: new observations. Radiology. 1990, 174:215-22. 10.1148\/radiology.174.1.2294551","journal-title":"Radiology"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1210\/en.2011-1137","article-title":"Dietary phosphate restriction normalizes biochemical and skeletal abnormalities in a murine model of tumoral calcinosis","volume":"152","author":"Ichikawa S","year":"2011","unstructured":"Ichikawa S, Austin AM, Gray AK, Allen MR, Econs MJ. Dietary phosphate restriction normalizes biochemical and skeletal abnormalities in a murine model of tumoral calcinosis. Endocrinology. 2011, 152:4504-13. 10.1210\/en.2011-1137","journal-title":"Endocrinology"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04153.x","article-title":"An extremely severe case of cutaneous calcinosis with juvenile dermatomyositis, and successful treatment with diltiazem","volume":"144","author":"Ichiki Y","year":"2001","unstructured":"Ichiki Y, Akiyama T, Shimozawa N, Suzuki Y, Kondo N, Kitajima Y. An extremely severe case of cutaneous calcinosis with juvenile dermatomyositis, and successful treatment with diltiazem. Br J Dermatol. 2001, 144:894-7. 10.1046\/j.1365-2133.2001.04153.x","journal-title":"Br J Dermatol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2016-1087","article-title":"Topical sodium thiosulfate: a treatment for calcifications in hyperphosphatemic familial tumoral calcinosis?","volume":"101","author":"Jost J","year":"2016","unstructured":"Jost J, Bahans C, Courbebaisse M, et al.. Topical sodium thiosulfate: a treatment for calcifications in hyperphosphatemic familial tumoral calcinosis?. J Clin Endocrinol Metab. 2016, 101:2810-5. 10.1210\/jc.2016-1087","journal-title":"J Clin Endocrinol Metab"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines9111698","article-title":"Bisphosphonates for the treatment of calcinosis cutis-a retrospective single-center study","volume":"9","author":"Rauch L","year":"2021","unstructured":"Rauch L, Hein R, Biedermann T, Eyerich K, Lauffer F. Bisphosphonates for the treatment of calcinosis cutis-a retrospective single-center study. Biomedicines. 2021, 9:1698. 10.3390\/biomedicines9111698","journal-title":"Biomedicines"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/1476-4598-13-265","article-title":"Probenecid as a sensitizer of bisphosphonate-mediated effects in breast cancer cells","volume":"13","author":"Ebert R","year":"2014","unstructured":"Ebert R, Meissner-Weigl J, Zeck S, et al.. Probenecid as a sensitizer of bisphosphonate-mediated effects in breast cancer cells. Mol Cancer. 2014, 13:265. 10.1186\/1476-4598-13-265","journal-title":"Mol Cancer"},{"key":"ref18","doi-asserted-by":"crossref","DOI":"10.1007\/s40674-016-0035-x","article-title":"Management of calcinosis associated with systemic sclerosis","volume":"2","author":"Valenzuela A","year":"2016","unstructured":"Valenzuela A, Chung L. Management of calcinosis associated with systemic sclerosis. Curr Treat Options in Rheum. 2016, 2:85-96.","journal-title":"Curr Treat Options in Rheum"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.12.035","article-title":"Treatment of calcinosis cutis by extracorporeal shock-wave lithotripsy","volume":"66","author":"Sultan-Bichat N","year":"2012","unstructured":"Sultan-Bichat N, Menard J, Perceau G, Staerman F, Bernard P, Reguia\u00ef Z. Treatment of calcinosis cutis by extracorporeal shock-wave lithotripsy. J Am Acad Dermatol. 2012, 66:424-9. 10.1016\/j.jaad.2010.12.035","journal-title":"J Am Acad Dermatol"},{"key":"ref20","article-title":"FRI0403 Mitochondrial dysfunction and oxidative stress in myositis: a central pathogenic pathway from mouse to man","volume":"1","author":"Boyer O","year":"2018","unstructured":"Boyer O, Meyer A, Boitard C, Abad C. FRI0403 Mitochondrial dysfunction and oxidative stress in myositis: a central pathogenic pathway from mouse to man. Annals of the Rheumatic Diseases. 2018, 1:734.","journal-title":"Annals of the Rheumatic Diseases"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/385667-tumoral-calcinosis-of-the-knee-with-secondary-infection-in-a-patient-with-juvenile-dermatomyositis-management-approach-and-pathophysiological-and-therapeutic-review","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T18:31:46Z","timestamp":1755109906000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/385667-tumoral-calcinosis-of-the-knee-with-secondary-infection-in-a-patient-with-juvenile-dermatomyositis-management-approach-and-pathophysiological-and-therapeutic-review"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,13]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.90008","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8,13]]}}}