{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T14:40:10Z","timestamp":1755960010008,"version":"3.44.0"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,23]]},"DOI":"10.7759\/cureus.90816","type":"journal-article","created":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T14:24:52Z","timestamp":1755959092000},"source":"Crossref","is-referenced-by-count":0,"title":["Esophageal Variceal Grading and Platelet Count in Patients With Liver Cirrhosis"],"prefix":"10.7759","author":[{"given":"Muhammad","family":"Farooq","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Usman","family":"Sadiq","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qaiser","family":"Wadud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abbas","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dania","family":"Khawar Rahman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Imran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahnoor","family":"Safeer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syeda Hafsa","family":"Habib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tayaba Syed","family":"Habib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/895787","article-title":"Pathophysiology of portal hypertension and esophageal varices","volume":"2012","author":"Maruyama H","year":"2012","unstructured":"Maruyama H, Yokosuka O. Pathophysiology of portal hypertension and esophageal varices. Int J Hepatol. 2012, 2012:895787. 10.1155\/2012\/895787","journal-title":"Int J Hepatol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3390\/medsci13010013","article-title":"Update on the complications and management of liver cirrhosis","volume":"13","author":"Fadlallah H","year":"2025","unstructured":"Fadlallah H, El Masri D, Bahmad HF, Abou-Kheir W, El Masri J. Update on the complications and management of liver cirrhosis. Med Sci (Basel). 2025, 13:13. 10.3390\/medsci13010013","journal-title":"Med Sci (Basel)"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1186\/s12880-025-01681-6","article-title":"Predictive value of high-risk esophageal varices in cirrhosis based on dual-energy CT combined with clinical and serologic features","volume":"25","author":"Chen J","year":"2025","unstructured":"Chen J, Zhang F, Wu S, et al.. Predictive value of high-risk esophageal varices in cirrhosis based on dual-energy CT combined with clinical and serologic features. BMC Med Imaging. 2025, 25:137. 10.1186\/s12880-025-01681-6","journal-title":"BMC Med Imaging"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4103\/1319-3767.74470","article-title":"Non-invasive predictors of esophageal varices","volume":"17","author":"Cherian JV","year":"2011","unstructured":"Cherian JV, Deepak N, Ponnusamy RP, Somasundaram A, Jayanthi V. Non-invasive predictors of esophageal varices. Saudi J Gastroenterol. 2011, 17:64-8. 10.4103\/1319-3767.74470","journal-title":"Saudi J Gastroenterol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.56433","article-title":"Non-invasive fibrosis markers for predicting esophageal varices: a potential alternative to endoscopic screening","volume":"16","author":"Ali K","year":"2024","unstructured":"Ali K, Slah-Ud-Din S, Afzal M, Tariq MR, Waheed T, Yousuf H. Non-invasive fibrosis markers for predicting esophageal varices: a potential alternative to endoscopic screening. Cureus. 2024, 16:e56433. 10.7759\/cureus.56433","journal-title":"Cureus"},{"key":"ref6","article-title":"A study of non-invasive predictors of esophageal varices in patients with cirrhosis of liver - a cross-sectional study","volume":"3","author":"Mujahid N","year":"2024","unstructured":"Mujahid N, Aithal K, Dhananjaya M. A study of non-invasive predictors of esophageal varices in patients with cirrhosis of liver - a cross-sectional study. Asian J Med Sci. 2024, 3:73-8.","journal-title":"Asian J Med Sci"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.mjafi.2021.08.008","article-title":"Transient elastography and platelet count as noninvasive predictors of gastroesophageal varices in patients with compensated hepatitis C virus-related liver cirrhosis","volume":"79","author":"Elbasiony M","year":"2023","unstructured":"Elbasiony M, Abed H, Alaskalany HM, Saleh A. Transient elastography and platelet count as noninvasive predictors of gastroesophageal varices in patients with compensated hepatitis C virus-related liver cirrhosis. Med J Armed Forces India. 2023, 79:710-7. 10.1016\/j.mjafi.2021.08.008","journal-title":"Med J Armed Forces India"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.20524\/aog.2019.0429","article-title":"Validating and expanding the Baveno VI criteria for esophageal varices in patients with advanced liver disease: a multicenter study","volume":"33","author":"Protopapas AA","year":"2020","unstructured":"Protopapas AA, Mylopoulou T, Papadopoulos VP, Vogiatzi K, Goulis I, Mimidis K. Validating and expanding the Baveno VI criteria for esophageal varices in patients with advanced liver disease: a multicenter study. Ann Gastroenterol. 2020, 33:87-94. 10.20524\/aog.2019.0429","journal-title":"Ann Gastroenterol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10018-1129","article-title":"Epidemiology of viral hepatitis and liver diseases in Pakistan","volume":"5","author":"Butt AS","year":"2015","unstructured":"Butt AS. Epidemiology of viral hepatitis and liver diseases in Pakistan. Euroasian J Hepatogastroenterol. 2015, 5:43-8. 10.5005\/jp-journals-10018-1129","journal-title":"Euroasian J Hepatogastroenterol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.81507","article-title":"Comparison of different non-invasive indices in predicting high-risk esophageal varices in a Pakistani population","volume":"17","author":"Balouch AW","year":"2025","unstructured":"Balouch AW, Tareen K, Hyder A, et al.. Comparison of different non-invasive indices in predicting high-risk esophageal varices in a Pakistani population. Cureus. 2025, 17:e81507. 10.7759\/cureus.81507","journal-title":"Cureus"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.281053","article-title":"World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects","volume":"310","year":"2013","unstructured":"World Medical Association Declaration of Helsinki. ethical principles for medical research involving human subjects. JAMA. 2013, 310:2191-4. 10.1001\/jama.2013.281053","journal-title":"JAMA"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39335.541782.AD","article-title":"Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies","volume":"335","author":"von Elm E","year":"2007","unstructured":"von Elm E, Altman DG, Egger M, Pocock SJ, G\u00f8tzsche PC, Vandenbroucke JP. Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. BMJ. 2007, 335:806-8. 10.1136\/bmj.39335.541782.AD","journal-title":"BMJ"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136\/gut.52.8.1200","article-title":"Platelet count\/spleen diameter ratio: proposal and validation of a non-invasive parameter to predict the presence of oesophageal varices in patients with liver cirrhosis","volume":"52","author":"Giannini E","year":"2003","unstructured":"Giannini E, Botta F, Borro P, et al.. Platelet count\/spleen diameter ratio: proposal and validation of a non-invasive parameter to predict the presence of oesophageal varices in patients with liver cirrhosis. Gut. 2003, 52:1200-5. 10.1136\/gut.52.8.1200","journal-title":"Gut"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1443-1661.2009.00929.x","article-title":"General rules for recording endoscopic findings of esophagogastric varices (2nd edition)","volume":"22","author":"Tajiri T","year":"2010","unstructured":"Tajiri T, Yoshida H, Obara K, et al.. General rules for recording endoscopic findings of esophagogastric varices (2nd edition). Dig Endosc. 2010, 22:1-9. 10.1111\/j.1443-1661.2009.00929.x","journal-title":"Dig Endosc"},{"key":"ref15","article-title":"Platelet count\/spleen diameter ratio to predict the presence of esophageal varices in patients with cirrhosis: a systematic review","volume":"24","author":"Chawla S","year":"2012","unstructured":"Chawla S, Katz A, Attar BM, Gupta A, Sandhu DS, Agarwal R. Platelet count\/spleen diameter ratio to predict the presence of esophageal varices in patients with cirrhosis: a systematic review. Eur J Gastroenterol Hepatol. 2012, 24:431-6.","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i8.2079","article-title":"Platelet count\/spleen diameter ratio to predict esophageal varices in Mexican patients with hepatic cirrhosis","volume":"20","author":"Gonz\u00e1lez-Ojeda A","year":"2014","unstructured":"Gonz\u00e1lez-Ojeda A, Cervantes-Guevara G, Ch\u00e1vez-S\u00e1nchez M, et al.. Platelet count\/spleen diameter ratio to predict esophageal varices in Mexican patients with hepatic cirrhosis. World J Gastroenterol. 2014, 20:2079-84. 10.3748\/wjg.v20.i8.2079","journal-title":"World J Gastroenterol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.28005.2","article-title":"Platelet count can predict the grade of esophageal varices in cirrhotic patients: a cross-sectional study","volume":"10","author":"Afsar A","year":"2021","unstructured":"Afsar A, Nadeem M, Shah SA, Hussain H, Rani A, Ghaffar S. Platelet count can predict the grade of esophageal varices in cirrhotic patients: a cross-sectional study. F1000Res. 2021, 10:101. 10.12688\/f1000research.28005.2","journal-title":"F1000Res"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3889\/oamjms.2022.9058","article-title":"Correlation between platelet count and grading of esophageal varices in liver cirrhosis patients: a meta-analysis","volume":"10","author":"Baihaqi FA","year":"2022","unstructured":"Baihaqi FA, Delarosa DO. Correlation between platelet count and grading of esophageal varices in liver cirrhosis patients: a meta-analysis. Open Access Maced J Med Sci [Internet]. 2022, 10:513-21. 10.3889\/oamjms.2022.9058","journal-title":"Open Access Maced J Med Sci [Internet]"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/4217512","article-title":"Validation and refinement of the Baveno VI criteria for ruling out high-risk varices","volume":"2020","author":"Zhou H","year":"2020","unstructured":"Zhou H, Hu H, Tian M, Chu J, Tian C, Yang Y, Lin S. Validation and refinement of the Baveno VI criteria for ruling out high-risk varices. Gastroenterol Res Pract. 2020, 2020:4217512. 10.1155\/2020\/4217512","journal-title":"Gastroenterol Res Pract"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1999.01540.x","article-title":"Factors predicting the presence of esophageal or gastric varices in patients with advanced liver disease","volume":"94","author":"Zaman A","year":"1999","unstructured":"Zaman A, Hapke R, Flora K, Rosen HR, Benner K. Factors predicting the presence of esophageal or gastric varices in patients with advanced liver disease. Am J Gastroenterol. 1999, 94:3292-6. 10.1111\/j.1572-0241.1999.01540.x","journal-title":"Am J Gastroenterol"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1999.1539_a.x","article-title":"Predictors of large esophageal varices in patients with cirrhosis","volume":"94","author":"Chalasani N","year":"1999","unstructured":"Chalasani N, Imperiale TF, Ismail A, et al.. Predictors of large esophageal varices in patients with cirrhosis. Am J Gastroenterol. 1999, 94:3285-91. 10.1111\/j.1572-0241.1999.1539_a.x","journal-title":"Am J Gastroenterol"},{"key":"ref22","article-title":"Use of the Child Pugh score in liver disease","author":"Tsoris A","year":"2023","unstructured":"Tsoris A, Marlar CA. Use of the Child Pugh score in liver disease. StatPearls [Internet]. StatPearls Publishing, Treasure Island (FL); 2023."},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1097\/HC9.0000000000000682","article-title":"Screening and management of portal hypertension and varices in cirrhosis: expert perspectives","volume":"9","author":"Brown RS Jr","year":"2025","unstructured":"Brown RS Jr, Brown KA, Flamm S, Bejarano RE, Rahimi RS, Singal AK, Rockey DC. Screening and management of portal hypertension and varices in cirrhosis: expert perspectives. Hepatol Commun. 2025, 9:e0682. 10.1097\/HC9.0000000000000682","journal-title":"Hepatol Commun"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.4103\/jfmpc.jfmpc_792_23","article-title":"Non-invasive predictors to grade esophageal varices in liver cirrhosis patients","volume":"13","author":"Rapelly SS","year":"2024","unstructured":"Rapelly SS, Singh S, Verma N, Bhattacharya S, Rungta S. Non-invasive predictors to grade esophageal varices in liver cirrhosis patients. J Family Med Prim Care. 2024, 13:1232-7. 10.4103\/jfmpc.jfmpc_792_23","journal-title":"J Family Med Prim Care"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.49078","article-title":"Liver disease-related sarcopenia: a predictor of poor prognosis by accelerating hepatic decompensation in advanced chronic liver disease","volume":"15","author":"Nakamura A","year":"2023","unstructured":"Nakamura A, Yoshimura T, Ichikawa T. Liver disease-related sarcopenia: a predictor of poor prognosis by accelerating hepatic decompensation in advanced chronic liver disease. Cureus. 2023, 15:e49078. 10.7759\/cureus.49078","journal-title":"Cureus"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/399174-esophageal-variceal-grading-and-platelet-count-in-patients-with-liver-cirrhosis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,23]],"date-time":"2025-08-23T14:24:53Z","timestamp":1755959093000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/399174-esophageal-variceal-grading-and-platelet-count-in-patients-with-liver-cirrhosis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,23]]},"references-count":25,"URL":"https:\/\/doi.org\/10.7759\/cureus.90816","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8,23]]}}}