{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T21:16:13Z","timestamp":1790630173273,"version":"4.1.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,21]]},"DOI":"10.7759\/cureus.9314","type":"journal-article","created":{"date-parts":[[2020,7,21]],"date-time":"2020-07-21T12:25:27Z","timestamp":1595334327000},"source":"Crossref","is-referenced-by-count":2,"title":["A Saudi Child With Chronic Immune Thrombocytopenia and Vitiligo"],"prefix":"10.7759","author":[{"given":"Abdulqader","family":"Alhebshi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasanat","family":"Abbas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidayah  M","family":"Alotaibi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Attaf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arwa","family":"Al-Yamani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-07-162503","article-title":"Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group","volume":"12","author":"Rodeghiero F","year":"2009","unstructured":"Rodeghiero F, Stasi R, Gernsheimer T, et al.. Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group. Blood. 2009, 12:2386-93. 10.1182\/blood-2008-07-162503","journal-title":"Blood"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.21616","article-title":"The incidence of immune thrombocytopenic purpura in children and adults: a critical review of published reports","volume":"85","author":"Terrell DR","year":"2010","unstructured":"Terrell DR, Beebe LA, Vesely SK, Neas BR, Segal JB, George JN. The incidence of immune thrombocytopenic purpura in children and adults: a critical review of published reports. Am J Hematol. 2010, 85:174-80. 10.1002\/ajh.21616","journal-title":"Am J Hematol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3390\/jcm6020016","article-title":"Pathogenesis and therapeutic mechanisms in immune thrombocytopenia (ITP)","volume":"6","author":"Zufferey A","year":"2017","unstructured":"Zufferey A, Kapur R, Semple JW. Pathogenesis and therapeutic mechanisms in immune thrombocytopenia (ITP). J Clin Med. 2017, 6:16. 10.3390\/jcm6020016","journal-title":"J Clin Med"},{"key":"ref4","article-title":"Childhood immune thrombocytopenia: clinical presentation and management","volume":"12","author":"Me FO","year":"2012","unstructured":"Me FO. Childhood immune thrombocytopenia: clinical presentation and management. Sudan J Paediatr. 2012, 12:27-39. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4949815\/","journal-title":"Sudan J Paediatr"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.20982","article-title":"Splenectomy and spontaneous remission in children with chronic idiopathic thrombocytopenic purpura","volume":"15","author":"Donato H","year":"2006","unstructured":"Donato H, Pic\u00f3n A, Rapetti MC, et al.. Splenectomy and spontaneous remission in children with chronic idiopathic thrombocytopenic purpura. Pediatr Blood Cancer. 2006, 15:737-9. 10.1002\/pbc.20982","journal-title":"Pediatr Blood Cancer"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-04-215525","article-title":"Intracranial hemorrhage (ICH) in children with immune thrombocytopenia (ITP): study of 40 cases","volume":"26","author":"Psaila B","year":"2009","unstructured":"Psaila B, Petrovic A, Page LK, Menell J, Schonholz M, Bussel JB. Intracranial hemorrhage (ICH) in children with immune thrombocytopenia (ITP): study of 40 cases. Blood. 2009, 26:4777-83. 10.1182\/blood-2009-04-215525","journal-title":"Blood"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-010-0090-5","article-title":"The long-term impact of rituximab for childhood immune thrombocytopenia","volume":"12","author":"Cooper N","year":"2010","unstructured":"Cooper N, Bussel JB. The long-term impact of rituximab for childhood immune thrombocytopenia. Curr Rheumatol Rep. 2010, 12:94-100. 10.1007\/s11926-010-0090-5","journal-title":"Curr Rheumatol Rep"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-11-393975","article-title":"Outcomes 5 years after response to rituximab therapy in children and adults with immune thrombocytopenia","volume":"21","author":"Patel VL","year":"2012","unstructured":"Patel VL, Mah\u00e9vas M, Lee SY, et al.. Outcomes 5 years after response to rituximab therapy in children and adults with immune thrombocytopenia. Blood. 2012, 21:5989-95. 10.1182\/blood-2011-11-393975","journal-title":"Blood"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0036698","article-title":"Rituximab for children with immune thrombocytopenia: a systematic review","volume":"7","author":"Liang Y","year":"2012","unstructured":"Liang Y, Zhang L, Gao J, Hu D, Ai Y. Rituximab for children with immune thrombocytopenia: a systematic review. PloS One. 2012, 7:36698. 10.1371\/journal.pone.0036698","journal-title":"PloS One"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2012.1.444","article-title":"Childhood immune thrombocytopenia: role of rituximab, recombinant thrombopoietin, and other new therapeutics","volume":"2012","author":"Journeycake JM","year":"2012","unstructured":"Journeycake JM. Childhood immune thrombocytopenia: role of rituximab, recombinant thrombopoietin, and other new therapeutics. Hematol Am Soc Hematol Educ Program. 2012, 2012:444-9. 10.1182\/asheducation-2012.1.444","journal-title":"Hematol Am Soc Hematol Educ Program"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.10.452","article-title":"Demographic and clinical properties of juvenile-onset Beh\u00e7et\u2019s disease: a controlled multicenter study","volume":"58","author":"Karincaoglu Y","year":"2008","unstructured":"Karincaoglu Y, Borlu M, Toker SC, et al.. Demographic and clinical properties of juvenile-onset Beh\u00e7et\u2019s disease: a controlled multicenter study. J Am Acad Dermatol. 2008, 58:579-84. 10.1016\/j.jaad.2007.10.452","journal-title":"J Am Acad Dermatol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.00399","article-title":"NF-\u03baB pathway in autoinflammatory diseases: dysregulation of protein modifications by ubiquitin defines a new category of autoinflammatory diseases","volume":"8","author":"Aksentijevich I","year":"2017","unstructured":"Aksentijevich I, Zhou Q. NF-\u03baB pathway in autoinflammatory diseases: dysregulation of protein modifications by ubiquitin defines a new category of autoinflammatory diseases. Front Immunol. 2017, 8:399. 10.3389\/fimmu.2017.00399","journal-title":"Front Immunol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3459","article-title":"Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease","volume":"48","author":"Zhou Q","year":"2016","unstructured":"Zhou Q, Wang H, Schwartz DM, et al.. Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease. Nat Genet. 2016, 48:67-73. 10.1038\/ng.3459","journal-title":"Nat Genet"},{"key":"ref14","article-title":"A case of idiopathic thrombocytopenic purpura in a patient with Behcet\u2019s disease","volume":"30","author":"Shin HY","year":"2005","unstructured":"Shin HY, Nam HJ, Song JK, et al.. A case of idiopathic thrombocytopenic purpura in a patient with Behcet\u2019s disease. J Rheum Dis. 2005, 30:137-42.","journal-title":"J Rheum Dis"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/35377-a-saudi-child-with-chronic-immune-thrombocytopenia-and-vitiligo","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:27:50Z","timestamp":1707506870000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/35377-a-saudi-child-with-chronic-immune-thrombocytopenia-and-vitiligo"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,21]]},"references-count":14,"URL":"https:\/\/doi.org\/10.7759\/cureus.9314","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7,21]]}}}