{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T02:40:04Z","timestamp":1759718404690,"version":"build-2065373602"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,5]]},"DOI":"10.7759\/cureus.93894","type":"journal-article","created":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T02:26:42Z","timestamp":1759717602000},"source":"Crossref","is-referenced-by-count":0,"title":["Predictive Accuracy of First-Trimester Biochemical and Clinical Markers in the Early Identification of Gestational Diabetes Mellitus: A Prospective Observational Study"],"prefix":"10.7759","author":[{"given":"Prithika","family":"B","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Revathy","family":"T.G","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jahnavi","family":"Chandrasekar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.2337\/dc10-S062","article-title":"Diagnosis and classification of diabetes mellitus","volume":"33","year":"2010","unstructured":"Diagnosis and classification of diabetes mellitus. Diabetes Care. 2010, 33.S62-9. 10.2337\/dc10-S062","journal-title":"Diabetes Care"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-1848","article-title":"International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy","volume":"33","author":"Metzger BE","year":"2010","unstructured":"Metzger BE, Gabbe SG, Persson B, et al.. International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy. Diabetes Care. 2010, 33:676-82. 10.2337\/dc09-1848","journal-title":"Diabetes Care"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-1641","article-title":"Frequency of gestational diabetes mellitus at collaborating centers based on IADPSG consensus panel-recommended criteria: the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study","volume":"35","author":"Sacks DA","year":"2012","unstructured":"Sacks DA, Hadden DR, Maresh M, et al.. Frequency of gestational diabetes mellitus at collaborating centers based on IADPSG consensus panel-recommended criteria: the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study. Diabetes Care. 2012, 35:526-8. 10.2337\/dc11-1641","journal-title":"Diabetes Care"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4103\/2230-8210.183469","article-title":"Comparison of maternal and fetal outcomes among Asian Indian pregnant women with or without gestational diabetes mellitus: a situational analysis study (WINGS-3)","volume":"20","author":"Mahalakshmi MM","year":"2016","unstructured":"Mahalakshmi MM, Bhavadharini B, Maheswari K, et al.. Comparison of maternal and fetal outcomes among Asian Indian pregnant women with or without gestational diabetes mellitus: a situational analysis study (WINGS-3). Indian J Endocrinol Metab. 2016, 20:491-6. 10.4103\/2230-8210.183469","journal-title":"Indian J Endocrinol Metab"},{"key":"ref5","unstructured":"International Diabetes Federation Atlas D. (2019). Accessed. 23.05.2025: https:\/\/diabetesatlas.org\/resources\/previous-editions\/."},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.49.8.634","article-title":"Serum lipid, lipoprotein and apolipoprotein changes in gestational diabetes mellitus: a cross-sectional and prospective study","volume":"49","author":"Koukkou E","year":"1996","unstructured":"Koukkou E, Watts GF, Lowy C. Serum lipid, lipoprotein and apolipoprotein changes in gestational diabetes mellitus: a cross-sectional and prospective study. J Clin Pathol. 1996, 49:634-7. 10.1136\/jcp.49.8.634","journal-title":"J Clin Pathol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/BF03345527","article-title":"Inflammatory markers in women with a recent history of gestational diabetes mellitus","volume":"28","author":"Di Benedetto A","year":"2005","unstructured":"Di Benedetto A, Russo GT, Corrado F, et al.. Inflammatory markers in women with a recent history of gestational diabetes mellitus. J Endocrinol Invest. 2005, 28:34-8. 10.1007\/BF03345527","journal-title":"J Endocrinol Invest"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.2004.00578.x","article-title":"A prospective study of maternal serum C-reactive protein (CRP) concentrations and risk of gestational diabetes mellitus","volume":"18","author":"Qiu C","year":"2004","unstructured":"Qiu C, Sorensen TK, Luthy DA, Williams MA. A prospective study of maternal serum C-reactive protein (CRP) concentrations and risk of gestational diabetes mellitus. Paediatr Perinat Epidemiol. 2004, 18:377-84. 10.1111\/j.1365-3016.2004.00578.x","journal-title":"Paediatr Perinat Epidemiol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.26.3.819","article-title":"First-trimester C-reactive protein and subsequent gestational diabetes","volume":"26","author":"Wolf M","year":"2003","unstructured":"Wolf M, Sandler L, Hsu K, Vossen-Smirnakis K, Ecker JL, Thadhani R. First-trimester C-reactive protein and subsequent gestational diabetes. Diabetes Care. 2003, 26:819-24. 10.2337\/diacare.26.3.819","journal-title":"Diabetes Care"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-030186","article-title":"C-reactive protein and gestational diabetes: the central role of maternal obesity","volume":"88","author":"Retnakaran R","year":"2003","unstructured":"Retnakaran R, Hanley AJ, Raif N, Connelly PW, Sermer M, Zinman B. C-reactive protein and gestational diabetes: the central role of maternal obesity. J Clin Endocrinol Metab. 2003, 88:3507-12. 10.1210\/jc.2003-030186","journal-title":"J Clin Endocrinol Metab"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-024-18024-9","article-title":"National and regional prevalence of gestational diabetes mellitus in India: a systematic review and meta-analysis","volume":"24","author":"Mantri N","year":"2024","unstructured":"Mantri N, Goel AD, Patel M, et al.. National and regional prevalence of gestational diabetes mellitus in India: a systematic review and meta-analysis. BMC Public Health. 2024, 24:527. 10.1186\/s12889-024-18024-9","journal-title":"BMC Public Health"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1177\/20503121221109911","article-title":"Association between body mass index in the first half of pregnancy and gestational diabetes: a systematic review","volume":"10","author":"Rahnemaei FA","year":"2022","unstructured":"Rahnemaei FA, Abdi F, Kazemian E, Shaterian N, Shaterian N, Behesht Aeen F. Association between body mass index in the first half of pregnancy and gestational diabetes: a systematic review. SAGE Open Med. 2022, 10:20503121221109911. 10.1177\/20503121221109911","journal-title":"SAGE Open Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.3.650","article-title":"Impact of iron deficiency anemia on prevalence of gestational diabetes mellitus","volume":"27","author":"Lao TT","year":"2004","unstructured":"Lao TT, Ho LF. Impact of iron deficiency anemia on prevalence of gestational diabetes mellitus. Diabetes Care. 2004, 27:650-6. 10.2337\/diacare.27.3.650","journal-title":"Diabetes Care"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.4239\/wjd.v6.i6.782","article-title":"Gestational diabetes mellitus: an update on the current international diagnostic criteria","volume":"6","author":"Agarwal MM","year":"2015","unstructured":"Agarwal MM. Gestational diabetes mellitus: an update on the current international diagnostic criteria. World J Diabetes. 2015, 6:782-91. 10.4239\/wjd.v6.i6.782","journal-title":"World J Diabetes"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2022.121069","article-title":"Polycystic ovary syndrome (PCOS) increases the risk of subsequent gestational diabetes mellitus (GDM): a novel therapeutic perspective","volume":"310","author":"Choudhury AA","year":"2022","unstructured":"Choudhury AA, Rajeswari VD. Polycystic ovary syndrome (PCOS) increases the risk of subsequent gestational diabetes mellitus (GDM): a novel therapeutic perspective. Life Sci. 2022, 310:121069. 10.1016\/j.lfs.2022.121069","journal-title":"Life Sci"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-023-05670-x","article-title":"Risk prediction of gestational diabetes mellitus in women with polycystic ovary syndrome based on a nomogram model","volume":"23","author":"Ouyang P","year":"2023","unstructured":"Ouyang P, Duan S, You Y, Jia X, Yang L. Risk prediction of gestational diabetes mellitus in women with polycystic ovary syndrome based on a nomogram model. BMC Pregnancy Childbirth. 2023, 23:408. 10.1186\/s12884-023-05670-x","journal-title":"BMC Pregnancy Childbirth"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2021.101293","article-title":"Serum uric acid in early pregnancy and risk of gestational diabetes mellitus: a cohort study of 85,609 pregnant women","volume":"48","author":"Zhao Y","year":"2022","unstructured":"Zhao Y, Zhao Y, Fan K, Jin L. Serum uric acid in early pregnancy and risk of gestational diabetes mellitus: a cohort study of 85,609 pregnant women. Diabetes Metab. 2022, 48:101293. 10.1016\/j.diabet.2021.101293","journal-title":"Diabetes Metab"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1038\/ajh.2010.262","article-title":"First trimester uric acid and adverse pregnancy outcomes","volume":"24","author":"Laughon SK","year":"2011","unstructured":"Laughon SK, Catov J, Powers RW, Roberts JM, Gandley RE. First trimester uric acid and adverse pregnancy outcomes. Am J Hypertens. 2011, 24:489-95. 10.1038\/ajh.2010.262","journal-title":"Am J Hypertens"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/jdi.14022","article-title":"Maternal uric acid levels and risk of gestational diabetes mellitus: a systematic review and dose-response meta-analysis of cohort studies including 105,380 participants","volume":"14","author":"Nikparast A","year":"2023","unstructured":"Nikparast A, Rahmani J, Bagheri R, Mohammadpour S, Shadnoosh M, Wong A, Ghanavati M. Maternal uric acid levels and risk of gestational diabetes mellitus: a systematic review and dose-response meta-analysis of cohort studies including 105,380 participants. J Diabetes Investig. 2023, 14:973-84. 10.1111\/jdi.14022","journal-title":"J Diabetes Investig"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.4103\/2249-4863.219995","article-title":"The prevalence of elevated high-sensitivity C-reactive protein in normal pregnancy and gestational diabetes mellitus","volume":"6","author":"Kumari R","year":"2017","unstructured":"Kumari R, Singh H. The prevalence of elevated high-sensitivity C-reactive protein in normal pregnancy and gestational diabetes mellitus. J Family Med Prim Care. 2017, 6:259-64. 10.4103\/2249-4863.219995","journal-title":"J Family Med Prim Care"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1172\/JCI24531","article-title":"Gestational diabetes mellitus","volume":"115","author":"Buchanan TA","year":"2005","unstructured":"Buchanan TA, Xiang AH. Gestational diabetes mellitus. J Clin Invest. 2005, 115:485-91. 10.1172\/JCI24531","journal-title":"J Clin Invest"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0085716","article-title":"Maternal biomarkers of endothelial dysfunction and preterm delivery","volume":"9","author":"Chen X","year":"2014","unstructured":"Chen X, Scholl TO. Maternal biomarkers of endothelial dysfunction and preterm delivery. PLoS One. 2014, 9:e85716. 10.1371\/journal.pone.0085716","journal-title":"PLoS One"},{"key":"ref23","article-title":"Low socioeconomic status as a risk factor for gestational diabetes","volume":"28","author":"Bo S","year":"2002","unstructured":"Bo S, Menato G, Bardelli C, et al.. Low socioeconomic status as a risk factor for gestational diabetes. Diabetes Metab. 2002, 28:139-40.","journal-title":"Diabetes Metab"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1038\/s41387-025-00372-z","article-title":"Novel first-trimester serum biomarkers for early prediction of gestational diabetes mellitus","volume":"15","author":"Tian S","year":"2025","unstructured":"Tian S, Liu M, Han S, et al.. Novel first-trimester serum biomarkers for early prediction of gestational diabetes mellitus. Nutr Diabetes. 2025, 15:15. 10.1038\/s41387-025-00372-z","journal-title":"Nutr Diabetes"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.112183","article-title":"Gestational\u00a0diabetes mellitus - a metabolic and reproductive disorder","volume":"143","author":"Choudhury AA","year":"2021","unstructured":"Choudhury AA, Devi Rajeswari V. Gestational\u00a0diabetes mellitus - a metabolic and reproductive disorder. Biomed Pharmacother. 2021, 143:112183. 10.1016\/j.biopha.2021.112183","journal-title":"Biomed Pharmacother"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0902430","article-title":"A multicenter, randomized trial of treatment for mild gestational diabetes","volume":"361","author":"Landon MB","year":"2009","unstructured":"Landon MB, Spong CY, Thom E, et al.. A multicenter, randomized trial of treatment for mild gestational diabetes. N Engl J Med. 2009, 361:1339-48. 10.1056\/NEJMoa0902430","journal-title":"N Engl J Med"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1097\/GRF.0b013e31815a5494","article-title":"Metabolic changes in pregnancy","volume":"50","author":"Lain KY","year":"2007","unstructured":"Lain KY, Catalano PM. Metabolic changes in pregnancy. Clin Obstet Gynecol. 2007, 50:938-48. 10.1097\/GRF.0b013e31815a5494","journal-title":"Clin Obstet Gynecol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/422333-predictive-accuracy-of-first-trimester-biochemical-and-clinical-markers-in-the-early-identification-of-gestational-diabetes-mellitus-a-prospective-observational-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T02:26:48Z","timestamp":1759717608000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/422333-predictive-accuracy-of-first-trimester-biochemical-and-clinical-markers-in-the-early-identification-of-gestational-diabetes-mellitus-a-prospective-observational-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,5]]},"references-count":27,"URL":"https:\/\/doi.org\/10.7759\/cureus.93894","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10,5]]}}}