{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T22:10:41Z","timestamp":1760998241413,"version":"build-2065373602"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,20]]},"DOI":"10.7759\/cureus.95007","type":"journal-article","created":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T21:50:34Z","timestamp":1760997034000},"source":"Crossref","is-referenced-by-count":0,"title":["A Case of Severe Hyponatremia Unmasking Borderline Heart Failure With Preserved Ejection Fraction With Right Ventricular Dysfunction"],"prefix":"10.7759","author":[{"given":"Urshila","family":"Ramah","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Venessa","family":"Herminie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charlie","family":"Cox","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rita Fernandez","family":"Garda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","article-title":"Harrison's Principles of Internal Medicine","author":"Kasper DL","year":"2015","unstructured":"Kasper DL, Fauci AS, Hauser DL, Longo DL, Jameson LJ, Loscalzo J. Harrison's Principles of Internal Medicine. Kasper DL (ed): McGraw Hill Education, New York, NY; 2015."},{"key":"ref2","unstructured":"NICE Clinical Knowledge Summaries (CKS). Hyponatraemia. Incidence and prevalence. (2025). Accessed. September 2, 2025: https:\/\/cks.nice.org.uk\/topics\/hyponatraemia\/."},{"key":"ref3","article-title":"Davidson's Principles and Practice of Medicine","author":"Ralston SH","year":"2025","unstructured":"Ralston SH, Penman ID, Strachan MW, Hobson R. Davidson's Principles and Practice of Medicine. Elsevier Health Sciences, New York, NY; 2025."},{"key":"ref4","unstructured":"Heart failure with preserved ejection fraction. (2025). Accessed. October 10, 2025: https:\/\/bestpractice.bmj.com\/topics\/en-gb\/953."},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2020.9231","article-title":"Prognostic value of serum hyponatremia for outcomes in patients with heart failure with preserved ejection fraction: an observational cohort study","volume":"20","author":"Su Y","year":"2020","unstructured":"Su Y, Ma M, Zhang H, et al.. Prognostic value of serum hyponatremia for outcomes in patients with heart failure with preserved ejection fraction: an observational cohort study. Exp Ther Med. 2020, 20:101. 10.3892\/etm.2020.9231","journal-title":"Exp Ther Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1093\/ehjqcco\/qcae053","article-title":"Heart failure with preserved ejection fraction management: a systematic review of clinical practice guidelines and recommendations","volume":"10","author":"Mahmood A","year":"2024","unstructured":"Mahmood A, Dhall E, Primus CP, et al.. Heart failure with preserved ejection fraction management: a systematic review of clinical practice guidelines and recommendations. Eur Heart J Qual Care Clin Outcomes. 2024, 10:571-89. 10.1093\/ehjqcco\/qcae053","journal-title":"Eur Heart J Qual Care Clin Outcomes"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2022.07.023","article-title":"Hyponatremia in the emergency department","volume":"60","author":"Lindner G","year":"2022","unstructured":"Lindner G, Schwarz C, Haidinger M, Ravioli S. Hyponatremia in the emergency department. Am J Emerg Med. 2022, 60:1-8. 10.1016\/j.ajem.2022.07.023","journal-title":"Am J Emerg Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfs099","article-title":"Relationship of serum sodium concentration to mortality in a wide spectrum of heart failure patients with preserved and with reduced ejection fraction: an individual patient data meta-analysis(\u2020): Meta-Analysis Global Group in Chronic heart failure (MAGGIC)","volume":"14","author":"Rusinaru D","year":"2012","unstructured":"Rusinaru D, Tribouilloy C, Berry C, et al.. Relationship of serum sodium concentration to mortality in a wide spectrum of heart failure patients with preserved and with reduced ejection fraction: an individual patient data meta-analysis(\u2020): Meta-Analysis Global Group in Chronic heart failure (MAGGIC). Eur J Heart Fail. 2012, 14:1139-46. 10.1093\/eurjhf\/hfs099","journal-title":"Eur J Heart Fail"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.14797\/mdcj-13-1-40","article-title":"Hyponatremia in heart failure","volume":"13","author":"Adrogu\u00e9 HJ","year":"2017","unstructured":"Adrogu\u00e9 HJ. Hyponatremia in heart failure. Methodist Debakey Cardiovasc J. 2017, 13:40. 10.14797\/mdcj-13-1-40","journal-title":"Methodist Debakey Cardiovasc J"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6499346","article-title":"Hyponatremia and renal venous congestion in heart failure patients","volume":"2021","author":"Caraba A","year":"2021","unstructured":"Caraba A, Iurciuc S, Munteanu A, Iurciuc M. Hyponatremia and renal venous congestion in heart failure patients. Dis Markers. 2021, 2021:6499346. 10.1155\/2021\/6499346","journal-title":"Dis Markers"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2017-312084","article-title":"Hyponatraemia and its prognosis in acute heart failure is related to right ventricular dysfunction","volume":"104","author":"Lee H","year":"2018","unstructured":"Lee H, Lee SE, Park CS, et al.. Hyponatraemia and its prognosis in acute heart failure is related to right ventricular dysfunction. Heart. 2018, 104:1670-7. 10.1136\/heartjnl-2017-312084","journal-title":"Heart"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz641","article-title":"How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)","volume":"40","author":"Pieske B","year":"2019","unstructured":"Pieske B, Tsch\u00f6pe C, de Boer RA, et al.. How to diagnose heart failure with preserved ejection fraction: the HFA-PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC). Eur Heart J. 2019, 40:3297-317. 10.1093\/eurheartj\/ehz641","journal-title":"Eur Heart J"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.561423","article-title":"Influence of ejection fraction on cardiovascular outcomes in a broad spectrum of heart failure patients","volume":"112","author":"Solomon SD","year":"2005","unstructured":"Solomon SD, Anavekar N, Skali H, et al.. Influence of ejection fraction on cardiovascular outcomes in a broad spectrum of heart failure patients. Circulation. 2005, 112:3738-44. 10.1161\/CIRCULATIONAHA.105.561423","journal-title":"Circulation"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/s0735-1097(03)00185-2","article-title":"Outcomes in heart failure patients with preserved ejection fraction: mortality, readmission, and functional decline","volume":"41","author":"Smith GL","year":"2003","unstructured":"Smith GL, Masoudi FA, Vaccarino V, Radford MJ, Krumholz HM. Outcomes in heart failure patients with preserved ejection fraction: mortality, readmission, and functional decline. J Am Coll Cardiol. 2003, 41:1510-8. 10.1016\/s0735-1097(03)00185-2","journal-title":"J Am Coll Cardiol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.4250\/jcu.2011.19.4.169","article-title":"Use and limitations of E\/e' to assess left ventricular filling pressure by echocardiography","volume":"19","author":"Park JH","year":"2011","unstructured":"Park JH, Marwick TH. Use and limitations of E\/e' to assess left ventricular filling pressure by echocardiography. J Cardiovasc Ultrasound. 2011, 19:169-73. 10.4250\/jcu.2011.19.4.169","journal-title":"J Cardiovasc Ultrasound"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvac120","article-title":"Obesity and heart failure with preserved ejection fraction: new insights and pathophysiological targets","volume":"118","author":"Borlaug BA","year":"2023","unstructured":"Borlaug BA, Jensen MD, Kitzman DW, Lam CS, Obokata M, Rider OJ. Obesity and heart failure with preserved ejection fraction: new insights and pathophysiological targets. Cardiovasc Res. 2023, 118:3434-50. 10.1093\/cvr\/cvac120","journal-title":"Cardiovasc Res"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.2000","article-title":"\"Beer potomania\" - a syndrome of severe hyponatremia with unique pathophysiology: case studies and literature review","volume":"9","author":"Lodhi MU","year":"2017","unstructured":"Lodhi MU, Saleem TS, Kuzel AR, et al.. \"Beer potomania\" - a syndrome of severe hyponatremia with unique pathophysiology: case studies and literature review. Cureus. 2017, 9:e2000. 10.7759\/cureus.2000","journal-title":"Cureus"},{"key":"ref18","article-title":"Proteinuria","author":"Haider MZ","year":"2023","unstructured":"Haider MZ, Aslam A. Proteinuria. StatPearls Publishing, Treasure Island, FL; 2023."},{"key":"ref19","article-title":"Overview of the treatment of hyponatremia in adults","author":"Sterns RH","year":"2025","unstructured":"Sterns RH. Overview of the treatment of hyponatremia in adults. UpToDate. Forman JP (ed): Wolters Kluwer, Philadelphia, NY; 2025."},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2007.09.001","article-title":"Hyponatremia treatment guidelines 2007: expert panel recommendations","volume":"120","author":"Verbalis JG","year":"2007","unstructured":"Verbalis JG, Goldsmith SR, Greenberg A, Schrier RW, Sterns RH. Hyponatremia treatment guidelines 2007: expert panel recommendations. Am J Med. 2007, 120:S1-21. 10.1016\/j.amjmed.2007.09.001","journal-title":"Am J Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/415449-a-case-of-severe-hyponatremia-unmasking-borderline-heart-failure-with-preserved-ejection-fraction-with-right-ventricular-dysfunction","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T21:50:36Z","timestamp":1760997036000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/415449-a-case-of-severe-hyponatremia-unmasking-borderline-heart-failure-with-preserved-ejection-fraction-with-right-ventricular-dysfunction"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,20]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.95007","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10,20]]}}}