{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T07:23:03Z","timestamp":1765610583947,"version":"build-2065373602"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,28]]},"DOI":"10.7759\/cureus.95593","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T14:28:54Z","timestamp":1761661734000},"source":"Crossref","is-referenced-by-count":1,"title":["Everolimus-Induced Pulmonary Toxicity in a Lung Transplant Recipient: A Case Report"],"prefix":"10.7759","author":[{"given":"Fabio","family":"Var\u00f3n-Vega","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria C","family":"Martinez-Ayala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camilo","family":"Rodr\u00edguez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Mendoza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis J","family":"Tellez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Tuta-Quintero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2021.07.005","article-title":"Consensus document for the selection of lung transplant candidates: an update from the International Society for Heart and Lung Transplantation","volume":"40","author":"Leard LE","year":"2021","unstructured":"Leard LE, Holm AM, Valapour M, et al.. Consensus document for the selection of lung transplant candidates: an update from the International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 2021, 40:1349-79. 10.1016\/j.healun.2021.07.005","journal-title":"J Heart Lung Transplant"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2019.03.009","article-title":"Chronic lung allograft dysfunction: definition, diagnostic criteria, and approaches to treatment\u2015a consensus report from the Pulmonary Council of the ISHLT","volume":"38","author":"Verleden GM","year":"2019","unstructured":"Verleden GM, Glanville AR, Lease ED, et al.. Chronic lung allograft dysfunction: definition, diagnostic criteria, and approaches to treatment\u2015a consensus report from the Pulmonary Council of the ISHLT. J Heart Lung Transplant. 2019, 38:493-503. 10.1016\/j.healun.2019.03.009","journal-title":"J Heart Lung Transplant"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/phar.2718","article-title":"Consensus recommendations for use of maintenance immunosuppression in solid organ transplantation: endorsed by the American College of Clinical Pharmacy, American Society of Transplantation, and International Society for Heart and Lung Transplantation: an executive summary","volume":"42","author":"Nelson J","year":"2022","unstructured":"Nelson J, Alvey N, Bowman L, et al.. Consensus recommendations for use of maintenance immunosuppression in solid organ transplantation: endorsed by the American College of Clinical Pharmacy, American Society of Transplantation, and International Society for Heart and Lung Transplantation: an executive summary. Pharmacotherapy. 2022, 42:594-8. 10.1002\/phar.2718","journal-title":"Pharmacotherapy"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/omcr\/omy008","article-title":"Everolimus induced pneumonitis in a lung transplant recipient","volume":"2018","author":"Arunachalam A","year":"2018","unstructured":"Arunachalam A, Ali SR, Wakefield BJ, Lane CR, Mehta AC. Everolimus induced pneumonitis in a lung transplant recipient. Oxf Med Case Rep. 2018, 2018:omy008. 10.1093\/omcr\/omy008","journal-title":"Oxf Med Case Rep"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/305931","article-title":"Interstitial lung disease associated with mTOR inhibitors in solid organ transplant recipients: results from a large phase III clinical trial program of everolimus and review of the literature","volume":"2014","author":"Lopez P","year":"2014","unstructured":"Lopez P, Kohler S, Dimri S. Interstitial lung disease associated with mTOR inhibitors in solid organ transplant recipients: results from a large phase III clinical trial program of everolimus and review of the literature. J Transplant. 2014, 2014:305931. 10.1155\/2014\/305931","journal-title":"J Transplant"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2012.03.012","article-title":"Pneumonitis associated with mTOR inhibitors therapy in patients with metastatic renal cell carcinoma: incidence, radiographic findings and correlation with clinical outcome","volume":"48","author":"Dabydeen DA","year":"2012","unstructured":"Dabydeen DA, Jagannathan JP, Ramaiya N, et al.. Pneumonitis associated with mTOR inhibitors therapy in patients with metastatic renal cell carcinoma: incidence, radiographic findings and correlation with clinical outcome. Eur J Cancer. 2012, 48:1519-24. 10.1016\/j.ejca.2012.03.012","journal-title":"Eur J Cancer"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2012.705019","article-title":"Incidence and risk of pulmonary toxicity in patients treated with mTOR inhibitors for malignancy. A meta-analysis of published trials","volume":"51","author":"Iacovelli R","year":"2012","unstructured":"Iacovelli R, Palazzo A, Mezi S, Morano F, Naso G, Cortesi E. Incidence and risk of pulmonary toxicity in patients treated with mTOR inhibitors for malignancy. A meta-analysis of published trials. Acta Oncol. 2012, 51:873-9. 10.3109\/0284186X.2012.705019","journal-title":"Acta Oncol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mds115","article-title":"Incidence and management of mTOR inhibitor-associated pneumonitis in patients with metastatic renal cell carcinoma","volume":"23","author":"Albiges L","year":"2012","unstructured":"Albiges L, Chamming's F, Duclos B, Stern M, Motzer RJ, Ravaud A, Camus P. Incidence and management of mTOR inhibitor-associated pneumonitis in patients with metastatic renal cell carcinoma. Ann Oncol. 2012, 23:1943-53. 10.1093\/annonc\/mds115","journal-title":"Ann Oncol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200911-1720OC","article-title":"Noninfectious pneumonitis after everolimus therapy for advanced renal cell carcinoma","volume":"182","author":"White DA","year":"2010","unstructured":"White DA, Camus P, Endo M, et al.. Noninfectious pneumonitis after everolimus therapy for advanced renal cell carcinoma. Am J Respir Crit Care Med. 2010, 182:396-403. 10.1164\/rccm.200911-1720OC","journal-title":"Am J Respir Crit Care Med"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2021203427","article-title":"Chest CT diagnosis and clinical management of drug-related pneumonitis in patients receiving molecular targeting agents and immune checkpoint inhibitors: a position paper from the Fleischner Society","volume":"298","author":"Johkoh T","year":"2021","unstructured":"Johkoh T, Lee KS, Nishino M, et al.. Chest CT diagnosis and clinical management of drug-related pneumonitis in patients receiving molecular targeting agents and immune checkpoint inhibitors: a position paper from the Fleischner Society. Radiology. 2021, 298:550-66. 10.1148\/radiol.2021203427","journal-title":"Radiology"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.52.8588","article-title":"Granuloma-forming interstitial pneumonia occurring one year after the start of everolimus therapy","volume":"52","author":"Saito Y","year":"2013","unstructured":"Saito Y, Kunugi S, Suzuki Y, et al.. Granuloma-forming interstitial pneumonia occurring one year after the start of everolimus therapy. Intern Med. 2013, 52:263-7. 10.2169\/internalmedicine.52.8588","journal-title":"Intern Med"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02292-2019","article-title":"Late-onset \"acute fibrinous and organising pneumonia\" impairs long-term lung allograft function and survival","volume":"56","author":"Vanstapel A","year":"2020","unstructured":"Vanstapel A, Verleden SE, Weynand B, et al.. Late-onset \"acute fibrinous and organising pneumonia\" impairs long-term lung allograft function and survival. Eur Respir J. 2020, 56:1902292. 10.1183\/13993003.02292-2019","journal-title":"Eur Respir J"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154","article-title":"A method for estimating the probability of adverse drug reactions","volume":"30","author":"Naranjo CA","year":"1981","unstructured":"Naranjo CA, Busto U, Sellers EM, et al.. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther. 1981, 30:239-45. 10.1038\/clpt.1981.154","journal-title":"Clin Pharmacol Ther"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra064928","article-title":"Infection in solid-organ transplant recipients","volume":"357","author":"Fishman JA","year":"2007","unstructured":"Fishman JA. Infection in solid-organ transplant recipients. N Engl J Med. 2007, 357:2601-14. 10.1056\/NEJMra064928","journal-title":"N Engl J Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/406186-everolimus-induced-pulmonary-toxicity-in-a-lung-transplant-recipient-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T14:28:55Z","timestamp":1761661735000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/406186-everolimus-induced-pulmonary-toxicity-in-a-lung-transplant-recipient-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,28]]},"references-count":14,"URL":"https:\/\/doi.org\/10.7759\/cureus.95593","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10,28]]}}}