{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T12:32:00Z","timestamp":1780749120434,"version":"3.54.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,4]]},"DOI":"10.7759\/cureus.96059","type":"journal-article","created":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T10:37:25Z","timestamp":1762252645000},"source":"Crossref","is-referenced-by-count":1,"title":["Prospective Randomised Control Study to Evaluate the Effectiveness of Hypochlorous Acid as a Peritoneal Lavage Agent to Prevent Surgical Site Infection After Exploratory Laparotomy for Perforation Peritonitis"],"prefix":"10.7759","author":[{"given":"Mayank","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishna P","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richa","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2005.09.006","article-title":"Surgical site infections","volume":"85","author":"Barie PS","year":"2005","unstructured":"Barie PS, Eachempati SR. Surgical site infections. Surg Clin North Am. 2005, 85:1115-1135. 10.1016\/j.suc.2005.09.006","journal-title":"Surg Clin North Am"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1086\/501620","article-title":"Guideline for prevention of surgical site infection, 1999","volume":"20","author":"Mangram AJ","year":"1999","unstructured":"Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR, Hospital Infection Control Practices Advisory Committee. Guideline for prevention of surgical site infection, 1999. Infect Control Hosp Epidemiol. 1999, 20:247-280. 10.1086\/501620","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref3","article-title":"Bailey & Love's Short Practice of Surgery","year":"2023","unstructured":"Bailey & Love's Short Practice of Surgery. O\u2019Connell PR, McCaskie AW, Sayers RD (ed). CRC Press, 2023."},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2016.10.029","article-title":"American College of Surgeons and Surgical Infection Society: Surgical Site Infection Guidelines, 2016 Update","volume":"224","author":"Ban KA","year":"2017","unstructured":"Ban KA, Minei JP, Laronga C, et al.. American College of Surgeons and Surgical Infection Society: Surgical Site Infection Guidelines, 2016 Update. J Am Coll Surg. 2017, 224:59-74. 10.1016\/j.jamcollsurg.2016.10.029","journal-title":"J Am Coll Surg"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/896297","article-title":"The prevention of surgical site infection in elective colon surgery","volume":"2013","author":"Fry DE","year":"2013","unstructured":"Fry DE. The prevention of surgical site infection in elective colon surgery. Scientifica (Cairo). 2013, 2013:896297. 10.1155\/2013\/896297","journal-title":"Scientifica (Cairo)"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2006.7.s1-7","article-title":"Risk factors for surgical site infection","volume":"7","author":"Cheadle WG","year":"2006","unstructured":"Cheadle WG. Risk factors for surgical site infection. Surg Infect (Larchmt). 2006, 7:S7-S11. 10.1089\/sur.2006.7.s1-7","journal-title":"Surg Infect (Larchmt)"},{"key":"ref7","article-title":"Statement on ASA Physical Status Classification System","author":"American Society of Anesthesiologists","year":"2020","unstructured":"American Society of Anesthesiologists. Statement on ASA Physical Status Classification System. American Society of Anesthesiologists, 2020."},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800600817","article-title":"Transection of the oesophagus for bleeding oesophageal varices","volume":"60","author":"Pugh RN","year":"1973","unstructured":"Pugh RN, Murray-Lyon IM, Dawson JL, Pietroni MC, Williams R. Transection of the oesophagus for bleeding oesophageal varices. Br J Surg. 1973, 60:646-649. 10.1002\/bjs.1800600817","journal-title":"Br J Surg"},{"key":"ref9","article-title":"Research Randomizer (Version 4.0) [Computer program]","author":"Urbaniak GC","year":"2013","unstructured":"Urbaniak GC, Plous S. Research Randomizer (Version 4.0) [Computer program]. 2013."},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1093\/bjsopen\/zrae121","article-title":"Effect of peritoneal and wound lavage with super-oxidized solution on surgical-site infection after open appendicectomy in perforated appendicitis (PLaSSo): randomized clinical trial","volume":"8","author":"Sellappan H","year":"2024","unstructured":"Sellappan H, Alagoo D, Loo C, Vijian K, Sibin R, Chuah JA. Effect of peritoneal and wound lavage with super-oxidized solution on surgical-site infection after open appendicectomy in perforated appendicitis (PLaSSo): randomized clinical trial. BJS Open. 2024, 8:zrae121. 10.1093\/bjsopen\/zrae121","journal-title":"BJS Open"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-014-1050-x","article-title":"Efficacy and safety of strong acid electrolyzed water for peritoneal lavage to prevent surgical site infection in patients with perforated appendicitis","volume":"45","author":"Kubota A","year":"2015","unstructured":"Kubota A, Goda T, Tsuru T, et al.. Efficacy and safety of strong acid electrolyzed water for peritoneal lavage to prevent surgical site infection in patients with perforated appendicitis. Surg Today. 2015, 45:876-879. 10.1007\/s00595-014-1050-x","journal-title":"Surg Today"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2023.7985","article-title":"Intraoperative wound irrigation for the prevention of surgical site infection after laparotomy: a randomized clinical trial by CHIR-Net","volume":"159","author":"Mueller TC","year":"2024","unstructured":"Mueller TC, Kehl V, Dimpel R, et al.. Intraoperative wound irrigation for the prevention of surgical site infection after laparotomy: a randomized clinical trial by CHIR-Net. JAMA Surg. 2024, 159:484-492. 10.1001\/jamasurg.2023.7985","journal-title":"JAMA Surg"},{"key":"ref13","article-title":"Comparative evaluation of intra-operative peritoneal lavage with super oxidized solution and normal saline in peritonitis cases; randomized controlled trial","volume":"11","author":"Singal R","year":"2016","unstructured":"Singal R, Dhar S, Zaman M, Singh B, Singh V, Sethi S. Comparative evaluation of intra-operative peritoneal lavage with super oxidized solution and normal saline in peritonitis cases; randomized controlled trial. Maedica (Bucur). 2016, 11:277-285.","journal-title":"Maedica (Bucur)"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1086\/501572","article-title":"The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra costs","volume":"20","author":"Kirkland KB","year":"1999","unstructured":"Kirkland KB, Briggs JP, Trivette SL, Wilkinson WE, Sexton DJ. The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol. 1999, 20:725-730. 10.1086\/501572","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.33545\/surgery.2021.v5.i2f.718","article-title":"Incidence of surgical site infections after emergency laparotomy for perforation peritonitis","volume":"5","author":"Akter B","year":"2021","unstructured":"Akter B, Anwar A, Tabibul Islam M, et al.. Incidence of surgical site infections after emergency laparotomy for perforation peritonitis. Int J Surg Sci. 2021, 5:335-338. 10.33545\/surgery.2021.v5.i2f.718","journal-title":"Int J Surg Sci"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2016.12.016","article-title":"World Health Organization: global guidelines for the prevention of surgical site infection","volume":"95","author":"Leaper DJ","year":"2017","unstructured":"Leaper DJ, Edmiston CE. World Health Organization: global guidelines for the prevention of surgical site infection. J Hosp Infect. 2017, 95:135-136. 10.1016\/j.jhin.2016.12.016","journal-title":"J Hosp Infect"},{"key":"ref17","unstructured":"Centers for Disease Control and Prevention (CDC). Procedure-associated module. surgical site infection (SSI) event. NHSN. (2023). Accessed: October 30, 2025: https:\/\/www.cdc.gov\/nhsn\/.."},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.F.01515","article-title":"Risk factors for surgical site infection following orthopaedic spinal operations","volume":"90","author":"Olsen MA","year":"2008","unstructured":"Olsen MA, Nepple JJ, Riew KD, Lenke LG, Bridwell KH, Mayfield J, Fraser VJ. Risk factors for surgical site infection following orthopaedic spinal operations. J Bone Joint Surg Am. 2008, 90:62-69. 10.2106\/JBJS.F.01515","journal-title":"J Bone Joint Surg Am"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.12.1.147","article-title":"Antiseptics and disinfectants: activity, action, and resistance","volume":"12","author":"McDonnell G","year":"1999","unstructured":"McDonnell G, Russell AD. Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev. 1999, 12:147-179. 10.1128\/CMR.12.1.147","journal-title":"Clin Microbiol Rev"},{"key":"ref20","unstructured":"World Health Organization. 2018. Global guidelines for the prevention of surgical site infection. (2018). Accessed: October 30, 2025: https:\/\/www.who.int\/publications\/i\/item\/9789241550475."}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/416983-prospective-randomised-control-study-to-evaluate-the-effectiveness-of-hypochlorous-acid-as-a-peritoneal-lavage-agent-to-prevent-surgical-site-infection-after-exploratory-laparotomy-for-perforation-peritonitis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T10:37:29Z","timestamp":1762252649000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/416983-prospective-randomised-control-study-to-evaluate-the-effectiveness-of-hypochlorous-acid-as-a-peritoneal-lavage-agent-to-prevent-surgical-site-infection-after-exploratory-laparotomy-for-perforation-peritonitis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,4]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.96059","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11,4]]}}}