{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T13:26:21Z","timestamp":1784899581455,"version":"3.55.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,10]]},"DOI":"10.7759\/cureus.96473","type":"journal-article","created":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T11:41:51Z","timestamp":1762774911000},"source":"Crossref","is-referenced-by-count":1,"title":["A Review of Susceptibility Factors for Colibactin-Associated Colorectal Cancer in African Populations"],"prefix":"10.7759","author":[{"given":"Olurotimi J","family":"Badero","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onyinye I","family":"Ikedionwu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Ajayi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abayomi V","family":"Jemiseye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms8081233","article-title":"Rapid detection and antibiotic susceptibility of uropathogenic escherichia coli by flow cytometry","volume":"8","author":"Velican AM","year":"2020","unstructured":"Velican AM, M\u0103ru\u0163escu L, Kamerzan C, Cristea VC, Banu O, Borcan E, Chifiriuc MC. Rapid detection and antibiotic susceptibility of uropathogenic escherichia coli by flow cytometry. Microorganisms. 2020, 8:1233. 10.3390\/microorganisms8081233","journal-title":"Microorganisms"},{"key":"ref2","unstructured":"International Agency for Research on Cancer (IARC). Global Cancer Observatory. (2024). Accessed: 2024: https:\/\/gco.iarc.who.int\/en."},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.22838","article-title":"Prevalence of pks gene cluster and characteristics of Klebsiella pneumoniae-induced bloodstream infections","volume":"33","author":"Lan Y","year":"2019","unstructured":"Lan Y, Zhou M, Jian Z, Yan Q, Wang S, Liu W. Prevalence of pks gene cluster and characteristics of Klebsiella pneumoniae-induced bloodstream infections. J Clin Lab Anal. 2019, 33:e22838. 10.1002\/jcla.22838","journal-title":"J Clin Lab Anal"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2015.75","article-title":"POLE and POLD1 mutations in 529 kindred with familial colorectal cancer and\/or polyposis: review of reported cases and recommendations for genetic testing and surveillance","volume":"18","author":"Bellido F","year":"2016","unstructured":"Bellido F, Pineda M, Aiza G, et al.. POLE and POLD1 mutations in 529 kindred with familial colorectal cancer and\/or polyposis: review of reported cases and recommendations for genetic testing and surveillance. Genet Med. 2016, 18:325-32. 10.1038\/gim.2015.75","journal-title":"Genet Med"},{"key":"ref5","article-title":"Genomics of Lynch syndrome and Constitutional mismatch repair deficiency syndrome [Thesis]","author":"Lamola L","year":"2018","unstructured":"Lamola L. Genomics of Lynch syndrome and Constitutional mismatch repair deficiency syndrome [Thesis]. University of Cape Town, Cape Town, South Africa; 2018."},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2022.02.002","article-title":"Hereditary colorectal cancer","volume":"36","author":"Hampel H","year":"2022","unstructured":"Hampel H, Kalady MF, Pearlman R, Stanich PP. Hereditary colorectal cancer. Hematol Oncol Clin North Am. 2022, 36:429-47. 10.1016\/j.hoc.2022.02.002","journal-title":"Hematol Oncol Clin North Am"},{"key":"ref7","article-title":"Determination of virulence determinants of Escherichia coli strains isolated from patients with colorectal cancer compared to the healthy subjects","volume":"12","author":"Zarei O","year":"2019","unstructured":"Zarei O, Arabestan MR, Majlesi A, Mohammadi Y, Alikhani MY. Determination of virulence determinants of Escherichia coli strains isolated from patients with colorectal cancer compared to the healthy subjects. Gastroenterol Hepatol Bed Bench. 2019, 12:52-9.","journal-title":"Gastroenterol Hepatol Bed Bench"},{"key":"ref8","article-title":"World Cancer Report 2014. Geneva, Switzerland: World Health Organization, International Agency for Research on Cancer, WHO Press, 2015","unstructured":"World Cancer Report 2014. Stewart BW, Wild CP (ed). International Agency for Research on Cancer, Lyons,, France; https:\/\/publications.iarc.who.int\/Non-Series-Publications\/World-Cancer-Reports\/World-Cancer-Report-2014."},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-16-3472","article-title":"Locoregional effects of microbiota in a preclinical model of colon carcinogenesis","volume":"77","author":"Tomkovich S","year":"2017","unstructured":"Tomkovich S, Yang Y, Winglee K, et al.. Locoregional effects of microbiota in a preclinical model of colon carcinogenesis. Cancer Res. 2017, 77:2620-32. 10.1158\/0008-5472.CAN-16-3472","journal-title":"Cancer Res"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v24.i22.2327","article-title":"Microbial markers in colorectal cancer detection and\/or prognosis","volume":"24","author":"Vill\u00e9ger R","year":"2018","unstructured":"Vill\u00e9ger R, Lop\u00e8s A, Veziant J, et al.. Microbial markers in colorectal cancer detection and\/or prognosis. World J Gastroenterol. 2018, 24:2327-47. 10.3748\/wjg.v24.i22.2327","journal-title":"World J Gastroenterol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S183283","article-title":"Bacterial profile, antibiotic resistance pattern and associated factors among cancer patients at University of Gondar Hospital, Northwest Ethiopia","volume":"11","author":"Fentie A","year":"2018","unstructured":"Fentie A, Wondimeneh Y, Balcha A, Amsalu A, Adankie BT. Bacterial profile, antibiotic resistance pattern and associated factors among cancer patients at University of Gondar Hospital, Northwest Ethiopia. Infect Drug Resist. 2018, 11:2169-78. 10.2147\/IDR.S183283","journal-title":"Infect Drug Resist"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-10-161","article-title":"Escherichia coli phylogenetic group determination and its application in the identification of the major animal source of fecal contamination","volume":"10","author":"Carlos C","year":"2010","unstructured":"Carlos C, Pires MM, Stoppe NC, et al.. Escherichia coli phylogenetic group determination and its application in the identification of the major animal source of fecal contamination. BMC Microbiol. 2010, 10:161. 10.1186\/1471-2180-10-161","journal-title":"BMC Microbiol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s10689-019-00145-5","article-title":"Novel candidates in early-onset familial colorectal cancer","volume":"19","author":"Jansen AM","year":"2020","unstructured":"Jansen AM, Ghosh P, Dakal TC, Slavin TP, Boland CR, Goel A. Novel candidates in early-onset familial colorectal cancer. Fam Cancer. 2020, 19:1-10. 10.1007\/s10689-019-00145-5","journal-title":"Fam Cancer"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-017-3599-4","article-title":"A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America","volume":"17","author":"Rossi BM","year":"2017","unstructured":"Rossi BM, Palmero EI, L\u00f3pez-Kostner F, et al.. A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America. BMC Cancer. 2017, 17:623. 10.1186\/s12885-017-3599-4","journal-title":"BMC Cancer"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3390\/toxins13050346","article-title":"Shining a light on colibactin biology","volume":"13","author":"Dougherty MW","year":"2021","unstructured":"Dougherty MW, Jobin C. Shining a light on colibactin biology. Toxins (Basel). 2021, 13:346. 10.3390\/toxins13050346","journal-title":"Toxins (Basel)"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2019.04.007","article-title":"Unveiling the mutational mechanism of the bacterial genotoxin colibactin in colorectal cancer","volume":"74","author":"Thakur BK","year":"2019","unstructured":"Thakur BK, Malais\u00e9 Y, Martin A. Unveiling the mutational mechanism of the bacterial genotoxin colibactin in colorectal cancer. Mol Cell. 2019, 74:227-9. 10.1016\/j.molcel.2019.04.007","journal-title":"Mol Cell"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660","article-title":"Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung H","year":"2021","unstructured":"Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021, 71:209-49. 10.3322\/caac.21660","journal-title":"CA Cancer J Clin"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.12433","article-title":"Obesity and the nutrition transition in Sub-Saharan Africa","volume":"1311","author":"Steyn NP","year":"2014","unstructured":"Steyn NP, McHiza ZJ. Obesity and the nutrition transition in Sub-Saharan Africa. Ann N Y Acad Sci. 2014, 1311:88-101. 10.1111\/nyas.12433","journal-title":"Ann N Y Acad Sci"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/415137-a-review-of-susceptibility-factors-for-colibactin-associated-colorectal-cancer-in-african-populations","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T11:41:52Z","timestamp":1762774912000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/415137-a-review-of-susceptibility-factors-for-colibactin-associated-colorectal-cancer-in-african-populations"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,10]]},"references-count":18,"URL":"https:\/\/doi.org\/10.7759\/cureus.96473","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11,10]]}}}