{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T03:32:50Z","timestamp":1783567970443,"version":"3.55.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,10]]},"DOI":"10.7759\/cureus.96526","type":"journal-article","created":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T06:59:01Z","timestamp":1762844341000},"source":"Crossref","is-referenced-by-count":1,"title":["Association of the Systemic Immune-Inflammatory Index, Neutrophil-to-Lymphocyte Ratio, and Platelet-to-Lymphocyte Ratio in the Differentiation of Chronic Otitis Media: A Prospective Observational Analytical Study"],"prefix":"10.7759","author":[{"given":"Shaila","family":"Sidam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjan K","family":"Sahoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aparna G","family":"Chavan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivek K","family":"Bharti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s00232-013-9561-8","article-title":"Serum myeloperoxidase activity, total antioxidant capacity and nitric oxide levels in patients with chronic otitis media","volume":"246","author":"Gar\u00e7a MF","year":"2013","unstructured":"Gar\u00e7a MF, Aslan M, Tuna B, Kozan A, Cankaya H. Serum myeloperoxidase activity, total antioxidant capacity and nitric oxide levels in patients with chronic otitis media. J Membr Biol. 2013, 246:519-24. 10.1007\/s00232-013-9561-8","journal-title":"J Membr Biol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2403-6","article-title":"Activation of the EGFR\/Akt\/NF-\u03baB\/cyclinD1 survival signaling pathway in human cholesteatoma epithelium","volume":"271","author":"Liu W","year":"2014","unstructured":"Liu W, Yin T, Ren J, Li L, Xiao Z, Chen X, Xie D. Activation of the EGFR\/Akt\/NF-\u03baB\/cyclinD1 survival signaling pathway in human cholesteatoma epithelium. Eur Arch Otorhinolaryngol. 2014, 271:265-73. 10.1007\/s00405-013-2403-6","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25834","article-title":"Acquired cholesteatoma epithelial hyperproliferation: Roles of cell proliferation signal pathways","volume":"126","author":"Xie S","year":"2016","unstructured":"Xie S, Xiang Y, Wang X, Ren H, Yin T, Ren J, Liu W. Acquired cholesteatoma epithelial hyperproliferation: Roles of cell proliferation signal pathways. Laryngoscope. 2016, 126:1923-30. 10.1002\/lary.25834","journal-title":"Laryngoscope"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/1755-7682-5-2","article-title":"Neutrophil lymphocyte ratio as a measure of systemic inflammation in prevalent chronic diseases in Asian population","volume":"5","author":"Imtiaz F","year":"2012","unstructured":"Imtiaz F, Shafique K, Mirza SS, Ayoob Z, Vart P, Rao S. Neutrophil lymphocyte ratio as a measure of systemic inflammation in prevalent chronic diseases in Asian population. Int Arch Med. 2012, 5:2. 10.1186\/1755-7682-5-2","journal-title":"Int Arch Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-024-01959-5","article-title":"Systemic immune inflammation index with all-cause and cause-specific mortality: a meta-analysis","volume":"73","author":"Li W","year":"2024","unstructured":"Li W, Wang X, Diao H, et al.. Systemic immune inflammation index with all-cause and cause-specific mortality: a meta-analysis. Inflamm Res. 2024, 73:2199-216. 10.1007\/s00011-024-01959-5","journal-title":"Inflamm Res"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.2217\/imt-2022-0133","article-title":"Systemic immune-inflammation index predicts prognosis of cancer immunotherapy: systemic review and meta-analysis","volume":"14","author":"Tian BW","year":"2022","unstructured":"Tian BW, Yang YF, Yang CC, et al.. Systemic immune-inflammation index predicts prognosis of cancer immunotherapy: systemic review and meta-analysis. Immunotherapy. 2022, 14:1481-96. 10.2217\/imt-2022-0133","journal-title":"Immunotherapy"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.2478\/jccm-2022-0013","article-title":"Predictive value of systemic immune-inflammation index in determining mortality in COVID-19 patients","volume":"8","author":"Karaaslan T","year":"2022","unstructured":"Karaaslan T, Karaaslan E. Predictive value of systemic immune-inflammation index in determining mortality in COVID-19 patients. J Crit Care Med (Targu Mures). 2022, 8:156-64. 10.2478\/jccm-2022-0013","journal-title":"J Crit Care Med (Targu Mures)"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S446364","article-title":"Relationship between systemic immune-inflammation index and risk of respiratory failure and death in COPD: a retrospective cohort study based on the MIMIC-IV database","volume":"19","author":"Zhang Y","year":"2024","unstructured":"Zhang Y, Tan X, Hu S, Cui Z, Chen W. Relationship between systemic immune-inflammation index and risk of respiratory failure and death in COPD: a retrospective cohort study based on the MIMIC-IV database. Int J Chron Obstruct Pulmon Dis. 2024, 19:459-73. 10.2147\/COPD.S446364","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s10238-023-01029-w","article-title":"Association between admission systemic immune-inflammation index and mortality in critically ill patients with sepsis: a retrospective cohort study based on MIMIC-IV database","volume":"23","author":"Jiang D","year":"2023","unstructured":"Jiang D, Bian T, Shen Y, Huang Z. Association between admission systemic immune-inflammation index and mortality in critically ill patients with sepsis: a retrospective cohort study based on MIMIC-IV database. Clin Exp Med. 2023, 23:3641-50. 10.1007\/s10238-023-01029-w","journal-title":"Clin Exp Med"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i34.6261","article-title":"Systemic immune-inflammation index for predicting prognosis of colorectal cancer","volume":"23","author":"Chen JH","year":"2017","unstructured":"Chen JH, Zhai ET, Yuan YJ, et al.. Systemic immune-inflammation index for predicting prognosis of colorectal cancer. World J Gastroenterol. 2017, 23:6261-72. 10.3748\/wjg.v23.i34.6261","journal-title":"World J Gastroenterol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-024-03849-4","article-title":"Systemic immune-inflammation index as a novel predictor of major adverse cardiovascular events in patients undergoing percutaneous coronary intervention: a meta-analysis of cohort studies","volume":"24","author":"Zhang C","year":"2024","unstructured":"Zhang C, Li M, Liu L, et al.. Systemic immune-inflammation index as a novel predictor of major adverse cardiovascular events in patients undergoing percutaneous coronary intervention: a meta-analysis of cohort studies. BMC Cardiovasc Disord. 2024, 24:189. 10.1186\/s12872-024-03849-4","journal-title":"BMC Cardiovasc Disord"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-023-02890-y","article-title":"The relationship between systemic inflammation index, systemic immune-inflammatory index, and inflammatory prognostic index and 90-day outcomes in acute ischemic stroke patients treated with intravenous thrombolysis","volume":"20","author":"Ma F","year":"2023","unstructured":"Ma F, Li L, Xu L, et al.. The relationship between systemic inflammation index, systemic immune-inflammatory index, and inflammatory prognostic index and 90-day outcomes in acute ischemic stroke patients treated with intravenous thrombolysis. J Neuroinflammation. 2023, 20:220. 10.1186\/s12974-023-02890-y","journal-title":"J Neuroinflammation"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00012.2018","article-title":"The neutrophil's role during health and disease","volume":"99","author":"Liew PX","year":"2019","unstructured":"Liew PX, Kubes P. The neutrophil's role during health and disease. Physiol Rev. 2019, 99:1223-48. 10.1152\/physrev.00012.2018","journal-title":"Physiol Rev"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-020-0412-0","article-title":"Neutrophil chemoattractant receptors in health and disease: double-edged swords","volume":"17","author":"Metzemaekers M","year":"2020","unstructured":"Metzemaekers M, Gouwy M, Proost P. Neutrophil chemoattractant receptors in health and disease: double-edged swords. Cell Mol Immunol. 2020, 17:433-50. 10.1038\/s41423-020-0412-0","journal-title":"Cell Mol Immunol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-016-2335-5","article-title":"What is the normal value of the neutrophil-to-lymphocyte ratio?","volume":"10","author":"Forget P","year":"2017","unstructured":"Forget P, Khalifa C, Defour JP, Latinne D, Van Pel MC, De Kock M. What is the normal value of the neutrophil-to-lymphocyte ratio?. BMC Res Notes. 2017, 10:12. 10.1186\/s13104-016-2335-5","journal-title":"BMC Res Notes"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.4149\/BLL_2021_078","article-title":"Neutrophil-to-lymphocyte ratio, past, present and future perspectives","volume":"122","author":"Zahorec R","year":"2021","unstructured":"Zahorec R. Neutrophil-to-lymphocyte ratio, past, present and future perspectives. Bratisl Lek Listy. 2021, 122:474-88. 10.4149\/BLL_2021_078","journal-title":"Bratisl Lek Listy"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-020-01817-1","article-title":"Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies","volume":"18","author":"Cupp MA","year":"2020","unstructured":"Cupp MA, Cariolou M, Tzoulaki I, Aune D, Evangelou E, Berlanga-Taylor AJ. Neutrophil to lymphocyte ratio and cancer prognosis: an umbrella review of systematic reviews and meta-analyses of observational studies. BMC Med. 2020, 18:360. 10.1186\/s12916-020-01817-1","journal-title":"BMC Med"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2019.10.023","article-title":"Prognostic value of neutrophil-to-lymphocyte ratio in sepsis: a meta-analysis","volume":"38","author":"Huang Z","year":"2020","unstructured":"Huang Z, Fu Z, Huang W, Huang K. Prognostic value of neutrophil-to-lymphocyte ratio in sepsis: a meta-analysis. Am J Emerg Med. 2020, 38:641-7. 10.1016\/j.ajem.2019.10.023","journal-title":"Am J Emerg Med"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/dju124","article-title":"Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis","volume":"106","author":"Templeton AJ","year":"2014","unstructured":"Templeton AJ, McNamara MG, \u0160eruga B, et al.. Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis. J Natl Cancer Inst. 2014, 106:dju124. 10.1093\/jnci\/dju124","journal-title":"J Natl Cancer Inst"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-018-0649-4","article-title":"Neutrophil-to-lymphocyte ratio in acute cerebral hemorrhage: a system review","volume":"10","author":"Lattanzi S","year":"2019","unstructured":"Lattanzi S, Brigo F, Trinka E, Cagnetti C, Di Napoli M, Silvestrini M. Neutrophil-to-lymphocyte ratio in acute cerebral hemorrhage: a system review. Transl Stroke Res. 2019, 10:137-45. 10.1007\/s12975-018-0649-4","journal-title":"Transl Stroke Res"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.eprac.2021.11.083","article-title":"Is the neutrophil-to-lymphocyte ratio an exceptional indicator for metabolic syndrome disease and outcomes?","volume":"28","author":"Hashemi Moghanjoughi P","year":"2022","unstructured":"Hashemi Moghanjoughi P, Neshat S, Rezaei A, Heshmat-Ghahdarijani K. Is the neutrophil-to-lymphocyte ratio an exceptional indicator for metabolic syndrome disease and outcomes?. Endocr Pract. 2022, 28:342-8. 10.1016\/j.eprac.2021.11.083","journal-title":"Endocr Pract"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1080\/03007995.2023.2174327","article-title":"Neutrophil-lymphocyte ratio, monocyte-lymphocyte ratio, and platelet-lymphocyte ratio in stroke-associated pneumonia: a systematic review and meta-analysis","volume":"39","author":"Zawiah M","year":"2023","unstructured":"Zawiah M, Hayat Khan A, Abu Farha R, Usman A, Bitar AN. Neutrophil-lymphocyte ratio, monocyte-lymphocyte ratio, and platelet-lymphocyte ratio in stroke-associated pneumonia: a systematic review and meta-analysis. Curr Med Res Opin. 2023, 39:475-82. 10.1080\/03007995.2023.2174327","journal-title":"Curr Med Res Opin"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2023023702","article-title":"Thrombocytosis","volume":"143","author":"Liaskas A","year":"2024","unstructured":"Liaskas A, Vassilakopoulos TP. Thrombocytosis. Blood. 2024, 143:1782. 10.1182\/blood.2023023702","journal-title":"Blood"},{"key":"ref24","article-title":"Scott-Brown\u2019s Otorhinolaryngology: Head and Neck Surgery, 8th Edition","author":"Watkinson JC","year":"2018","unstructured":"Watkinson JC, Clarke RW. Scott-Brown\u2019s Otorhinolaryngology: Head and Neck Surgery, 8th Edition. CRC Press, Boca Raton, FL; 2018."},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-021-02423-0","article-title":"To study the prevelance of extracranial & intracranial complications in chronic suppurative otitis media","volume":"74","author":"Verma P","year":"2022","unstructured":"Verma P, Gargava A, Saxena S, Narvey VP. To study the prevelance of extracranial &amp; intracranial complications in chronic suppurative otitis media. Indian J Otolaryngol Head Neck Surg. 2022, 74:608-11. 10.1007\/s12070-021-02423-0","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-010-0027-3","article-title":"A survey of ear, nose and throat disorders in rural India","volume":"62","author":"Singh A","year":"2010","unstructured":"Singh A, Kumar S. A survey of ear, nose and throat disorders in rural India. Indian J Otolaryngol Head Neck Surg. 2010, 62:121-4. 10.1007\/s12070-010-0027-3","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.medcli.2025.106915","article-title":"Chronic otitis media","volume":"164","author":"Larrosa F","year":"2025","unstructured":"Larrosa F, Pujol L, Hern\u00e1ndez-Montero E. Chronic otitis media. Med Clin (Barc). 2025, 164:106915. 10.1016\/j.medcli.2025.106915","journal-title":"Med Clin (Barc)"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.2015.1027133","article-title":"Chronic otitis media","volume":"127","author":"Wallis S","year":"2015","unstructured":"Wallis S, Atkinson H, Coatesworth AP. Chronic otitis media. Postgrad Med. 2015, 127:391-5. 10.1080\/00325481.2015.1027133","journal-title":"Postgrad Med"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.7432","article-title":"Status of lactate dehydrogenase, neutrophil-lymphocyte ratio, mean platelet volume, and platelet-lymphocyte ratio in Bell\u2019s palsy","volume":"12","author":"Baklac\u0131 D","year":"2020","unstructured":"Baklac\u0131 D, Guler \u0130, Kuzucu \u0130, Kum RO, \u00d6zcan M. Status of lactate dehydrogenase, neutrophil-lymphocyte ratio, mean platelet volume, and platelet-lymphocyte ratio in Bell\u2019s palsy. Cureus. 2020, 12:e7432. 10.7759\/cureus.7432","journal-title":"Cureus"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000003452","article-title":"The predictive value of neutrophil-lymphocyte and platelet-lymphocyte ratio for the effusion viscosity in otitis media with chronic effusion","volume":"28","author":"Elbistanli MS","year":"2017","unstructured":"Elbistanli MS, Ko\u00e7ak HE, Acipayam H, Yi\u011fider AP, Keskin M, Kayhan FT. The predictive value of neutrophil-lymphocyte and platelet-lymphocyte ratio for the effusion viscosity in otitis media with chronic effusion. J Craniofac Surg. 2017, 28:e244-7. 10.1097\/SCS.0000000000003452","journal-title":"J Craniofac Surg"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/981950","article-title":"The importance of the neutrophil-lymphocyte ratio in patients with idiopathic peripheral facial palsy","volume":"2015","author":"Kili\u00e7kaya MM","year":"2015","unstructured":"Kili\u00e7kaya MM, Tuz M, Yarikta\u015f M, Yasan H, Aynal\u0131 G, Bagci \u00d6. The importance of the neutrophil-lymphocyte ratio in patients with idiopathic peripheral facial palsy. Int J Otolaryngol. 2015, 2015:981950. 10.1155\/2015\/981950","journal-title":"Int J Otolaryngol"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-024-04985-1","article-title":"The predictive value of NLR, PLR and SII for SSNHL in children and young adults","volume":"76","author":"Liu Y","year":"2024","unstructured":"Liu Y, Ma G, Li Y, Wu Y. The predictive value of NLR, PLR and SII for SSNHL in children and young adults. Indian J Otolaryngol Head Neck Surg. 2024, 76:5393-9. 10.1007\/s12070-024-04985-1","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1016\/j.joto.2020.07.006","article-title":"Association between routine hematological parameters and sudden sensorineural hearing loss: a meta-analysis","volume":"16","author":"Ni W","year":"2021","unstructured":"Ni W, Song SP, Jiang YD. Association between routine hematological parameters and sudden sensorineural hearing loss: a meta-analysis. J Otol. 2021, 16:47-54. 10.1016\/j.joto.2020.07.006","journal-title":"J Otol"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002166","article-title":"Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as prognostic hematologic markers of Bell's palsy: a meta-analysis","volume":"40","author":"Oya R","year":"2019","unstructured":"Oya R, Takenaka Y, Imai T, Sato T, Oshima K, Ohta Y, Inohara H. Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as prognostic hematologic markers of Bell's palsy: a meta-analysis. Otol Neurotol. 2019, 40:681-7. 10.1097\/MAO.0000000000002166","journal-title":"Otol Neurotol"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.13805","article-title":"Neutrophil-lymphocyte and platelet-lymphocyte ratios in otitis media with effusion in children: diagnostic role and audiologic correlations","volume":"75","author":"Yukkald\u0131ran A","year":"2021","unstructured":"Yukkald\u0131ran A, Erdo\u011fan O, Kaplama ME. Neutrophil-lymphocyte and platelet-lymphocyte ratios in otitis media with effusion in children: diagnostic role and audiologic correlations. Int J Clin Pract. 2021, 75:e13805. 10.1111\/ijcp.13805","journal-title":"Int J Clin Pract"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.18388\/abp.2020_6028","article-title":"Investigation of EGF, IL1-\u03b1 and IL-6 levels and selected hematological parameters (NLR, MPV) in patients with the chronic cholesteatomatous otitis media","volume":"69","author":"\u00c7andar T","year":"2022","unstructured":"\u00c7andar T, Baklaci D, Bilgin E, Erdem D, Dalg\u0131\u00e7 M. Investigation of EGF, IL1-\u03b1 and IL-6 levels and selected hematological parameters (NLR, MPV) in patients with the chronic cholesteatomatous otitis media. Acta Biochim Pol. 2022, 69:633-7. 10.18388\/abp.2020_6028","journal-title":"Acta Biochim Pol"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-021-02898-x","article-title":"Correlation of the neutrophil-to-lymphocyte ratio with the middle ear risk index in patients with chronic otitis media","volume":"74","author":"\u0130\u015flek A","year":"2022","unstructured":"\u0130\u015flek A, Balc\u0131 MK, \u015eim\u015fek S. Correlation of the neutrophil-to-lymphocyte ratio with the middle ear risk index in patients with chronic otitis media. Indian J Otolaryngol Head Neck Surg. 2022, 74:4603-7. 10.1007\/s12070-021-02898-x","journal-title":"Indian J Otolaryngol Head Neck Surg"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000003484","article-title":"Can serum neutrophil-to-lymphocyte ratio be a predictive biomarker to help differentiate active chronic otitis media from inactive chronic otitis media?","volume":"28","author":"Tansuker HD","year":"2017","unstructured":"Tansuker HD, Ero\u011flu S, Yenig\u00fcn A, Ta\u015fkin \u00dc, Oktay MF. Can serum neutrophil-to-lymphocyte ratio be a predictive biomarker to help differentiate active chronic otitis media from inactive chronic otitis media?. J Craniofac Surg. 2017, 28:e260-3. 10.1097\/SCS.0000000000003484","journal-title":"J Craniofac Surg"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-021-02857-6","article-title":"A new biomarker in differentiation of mucosal chronic otitis media from squamous chronic otitis media: the systemic immune-inflammation index (SII)","volume":"74","author":"Y\u0131ld\u0131z E","year":"2022","unstructured":"Y\u0131ld\u0131z E, Kuzu S, G\u00fcnebakan \u00c7, Balc\u0131 A. A new biomarker in differentiation of mucosal chronic otitis media from squamous chronic otitis media: the systemic immune-inflammation index (SII). Indian J Otolaryngol Head Neck Surg. 2022, 74:476-82. 10.1007\/s12070-021-02857-6","journal-title":"Indian J Otolaryngol Head Neck Surg"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/426737-association-of-the-systemic-immune-inflammatory-index-neutrophil-to-lymphocyte-ratio-and-platelet-to-lymphocyte-ratio-in-the-differentiation-of-chronic-otitis-media-a-prospective-observational-analytical-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T06:59:02Z","timestamp":1762844342000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/426737-association-of-the-systemic-immune-inflammatory-index-neutrophil-to-lymphocyte-ratio-and-platelet-to-lymphocyte-ratio-in-the-differentiation-of-chronic-otitis-media-a-prospective-observational-analytical-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,10]]},"references-count":39,"URL":"https:\/\/doi.org\/10.7759\/cureus.96526","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11,10]]}}}