{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T09:26:40Z","timestamp":1762939600881,"version":"3.45.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,12]]},"DOI":"10.7759\/cureus.96646","type":"journal-article","created":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T09:23:43Z","timestamp":1762939423000},"source":"Crossref","is-referenced-by-count":0,"title":["Delayed Awakening Following General Anesthesia in a 74-Year-Old Female Patient: An Interplay of Physiological and Psychological Factors"],"prefix":"10.7759","author":[{"given":"Ba","family":"Lin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2021.07.021","article-title":"Anaesthetic depth and delirium after major surgery: a randomised clinical trial","volume":"127","author":"Evered LA","year":"2021","unstructured":"Evered LA, Chan MT, Han R, et al.. Anaesthetic depth and delirium after major surgery: a randomised clinical trial. Br J Anaesth. 2021, 127:704-12. 10.1016\/j.bja.2021.07.021","journal-title":"Br J Anaesth"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3182147f6d","article-title":"Review articles: postoperative delirium: acute change with long-term implications","volume":"112","author":"Rudolph JL","year":"2011","unstructured":"Rudolph JL, Marcantonio ER. Review articles: postoperative delirium: acute change with long-term implications. Anesth Analg. 2011, 112:1202-11. 10.1213\/ANE.0b013e3182147f6d","journal-title":"Anesth Analg"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199906000-00003","article-title":"The influence of age on propofol pharmacodynamics","volume":"90","author":"Schnider TW","year":"1999","unstructured":"Schnider TW, Minto CF, Shafer SL, Gambus PL, Andresen C, Goodale DB, Youngs EJ. The influence of age on propofol pharmacodynamics. Anesthesiology. 1999, 90:1502-16. 10.1097\/00000542-199906000-00003","journal-title":"Anesthesiology"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-2010-101086","article-title":"The impact of general and regional anesthesia on the incidence of post-operative cognitive dysfunction and post-operative delirium: a systematic review with meta-analysis","volume":"22 Suppl 3","author":"Mason SE","year":"2010","unstructured":"Mason SE, Noel-Storr A, Ritchie CW. The impact of general and regional anesthesia on the incidence of post-operative cognitive dysfunction and post-operative delirium: a systematic review with meta-analysis. J Alzheimers Dis. 2010, 22 Suppl 3:67-79. 10.3233\/JAD-2010-101086","journal-title":"J Alzheimers Dis"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2014.07.012","article-title":"Remote ischemic preconditioning prevents deterioration of short-term postoperative cognitive function after cardiac surgery using cardiopulmonary bypass: results of a pilot investigation","volume":"29","author":"Hudetz JA","year":"2015","unstructured":"Hudetz JA, Patterson KM, Iqbal Z, Gandhi SD, Pagel PS. Remote ischemic preconditioning prevents deterioration of short-term postoperative cognitive function after cardiac surgery using cardiopulmonary bypass: results of a pilot investigation. J Cardiothorac Vasc Anesth. 2015, 29:382-8. 10.1053\/j.jvca.2014.07.012","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2107138","article-title":"The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients","volume":"166","author":"Sessler CN","year":"2002","unstructured":"Sessler CN, Gosnell MS, Grap MJ, et al.. The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients. Am J Respir Crit Care Med. 2002, 166:1338-44. 10.1164\/rccm.2107138","journal-title":"Am J Respir Crit Care Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0000000000000395","article-title":"Residual neuromuscular blockade: management and impact on postoperative pulmonary outcome","volume":"29","author":"Fuchs-Buder T","year":"2016","unstructured":"Fuchs-Buder T, Nemes R, Schmartz D. Residual neuromuscular blockade: management and impact on postoperative pulmonary outcome. Curr Opin Anaesthesiol. 2016, 29:662-7. 10.1097\/ACO.0000000000000395","journal-title":"Curr Opin Anaesthesiol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(03)00252-5","article-title":"Preoperative prediction of severe postoperative pain","volume":"105","author":"Kalkman CJ","year":"2003","unstructured":"Kalkman CJ, Visser K, Moen J, et al.. Preoperative prediction of severe postoperative pain. Pain. 2003, 105:415-423. 10.1016\/S0304-3959(03)00252-5","journal-title":"Pain"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2014.10.019","article-title":"Postoperative delirium in older adults: best practice statement from the American Geriatrics Society","volume":"220","year":"2015","unstructured":"Postoperative delirium in older adults. best practice statement from the American Geriatrics Society. J Am Coll Surg. 2015, 220:136-48.e1. 10.1016\/j.jamcollsurg.2014.10.019","journal-title":"J Am Coll Surg"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1017\/cts.2025.6","article-title":"Preoperative anxiety and its impact on surgical outcomes: A systematic review and meta-analysis","volume":"9","author":"Shebl MA","year":"2025","unstructured":"Shebl MA, Toraih E, Shebl M, et al.. Preoperative anxiety and its impact on surgical outcomes: A systematic review and meta-analysis. J Clin Transl Sci. 2025, 9:e33. 10.1017\/cts.2025.6","journal-title":"J Clin Transl Sci"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1373\/jalm.2017.023150","article-title":"Pharmacogenetics of opioid use and implications for pain management","volume":"2","author":"Nerenz RD","year":"2018","unstructured":"Nerenz RD, Tsongalis GJ. Pharmacogenetics of opioid use and implications for pain management. J Appl Lab Med. 2018, 2:622-32. 10.1373\/jalm.2017.023150","journal-title":"J Appl Lab Med"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2024.02.006","article-title":"Neurobiological basis of emergence from anesthesia","volume":"47","author":"Song XJ","year":"2024","unstructured":"Song XJ, Hu JJ. Neurobiological basis of emergence from anesthesia. Trends Neurosci. 2024, 47:355-66. 10.1016\/j.tins.2024.02.006","journal-title":"Trends Neurosci"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aep291","article-title":"Postoperative delirium and cognitive dysfunction","volume":"103 Suppl 1","author":"Deiner S","year":"2009","unstructured":"Deiner S, Silverstein JH. Postoperative delirium and cognitive dysfunction. Br J Anaesth. 2009, 103 Suppl 1:i41-46. 10.1093\/bja\/aep291","journal-title":"Br J Anaesth"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.22005","article-title":"Effect of electroencephalography-guided anesthetic administration on Postoperative Delirium Among Older Adults undergoing major surgery: The ENGAGES randomized clinical trial","volume":"321","author":"Wildes TS","year":"2019","unstructured":"Wildes TS, Mickle AM, Ben Abdallah A, et al.. Effect of electroencephalography-guided anesthetic administration on Postoperative Delirium Among Older Adults undergoing major surgery: The ENGAGES randomized clinical trial. JAMA. 2019, 321:473-83. 10.1001\/jama.2018.22005","journal-title":"JAMA"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/430272-delayed-awakening-following-general-anesthesia-in-a-74-year-old-female-patient-an-interplay-of-physiological-and-psychological-factors","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T09:23:44Z","timestamp":1762939424000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/430272-delayed-awakening-following-general-anesthesia-in-a-74-year-old-female-patient-an-interplay-of-physiological-and-psychological-factors"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,12]]},"references-count":14,"URL":"https:\/\/doi.org\/10.7759\/cureus.96646","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11,12]]}}}