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N Engl J Med. 2005, 352:777-85. 10.1056\/NEJMoa042991","journal-title":"N Engl J Med"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.602888","article-title":"Does treatment of ruptured intracranial aneurysms within 24 hours improve clinical outcome?","volume":"42","author":"Phillips TJ","year":"2011","unstructured":"Phillips TJ, Dowling RJ, Yan B, Laidlaw JD, Mitchell PJ. Does treatment of ruptured intracranial aneurysms within 24 hours improve clinical outcome?. Stroke. 2011, 42:1936-45. 10.1161\/STROKEAHA.110.602888","journal-title":"Stroke"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1007\/s10143-013-0469-7","article-title":"Intraventricular fibrinolysis for severe aneurysmal intraventricular hemorrhage: a randomized controlled trial and meta-analysis","volume":"36","author":"Litrico S","year":"2013","unstructured":"Litrico S, Almairac F, Gaberel T, et al.. Intraventricular fibrinolysis for severe aneurysmal intraventricular hemorrhage: a randomized controlled trial and meta-analysis. Neurosurg Rev. 2013, 36:523-30. 10.1007\/s10143-013-0469-7","journal-title":"Neurosurg Rev"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)30195-3","article-title":"Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial","volume":"393","author":"Hanley DF","year":"2019","unstructured":"Hanley DF, Thompson RE, Rosenblum M, et al.. Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label, blinded endpoint phase 3 trial. Lancet. 2019, 393:1021-32. 10.1016\/S0140-6736(19)30195-3","journal-title":"Lancet"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.3171\/2023.3.JNS222567","article-title":"Early stellate ganglion block for improvement of postoperative cerebral blood flow velocity after aneurysmal subarachnoid hemorrhage: results of a pilot randomized controlled trial","volume":"139","author":"Wu Y","year":"2023","unstructured":"Wu Y, Lin F, Bai Y, et al.. Early stellate ganglion block for improvement of postoperative cerebral blood flow velocity after aneurysmal subarachnoid hemorrhage: results of a pilot randomized controlled trial. J Neurosurg. 2023, 139:1339-47. 10.3171\/2023.3.JNS222567","journal-title":"J Neurosurg"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2308440","article-title":"Trial of early minimally invasive removal of intracerebral hemorrhage","volume":"390","author":"Pradilla G","year":"2024","unstructured":"Pradilla G, Ratcliff JJ, Hall AJ, et al.. Trial of early minimally invasive removal of intracerebral hemorrhage. 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