{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T14:59:29Z","timestamp":1763477969379,"version":"3.45.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,18]]},"DOI":"10.7759\/cureus.97156","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T14:55:42Z","timestamp":1763477742000},"source":"Crossref","is-referenced-by-count":0,"title":["A Fatal Case of Adenovirus Encephalitis in an Adult With End-Stage Renal Disease"],"prefix":"10.7759","author":[{"given":"Xiong Khee","family":"Cheong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juen Kiem","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ummu Afeera","family":"Zainulabid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Najma","family":"Kori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petrick Ramesh","family":"Periyasamy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1309\/AWXD-GNC5-D70E-N7YT","article-title":"Fatal disseminated adenovirus infections in immunocompromised patients","volume":"120","author":"Pham TT","year":"2003","unstructured":"Pham TT, Burchette JL Jr, Hale LP. Fatal disseminated adenovirus infections in immunocompromised patients. Am J Clin Pathol. 2003, 120:575-83. 10.1309\/AWXD-GNC5-D70E-N7YT","journal-title":"Am J Clin Pathol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(74)91639-0","article-title":"Assessment of coma and impaired consciousness. A practical scale","volume":"2","author":"Teasdale G","year":"1974","unstructured":"Teasdale G, Jennett B. Assessment of coma and impaired consciousness. A practical scale. Lancet. 1974, 2:81-4. 10.1016\/s0140-6736(74)91639-0","journal-title":"Lancet"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182904f96","article-title":"Fatal adenovirus encephalomyeloradiculitis in an umbilical cord stem cell transplant recipient","volume":"80","author":"Awosika OO","year":"2013","unstructured":"Awosika OO, Lyons JL, Ciarlini P, et al.. Fatal adenovirus encephalomyeloradiculitis in an umbilical cord stem cell transplant recipient. Neurology. 2013, 80:1715-17. 10.1212\/WNL.0b013e3182904f96","journal-title":"Neurology"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00080-11","article-title":"Adenoviral infection presenting as an isolated central nervous system disease without detectable viremia in two children after stem cell transplantation","volume":"49","author":"Frange P","year":"2011","unstructured":"Frange P, Peffault de Latour R, Arnaud C, et al.. Adenoviral infection presenting as an isolated central nervous system disease without detectable viremia in two children after stem cell transplantation. J Clin Microbiol. 2011, 49:2361-4. 10.1128\/JCM.00080-11","journal-title":"J Clin Microbiol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890470210","article-title":"Adenovirus mixture isolated from the brain of an AIDS patient with encephalitis","volume":"47","author":"Schnurr D","year":"1995","unstructured":"Schnurr D, Bollen A, Crawford-Miksza L, Dondero ME, Yagi S. Adenovirus mixture isolated from the brain of an AIDS patient with encephalitis. J Med Virol. 1995, 47:168-71. 10.1002\/jmv.1890470210","journal-title":"J Med Virol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2017.08.004","article-title":"Disseminated adenovirus nephritis after kidney transplantation","volume":"3","author":"Hatlen T","year":"2018","unstructured":"Hatlen T, Mroch H, Tuttle K, Ojogho O, Rooney M, Desmond S, Bani-Hani S. Disseminated adenovirus nephritis after kidney transplantation. Kidney Int Rep. 2018, 3:19-23. 10.1016\/j.ekir.2017.08.004","journal-title":"Kidney Int Rep"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2004.10.090","article-title":"Hemorrhagic adenovirus cystitis after renal transplantation","volume":"36","author":"Hofland CA","year":"2004","unstructured":"Hofland CA, Eron LJ, Washecka RM. Hemorrhagic adenovirus cystitis after renal transplantation. Transplant Proc. 2004, 36:3025-7. 10.1016\/j.transproceed.2004.10.090","journal-title":"Transplant Proc"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.05629-11","article-title":"Real-time qualitative PCR for 57 human adenovirus types from multiple specimen sources","volume":"50","author":"Buckwalter SP","year":"2012","unstructured":"Buckwalter SP, Teo R, Espy MJ, Sloan LM, Smith TF, Pritt BS. Real-time qualitative PCR for 57 human adenovirus types from multiple specimen sources. J Clin Microbiol. 2012, 50:766-71. 10.1128\/JCM.05629-11","journal-title":"J Clin Microbiol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4103\/jnrp.jnrp_120_18","article-title":"Magnetic resonance imaging findings in viral encephalitis: a pictorial essay","volume":"9","author":"Jayaraman K","year":"2018","unstructured":"Jayaraman K, Rangasami R, Chandrasekharan A. Magnetic resonance imaging findings in viral encephalitis: a pictorial essay. J Neurosci Rural Pract. 2018, 9:556-60. 10.4103\/jnrp.jnrp_120_18","journal-title":"J Neurosci Rural Pract"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-016-2370-2","article-title":"Severe community-acquired adenovirus pneumonia treated with oral ribavirin: a case report","volume":"10","author":"Yoon BW","year":"2017","unstructured":"Yoon BW, Song YG, Lee SH. Severe community-acquired adenovirus pneumonia treated with oral ribavirin: a case report. BMC Res Notes. 2017, 10:47. 10.1186\/s13104-016-2370-2","journal-title":"BMC Res Notes"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmcr.2020.101037","article-title":"Severe community acquired adenovirus pneumonia in an immunocompetent host successfully treated with IV cidofovir","volume":"30","author":"Zhao J","year":"2020","unstructured":"Zhao J, Yap A, Wu E, Low CY, Yap J. Severe community acquired adenovirus pneumonia in an immunocompetent host successfully treated with IV cidofovir. Respir Med Case Rep. 2020, 30:101037. 10.1016\/j.rmcr.2020.101037","journal-title":"Respir Med Case Rep"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/s0163-4453(98)80021-2","article-title":"Failure of intravenous ribavirin in the treatment of invasive adenovirus infection following allogeneic bone marrow transplantation: a case report","volume":"36","author":"Mann D","year":"1998","unstructured":"Mann D, Moreb J, Smith S, Gian V. Failure of intravenous ribavirin in the treatment of invasive adenovirus infection following allogeneic bone marrow transplantation: a case report. J Infection. 1998, 36:227-8. 10.1016\/s0163-4453(98)80021-2","journal-title":"J Infection"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/phar.2194","article-title":"Adjunctive use of cidofovir and intravenous immunoglobulin to treat invasive adenoviral disease in solid organ transplant recipients","volume":"38","author":"Permpalung N","year":"2018","unstructured":"Permpalung N, Mahoney MV, Alonso CD. Adjunctive use of cidofovir and intravenous immunoglobulin to treat invasive adenoviral disease in solid organ transplant recipients. Pharmacotherapy. 2018, 38:1260-6. 10.1002\/phar.2194","journal-title":"Pharmacotherapy"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01343-13","article-title":"Single-dose pharmacokinetics of cidofovir in continuous venovenous hemofiltration","volume":"58","author":"Vossen MG","year":"2014","unstructured":"Vossen MG, Gattringer KB, J\u00e4ger W, Kraff S, Thalhammer F. Single-dose pharmacokinetics of cidofovir in continuous venovenous hemofiltration. Antimicrob Agents Chemother. 2014, 58:1952-5. 10.1128\/AAC.01343-13","journal-title":"Antimicrob Agents Chemother"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(22)00199-6","article-title":"Use of cidofovir in recent outbreak of adenovirus-associated acute liver failure in children","volume":"7","author":"Verma A","year":"2022","unstructured":"Verma A, Vimalesvaran S, Lampejo T, Deep A, Dhawan A. Use of cidofovir in recent outbreak of adenovirus-associated acute liver failure in children. Lancet Gastroenterol Hepatol. 2022, 7:700-2. 10.1016\/S2468-1253(22)00199-6","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9236(99)70118-9","article-title":"Pharmacokinetics of cidofovir in renal insufficiency and in continuous ambulatory peritoneal dialysis or high-flux hemodialysis","volume":"65","author":"Brody SR","year":"1999","unstructured":"Brody SR, Humphreys MH, Gambertoglio JG, Schoenfeld P, Cundy KC, Aweeka FT. Pharmacokinetics of cidofovir in renal insufficiency and in continuous ambulatory peritoneal dialysis or high-flux hemodialysis. Clin Pharmacol Ther. 1999, 65:21-8. 10.1016\/S0009-9236(99)70118-9","journal-title":"Clin Pharmacol Ther"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.5296","article-title":"Brincidofovir (CMX001) for the treatment of severe adenoviral pneumonia in kidney transplant recipient","volume":"11","author":"Sudhindra P","year":"2019","unstructured":"Sudhindra P, Knoll B, Nog R, Singh N, Dhand A. Brincidofovir (CMX001) for the treatment of severe adenoviral pneumonia in kidney transplant recipient. Cureus. 2019, 11:10.7759\/cureus.5296","journal-title":"Cureus"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2017.09.013","article-title":"Disseminated adenovirus infection after allogeneic stem cell transplant and the potential role of brincidofovir - case series and 10 year experience of management in an adult transplant cohort","volume":"96","author":"Ramsay ID","year":"2017","unstructured":"Ramsay ID, Attwood C, Irish D, Griffiths PD, Kyriakou C, Lowe DM. Disseminated adenovirus infection after allogeneic stem cell transplant and the potential role of brincidofovir - case series and 10 year experience of management in an adult transplant cohort. J Clin Virol. 2017, 96:73-9. 10.1016\/j.jcv.2017.09.013","journal-title":"J Clin Virol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/429385-a-fatal-case-of-adenovirus-encephalitis-in-an-adult-with-end-stage-renal-disease","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T14:55:42Z","timestamp":1763477742000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/429385-a-fatal-case-of-adenovirus-encephalitis-in-an-adult-with-end-stage-renal-disease"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,18]]},"references-count":18,"URL":"https:\/\/doi.org\/10.7759\/cureus.97156","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11,18]]}}}