{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,23]],"date-time":"2025-11-23T08:26:26Z","timestamp":1763886386990,"version":"3.45.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,23]]},"DOI":"10.7759\/cureus.97533","type":"journal-article","created":{"date-parts":[[2025,11,23]],"date-time":"2025-11-23T08:25:52Z","timestamp":1763886352000},"source":"Crossref","is-referenced-by-count":0,"title":["Peutz-Jeghers Syndrome With Malignant Transformation in a Hamartomatous Rectal Polyp: A Case Report"],"prefix":"10.7759","author":[{"given":"Omar","family":"Bahlaoui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anass","family":"Nadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Afafe","family":"Taiymi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wafaa","family":"Khannoussi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imane","family":"Ben El Brhdadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1684\/bdc.2014.1942","article-title":"[Hereditary predisposition to cancers of the digestive tract, breast, gynecological and gonadal: focus on the Peutz-Jeghers]","volume":"101","author":"Turpin A","year":"2014","unstructured":"Turpin A, Cattan S, Leclerc J, Wacrenier A, Manouvrier-Hanu S, Buisine MP, Lejeune-Dumoulin S. [Hereditary predisposition to cancers of the digestive tract, breast, gynecological and gonadal: focus on the Peutz-Jeghers]. Bull Cancer. 2014, 101:813-22. 10.1684\/bdc.2014.1942","journal-title":"Bull Cancer"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.5177\/ntvt.2013.01.12215","article-title":"[Peutz-Jeghers syndrome]","volume":"120","author":"Korsse SE","year":"2013","unstructured":"Korsse SE, van Leerdam ME, Dekker E. [Peutz-Jeghers syndrome]. Ned Tijdschr Tandheelkd. 2013, 120:12-6. 10.5177\/ntvt.2013.01.12215","journal-title":"Ned Tijdschr Tandheelkd"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM194912222412501","article-title":"Generalized intestinal polyposis and melanin spots of the oral mucosa, lips and digits\u2014a syndrome of diagnostic significance","volume":"241","author":"Jeghers H","year":"1949","unstructured":"Jeghers H, McKusick VA, Katz KH. Generalized intestinal polyposis and melanin spots of the oral mucosa, lips and digits\u2014a syndrome of diagnostic significance. N Engl J Med. 1949, 241:993-1005. 10.1056\/NEJM194912222412501","journal-title":"N Engl J Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2009.198499","article-title":"Peutz-Jeghers syndrome: a systematic review and recommendations for management","volume":"59","author":"Beggs AD","year":"2010","unstructured":"Beggs AD, Latchford AR, Vasen HF, et al.. Peutz-Jeghers syndrome: a systematic review and recommendations for management. Gut. 2010, 59:975-86. 10.1136\/gut.2009.198499","journal-title":"Gut"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000002248","article-title":"Management of Peutz-Jeghers syndrome in children and adolescents: a position paper from the ESPGHAN polyposis working group","volume":"68","author":"Latchford A","year":"2019","unstructured":"Latchford A, Cohen S, Auth M, et al.. Management of Peutz-Jeghers syndrome in children and adolescents: a position paper from the ESPGHAN polyposis working group. J Pediatr Gastroenterol Nutr. 2019, 68:442-52. 10.1097\/MPG.0000000000002248","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1055\/a-0965-0605","article-title":"Endoscopic management of polyposis syndromes: European Society of Gastrointestinal Endoscopy (ESGE) guideline","volume":"51","author":"van Leerdam ME","year":"2019","unstructured":"van Leerdam ME, Roos VH, van Hooft JE, et al.. Endoscopic management of polyposis syndromes: European Society of Gastrointestinal Endoscopy (ESGE) guideline. Endoscopy. 2019, 51:877-95. 10.1055\/a-0965-0605","journal-title":"Endoscopy"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-06-0083","article-title":"Frequency and spectrum of cancers in the Peutz-Jeghers syndrome","volume":"12","author":"Hearle N","year":"2006","unstructured":"Hearle N, Schumacher V, Menko FH, et al.. Frequency and spectrum of cancers in the Peutz-Jeghers syndrome. Clin Cancer Res. 2006, 12:3209-15. 10.1158\/1078-0432.CCR-06-0083","journal-title":"Clin Cancer Res"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1177\/1010428317705131","article-title":"Cancer risk in patients with Peutz-Jeghers syndrome: a retrospective cohort study of 336 cases","volume":"39","author":"Chen HY","year":"2017","unstructured":"Chen HY, Jin XW, Li BR, et al.. Cancer risk in patients with Peutz-Jeghers syndrome: a retrospective cohort study of 336 cases. Tumour Biol. 2017, 39:1010428317705131. 10.1177\/1010428317705131","journal-title":"Tumour Biol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-015-1296-y","article-title":"Update on our investigation of malignant tumors associated with Peutz-Jeghers syndrome in Japan","volume":"46","author":"Ishida H","year":"2016","unstructured":"Ishida H, Tajima Y, Gonda T, Kumamoto K, Ishibashi K, Iwama T. Update on our investigation of malignant tumors associated with Peutz-Jeghers syndrome in Japan. Surg Today. 2016, 46:1231-42. 10.1007\/s00595-015-1296-y","journal-title":"Surg Today"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.gcb.2008.01.009","article-title":"[Peutz-Jeghers' syndrome with malignant development in a hamartomatous polyp: report of one case and review of the literature]","volume":"32","author":"Bouraoui S","year":"2008","unstructured":"Bouraoui S, Azouz H, Kechrid H, Lemaiem F, Mzabi-Regaya S. [Peutz-Jeghers' syndrome with malignant development in a hamartomatous polyp: report of one case and review of the literature]. Gastroenterol Clin Biol. 2008, 32:250-4. 10.1016\/j.gcb.2008.01.009","journal-title":"Gastroenterol Clin Biol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.15761\/GHE.1000104","article-title":"Hamartoma-adenoma-carcinoma sequence in a solitary Peutz-Jeghers-type sigmoid polyp","volume":"1","author":"Altonbary AY","year":"2016","unstructured":"Altonbary AY, Bahgat MH, Elkashef WF. Hamartoma-adenoma-carcinoma sequence in a solitary Peutz-Jeghers-type sigmoid polyp. Gastroenterol Hepatol Endosc. 2016, 1:18. 10.15761\/GHE.1000104","journal-title":"Gastroenterol Hepatol Endosc"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/436194-peutz-jeghers-syndrome-with-malignant-transformation-in-a-hamartomatous-rectal-polyp-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,23]],"date-time":"2025-11-23T08:25:53Z","timestamp":1763886353000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/436194-peutz-jeghers-syndrome-with-malignant-transformation-in-a-hamartomatous-rectal-polyp-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,23]]},"references-count":11,"URL":"https:\/\/doi.org\/10.7759\/cureus.97533","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11,23]]}}}