{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T07:34:02Z","timestamp":1768030442258,"version":"3.49.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,26]]},"DOI":"10.7759\/cureus.97853","type":"journal-article","created":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T14:00:15Z","timestamp":1764165615000},"source":"Crossref","is-referenced-by-count":1,"title":["Bifascicular Block Associated With Myocardial Infarction: A Marker of Proximal Left Anterior Descending Artery Occlusion Confirmed by the Artificial Intelligence-Based Smartphone App Queen of Hearts"],"prefix":"10.7759","author":[{"given":"Lucio Giuseppe","family":"Granata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Russo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simona","family":"Giubilato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marilena","family":"Scarabelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Amico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehad191","article-title":"2023 ESC Guidelines for the management of acute coronary syndromes","volume":"44","author":"Byrne RA","year":"2023","unstructured":"Byrne RA, Rossello X, Coughlan JJ, et al.. 2023 ESC Guidelines for the management of acute coronary syndromes. Eur Heart J. 2023, 44:3720-826. 10.1093\/eurheartj\/ehad191","journal-title":"Eur Heart J"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacadv.2024.101314","article-title":"From ST-segment elevation MI to occlusion MI: the new paradigm shift in acute myocardial infarction","volume":"3","author":"McLaren J","year":"2024","unstructured":"McLaren J, de Alencar JN, Aslanger EK, Meyers HP, Smith SW. From ST-segment elevation MI to occlusion MI: the new paradigm shift in acute myocardial infarction. JACC Adv. 2024, 3:101314. 10.1016\/j.jacadv.2024.101314","journal-title":"JACC Adv"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1177\/2048872618809700","article-title":"Right bundle branch block in patients with suspected myocardial infarction","volume":"8","author":"Neumann JT","year":"2019","unstructured":"Neumann JT, S\u00f6rensen NA, R\u00fcbsamen N, et al.. Right bundle branch block in patients with suspected myocardial infarction. Eur Heart J Acute Cardiovasc Care. 2019, 8:161-6. 10.1177\/2048872618809700","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-018-0430-3","article-title":"Bundle branch blocks and\/or hemiblocks complicating acute myocardial ischemia or infarction","volume":"52","author":"L\u00e9vy S","year":"2018","unstructured":"L\u00e9vy S. Bundle branch blocks and\/or hemiblocks complicating acute myocardial ischemia or infarction. J Interv Card Electrophysiol. 2018, 52:287-92. 10.1007\/s10840-018-0430-3","journal-title":"J Interv Card Electrophysiol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2024.11.019","article-title":"ECG patterns of occlusion myocardial infarction: a narrative review","volume":"85","author":"Ricci F","year":"2025","unstructured":"Ricci F, Martini C, Scordo DM, et al.. ECG patterns of occlusion myocardial infarction: a narrative review. Ann Emerg Med. 2025, 85:330-40. 10.1016\/j.annemergmed.2024.11.019","journal-title":"Ann Emerg Med"},{"key":"ref6","unstructured":"Powerful Medical. Research. PMcardio. AI-powered ECG interpretation. (2025). Accessed: October 30, 2025: http:\/\/\/\/www.powerfulmedical.com\/research\/?utm_source=pmcardio_individuals&amp;utm_medium=website&amp;utm_campaign=impact_sec...."},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs291","article-title":"Right bundle branch block: prevalence, risk factors, and outcome in the general population: results from the Copenhagen City Heart Study","volume":"34","author":"Bussink BE","year":"2013","unstructured":"Bussink BE, Holst AG, Jespersen L, Deckers JW, Jensen GB, Prescott E. Right bundle branch block: prevalence, risk factors, and outcome in the general population: results from the Copenhagen City Heart Study. Eur Heart J. 2013, 34:138-46. 10.1093\/eurheartj\/ehs291","journal-title":"Eur Heart J"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx393","article-title":"2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC)","volume":"39","author":"Ibanez B","year":"2018","unstructured":"Ibanez B, James S, Agewall S, et al.. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J. 2018, 39:119-77. 10.1093\/eurheartj\/ehx393","journal-title":"Eur Heart J"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr291","article-title":"Primary angioplasty in acute myocardial infarction with right bundle branch block: should new onset right bundle branch block be added to future guidelines as an indication for reperfusion therapy?","volume":"33","author":"Widimsky P","year":"2012","unstructured":"Widimsky P, Roh\u00e1c F, St\u00e1sek J, et al.. Primary angioplasty in acute myocardial infarction with right bundle branch block: should new onset right bundle branch block be added to future guidelines as an indication for reperfusion therapy?. Eur Heart J. 2012, 33:86-95. 10.1093\/eurheartj\/ehr291","journal-title":"Eur Heart J"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2006.02.010","article-title":"Right bundle-branch block in anterior acute myocardial infarction in the coronary intervention era: acute angiographic findings and prognosis","volume":"116","author":"Kurisu S","year":"2007","unstructured":"Kurisu S, Inoue I, Kawagoe T, et al.. Right bundle-branch block in anterior acute myocardial infarction in the coronary intervention era: acute angiographic findings and prognosis. Int J Cardiol. 2007, 116:57-61. 10.1016\/j.ijcard.2006.02.010","journal-title":"Int J Cardiol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.04.060","article-title":"Right, but not left, bundle branch block is associated with large anteroseptal scar","volume":"62","author":"Strauss DG","year":"2013","unstructured":"Strauss DG, Loring Z, Selvester RH, et al.. Right, but not left, bundle branch block is associated with large anteroseptal scar. J Am Coll Cardiol. 2013, 62:959-67. 10.1016\/j.jacc.2013.04.060","journal-title":"J Am Coll Cardiol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpcardiol.2022.101418","article-title":"Right bundle branch and bifascicular blocks: insensitive prognostic indicators for acute myocardial infarction","volume":"48","author":"Rector G","year":"2023","unstructured":"Rector G, Triska J, Ajene G, et al.. Right bundle branch and bifascicular blocks: insensitive prognostic indicators for acute myocardial infarction. Curr Probl Cardiol. 2023, 48:101418. 10.1016\/j.cpcardiol.2022.101418","journal-title":"Curr Probl Cardiol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2008.09.039","article-title":"Right bundle-branch block in acute coronary syndrome: diagnostic and therapeutic implications for the emergency physician","volume":"27","author":"Horton CL","year":"2009","unstructured":"Horton CL, Brady WJ. Right bundle-branch block in acute coronary syndrome: diagnostic and therapeutic implications for the emergency physician. Am J Emerg Med. 2009, 27:1130-41. 10.1016\/j.ajem.2008.09.039","journal-title":"Am J Emerg Med"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/ehjacc\/zuab026","article-title":"Association between new-onset right bundle branch block and primary or secondary ventricular fibrillation in ST-segment elevation myocardial infarction","volume":"10","author":"Galcer\u00e1-Jornet E","year":"2021","unstructured":"Galcer\u00e1-Jornet E, Consuegra-S\u00e1nchez L, Galcer\u00e1-Tom\u00e1s J, et al.. Association between new-onset right bundle branch block and primary or secondary ventricular fibrillation in ST-segment elevation myocardial infarction. Eur Heart J Acute Cardiovasc Care. 2021, 10:918-25. 10.1093\/ehjacc\/zuab026","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.86103","article-title":"New right bundle branch block: a benign variant or an ominous sign?","volume":"17","author":"Myint Thu T","year":"2025","unstructured":"Myint Thu T, Hegazy A, Dancy L. New right bundle branch block: a benign variant or an ominous sign?. Cureus. 2025, 17:e86103. 10.7759\/cureus.86103","journal-title":"Cureus"},{"key":"ref16","unstructured":"Emergency Medicine Cases. McLaren J. ECG Cases 12. RBBB and occlusion MI. (2020). Accessed: October 30, 2025: https:\/\/emergencymedicinecases.com\/ecg-rbbb-occlusion-mi\/."},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2025.07.061","article-title":"Accuracy of cath lab activation decisions for STEMI-equivalent and mimic ECGs: physicians vs. AI (Queen of Hearts by PMcardio)","volume":"97","author":"Shroyer S","year":"2025","unstructured":"Shroyer S, Mehta S, Thukral N, Smiley K, Mercaldo N, Meyers HP, Smith SW. Accuracy of cath lab activation decisions for STEMI-equivalent and mimic ECGs: physicians vs. AI (Queen of Hearts by PMcardio). Am J Emerg Med. 2025, 97:193-9. 10.1016\/j.ajem.2025.07.061","journal-title":"Am J Emerg Med"},{"key":"ref18","doi-asserted-by":"crossref","DOI":"10.1161\/circ.150.suppl_1.4141318","article-title":"AI-powered smartphone application for detection of left ventricular systolic dysfunction using 12-lead ECG","volume":"150","author":"Demolder A","year":"2024","unstructured":"Demolder A, Herman R, Vavrik B, et al.. AI-powered smartphone application for detection of left ventricular systolic dysfunction using 12-lead ECG. Circulation. 2024, 150:4141318.","journal-title":"Circulation"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2025.10.018","article-title":"AI-enabled ECG analysis improves diagnostic accuracy and reduces false STEMI activations: a multicenter U.S. registry [in press]","author":"Herman R","year":"2025","unstructured":"Herman R, Mumma BE, Hoyne JD, et al.. AI-enabled ECG analysis improves diagnostic accuracy and reduces false STEMI activations: a multicenter U.S. registry [in press]. JACC Cardiovasc Interv. 2025, 10.1016\/j.jcin.2025.10.018","journal-title":"JACC Cardiovasc Interv"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacadv.2025.102227","article-title":"A diagnostic paradigm shift in acute myocardial infarction: rationale and design of the DIFOCCULT-3 trial","author":"Aslanger EK","year":"2025","unstructured":"Aslanger EK, Agg\u00fcl B, Y\u0131ld\u0131r\u0131mt\u00fcrk \u00d6, Karabay CY, Meyers HP, Smith SW, De\u011fertekin M. A diagnostic paradigm shift in acute myocardial infarction: rationale and design of the DIFOCCULT-3 trial. JACC Adv. 2025, 102227. 10.1016\/j.jacadv.2025.102227","journal-title":"JACC Adv"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/436762-bifascicular-block-associated-with-myocardial-infarction-a-marker-of-proximal-left-anterior-descending-artery-occlusion-confirmed-by-the-artificial-intelligence-based-smartphone-app-queen-of-hearts","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T14:00:18Z","timestamp":1764165618000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/436762-bifascicular-block-associated-with-myocardial-infarction-a-marker-of-proximal-left-anterior-descending-artery-occlusion-confirmed-by-the-artificial-intelligence-based-smartphone-app-queen-of-hearts"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,26]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.97853","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11,26]]}}}