{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T12:46:30Z","timestamp":1785329190402,"version":"3.55.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,8,17]]},"DOI":"10.7759\/cureus.9815","type":"journal-article","created":{"date-parts":[[2020,8,17]],"date-time":"2020-08-17T18:46:17Z","timestamp":1597689977000},"source":"Crossref","is-referenced-by-count":2,"title":["Splenic Infarct Secondary to High Altitude Exposure in Sickle Cell Trait Patients: A Case Series"],"prefix":"10.7759","author":[{"given":"Luis","family":"Gonzalez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andres F","family":"Shapiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Tafur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Plaza-Meneses","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brenner","family":"Sabando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","article-title":"Splenic syndrome in patients at high altitude with unrecognized sickle cell trait: splenectomy is often unnecessary","volume":"48","author":"Sheikha A","year":"2005","unstructured":"Sheikha A. Splenic syndrome in patients at high altitude with unrecognized sickle cell trait: splenectomy is often unnecessary. Can J Surg. 2005, 48:377-381.","journal-title":"Can J Surg"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2010.1.418","article-title":"Sickle-cell trait: novel clinical significance","volume":"2010","author":"Key NS","year":"2010","unstructured":"Key NS, Derebail VK. Sickle-cell trait: novel clinical significance. Hematology Am Soc Hematol Educ Program. 2010, 2010:418-422. 10.1182\/asheducation-2010.1.418","journal-title":"Hematology Am Soc Hematol Educ Program"},{"key":"ref3","article-title":"Incidence of sickle cell trait-United States, 2010","volume":"63","author":"Ojodu J","year":"2014","unstructured":"Ojodu J, Hulihan MM, Pope SN, Grant AM. Incidence of sickle cell trait-United States, 2010. MMWR Morb Mortal Wkly Rep. 2014, 63:1155-1158.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.12.020","article-title":"Complications associated with sickle cell trait: a brief narrative review","volume":"122","author":"Tsaras G","year":"2009","unstructured":"Tsaras G, Owusu-Ansah A, Boateng FO, Amoateng-Adjepong Y. Complications associated with sickle cell trait: a brief narrative review. Am J Med. 2009, 122:507-512. 10.1016\/j.amjmed.2008.12.020","journal-title":"Am J Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2016.08.023","article-title":"How benign is sickle cell trait?","volume":"11","author":"Gibson JS","year":"2016","unstructured":"Gibson JS, Rees DC. How benign is sickle cell trait?. EBioMedicine. 2016, 11:21-22. 10.1016\/j.ebiom.2016.08.023","journal-title":"EBioMedicine"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2013.05.009","article-title":"Acute splenic syndrome in an African-American male with sickle cell trait on a commercial airplane flight","volume":"45","author":"Murano T","year":"2013","unstructured":"Murano T, Fox AD, Anjaria D. Acute splenic syndrome in an African-American male with sickle cell trait on a commercial airplane flight. J Emerg Med. 2013, 45:161-165. 10.1016\/j.jemermed.2013.05.009","journal-title":"J Emerg Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1089\/ham.2014.1034","article-title":"The splenic syndrome in individuals with sickle cell trait","volume":"15","author":"Goodman J","year":"2014","unstructured":"Goodman J, Hassell K, Irwin D, Witkowski EH, Nuss R. The splenic syndrome in individuals with sickle cell trait. High Alt Med Biol. 2014, 15:468-471. 10.1089\/ham.2014.1034","journal-title":"High Alt Med Biol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.5505\/1304.7361.2015.16769","article-title":"A rare cause of acute abdominal pain: Splenic infarct (case series)","volume":"15","author":"Ozakin E","year":"2015","unstructured":"Ozakin E, Cetinkaya O, Baloglu Kaya F, Acar N, Cevik AA. A rare cause of acute abdominal pain: Splenic infarct (case series). urk J Emerg Med. 2015, 15:96-99. 10.5505\/1304.7361.2015.16769","journal-title":"urk J Emerg Med"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2008.02.014","article-title":"Splenic infarction: 10 years of experience","volume":"27","author":"Antopolsky M","year":"2009","unstructured":"Antopolsky M, Hiller N, Salameh S, Goldshtein B,\r\nStalnikowicz R. Splenic infarction: 10 years of experience. Am J Emerg Med. 2009, 27:262-265. 10.1016\/j.ajem.2008.02.014","journal-title":"Am J Emerg Med"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000001363","article-title":"Acute splenic infarction at an academic general hospital over 10 years: presentation, etiology, and outcome","volume":"94","author":"Schattner A","year":"2015","unstructured":"Schattner A, Adi M, Kitroser E, Klepfish A. Acute splenic infarction at an academic general hospital over 10 years: presentation, etiology, and outcome. Medicine (Baltimore). 2015, 94:1363. 10.1097\/MD.0000000000001363","journal-title":"Medicine (Baltimore)"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/trstmh\/tru095","article-title":"Splenic infarction and malaria","volume":"108","author":"Norman FF","year":"2014","unstructured":"Norman FF, Rojas-Marcos J, Hermida-Donate JM, Monge-Maillo B, Perez-Molina JA, L\u00f3pez-V\u00e9lez R. Splenic infarction and malaria. Trans R Soc Trop Med Hyg. 2014, 108:455-460. 10.1093\/trstmh\/tru095","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1053\/j.sult.2006.06.004","article-title":"Multiple lesions of the spleen: differential diagnosis of cystic and solid lesions","volume":"27","author":"Kamaya A","year":"2006","unstructured":"Kamaya A, Weinstein S, Desser TS. Multiple lesions of the spleen: differential diagnosis of cystic and solid lesions. Semin Ultrasound CT MR. 2006, 27:389-403. 10.1053\/j.sult.2006.06.004","journal-title":"Semin Ultrasound CT MR"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1985.03350390093033","article-title":"Splenic syndrome at mountain altitudes in sickle cell trait: its occurrence in nonblack persons","volume":"253","author":"Lane PA","year":"1985","unstructured":"Lane PA, Githens JH. Splenic syndrome at mountain altitudes in sickle cell trait: its occurrence in nonblack persons. JAMA. 1985, 253:2251-2254. 10.1001\/jama.1985.03350390093033","journal-title":"JAMA"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-199004000-00033","article-title":"Survival of patients with sickle cell anemia living at high altitude","volume":"83","author":"Addae S","year":"1990","unstructured":"Addae S, Adzaku F, Mohammed S, Annobil S. Survival of patients with sickle cell anemia living at high altitude. South Med J. 1990, 83:487. 10.1097\/00007611-199004000-00033","journal-title":"South Med J"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.4103\/ijabmr.ijabmr_369_16","article-title":"Splenic infarction in two members of the family with sickle cell trait: a case report of rare complication","volume":"7","author":"Sinha MK","year":"2017","unstructured":"Sinha MK, Raghuwanshi B, Bag ND, Barman A. Splenic infarction in two members of the family with sickle cell trait: a case report of rare complication. Int J Appl Basic Med Res. 2017, 7:272-274. 10.4103\/ijabmr.ijabmr_369_16","journal-title":"Int J Appl Basic Med Res"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S0377-1237(08)80052-4","article-title":"Splenic syndrome due to sickle cell trait amongst Indian soldiers serving in Kashmir","volume":"64","author":"Arora MM","year":"2008","unstructured":"Arora MM, Bhatia JK, Khanna V, Jaiswal P, Charan VD. Splenic syndrome due to sickle cell trait amongst Indian soldiers serving in Kashmir. Med J Armed Forces India. 2008, 64:123-126. 10.1016\/S0377-1237(08)80052-4","journal-title":"Med J Armed Forces India"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2012.05.033","article-title":"Splenic infarction at high altitude secondary to sickle cell trait","volume":"31","author":"Scordino D","year":"2013","unstructured":"Scordino D, Kirsch T. Splenic infarction at high altitude secondary to sickle cell trait. Am J Emerg Med. 2013, 31:446.E1-446.E3. 10.1016\/j.ajem.2012.05.033","journal-title":"Am J Emerg Med"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.7205\/MILMED.173.12.1233","article-title":"Splenic syndrome: a rare indication for splenectomy","volume":"173","author":"Pothula V","year":"2008","unstructured":"Pothula V, Saegusa E, Takekoshi D, Edson T, Ignacio R. Splenic syndrome: a rare indication for splenectomy. Mil Med. 2008, 173:1233-1237. 10.7205\/MILMED.173.12.1233","journal-title":"Mil Med"},{"key":"ref19","article-title":"Infarto Espl\u00e9nico en la altura, Huaraz-Per\u00fa (3.100 M)","volume":"29","author":"L\u00f3pez De Guimaraes D","year":"2009","unstructured":"L\u00f3pez De Guimaraes D, Menacho L\u00f3pez J, Palacios JV, V\u00e1squez VM. Infarto Espl\u00e9nico en la altura, Huaraz-Per\u00fa (3.100 M). Revista de Gastroenterolog\u00eda del Peru. 2009, 29:179-184.","journal-title":"Revista de Gastroenterolog\u00eda del Peru"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1089\/ham.2018.0120","article-title":"Splenic infarct on exposure to extreme high altitude in individuals with sickle trait: a single-center experience","volume":"20","author":"Kumar R","year":"2019","unstructured":"Kumar R, Kapoor R, Singh J, Das S, Sharma A, Yanamandra U, Nair V. Splenic infarct on exposure to extreme high altitude in individuals with sickle trait: a single-center experience. High Alt Med Biol. 2019, 20:215-220. 10.1089\/ham.2018.0120","journal-title":"High Alt Med Biol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/33920-splenic-infarct-secondary-to-high-altitude-exposure-in-sickle-cell-trait-patients-a-case-series","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T19:24:47Z","timestamp":1707506687000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/33920-splenic-infarct-secondary-to-high-altitude-exposure-in-sickle-cell-trait-patients-a-case-series"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,17]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.9815","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8,17]]}}}