{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T02:30:51Z","timestamp":1764642651521,"version":"3.46.0"},"reference-count":11,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,1]]},"DOI":"10.7759\/cureus.98273","type":"journal-article","created":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T02:29:10Z","timestamp":1764642550000},"source":"Crossref","is-referenced-by-count":0,"title":["Gemcitabine-Induced Drug Rash With Eosinophilia and Systemic Symptoms (DRESS Syndrome): A Case Report"],"prefix":"10.7759","author":[{"given":"Sara","family":"Ait Elfaqir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Othmane","family":"Zouiten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leila","family":"Afani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"El Fadli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rhizlane","family":"Belbaraka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2011.01.017","article-title":"The DRESS syndrome: a literature review","volume":"124","author":"Cacoub P","year":"2011","unstructured":"Cacoub P, Musette P, Descamps V, Meyer O, Speirs C, Finzi L, Roujeau JC. The DRESS syndrome: a literature review. Am J Med. 2011, 124:588-97. 10.1016\/j.amjmed.2011.01.017","journal-title":"Am J Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22031127","article-title":"Drug reaction with eosinophilia and systemic symptoms: a complex interplay between drug, T cells, and herpesviridae","volume":"22","author":"Ganeshanandan L","year":"2021","unstructured":"Ganeshanandan L, Lucas M. Drug reaction with eosinophilia and systemic symptoms: a complex interplay between drug, T cells, and herpesviridae. Int J Mol Sci. 2021, 22:1127. 10.3390\/ijms22031127","journal-title":"Int J Mol Sci"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2013.05.002","article-title":"DRESS syndrome","volume":"81","author":"Descamps V","year":"2014","unstructured":"Descamps V, Ranger-Rogez S. DRESS syndrome. Joint Bone Spine. 2014, 81:15-21. 10.1016\/j.jbspin.2013.05.002","journal-title":"Joint Bone Spine"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02559.x","article-title":"Increased levels of interleukin 5 are associated with the generation of eosinophilia in drug-induced hypersensitivity syndrome","volume":"139","author":"Choquet-Kastylevsky G","year":"1998","unstructured":"Choquet-Kastylevsky G, Intrator L, Chenal C, Bocquet H, Revuz J, Roujeau JC. Increased levels of interleukin 5 are associated with the generation of eosinophilia in drug-induced hypersensitivity syndrome. Br J Dermatol. 1998, 139:1026-32. 10.1046\/j.1365-2133.1998.02559.x","journal-title":"Br J Dermatol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.07807.x","article-title":"The diagnosis of a DRESS syndrome has been sufficiently established on the basis of typical clinical features and viral reactivations","volume":"156","author":"Shiohara T","year":"2007","unstructured":"Shiohara T, Iijima M, Ikezawa Z, Hashimoto K. The diagnosis of a DRESS syndrome has been sufficiently established on the basis of typical clinical features and viral reactivations. Br J Dermatol. 2007, 156:1083-4. 10.1111\/j.1365-2133.2007.07807.x","journal-title":"Br J Dermatol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.fander.2020.07.003","article-title":"DRESS: drug reaction with eosinophilia and systemic symptoms (Article in French)","volume":"1","author":"Ingen-Housz-Oro S","year":"2021","unstructured":"Ingen-Housz-Oro S, Milpied B, Bensaid B, Descamps V . DRESS: drug reaction with eosinophilia and systemic symptoms (Article in French). Annales de Dermatologie et de V\u00e9n\u00e9r\u00e9ologie. 2021, 1:55-8. 10.1016\/j.fander.2020.07.003","journal-title":"Annales de Dermatologie et de V\u00e9n\u00e9r\u00e9ologie"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-199921060-00005","article-title":"Anticonvulsant hypersensitivity syndrome: incidence, prevention and management","volume":"21","author":"Knowles SR","year":"1999","unstructured":"Knowles SR, Shapiro LE, Shear NH. Anticonvulsant hypersensitivity syndrome: incidence, prevention and management. Drug Saf. 1999, 21:489-501. 10.2165\/00002018-199921060-00005","journal-title":"Drug Saf"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2008.03637.x","article-title":"Carbamazepine-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: report of four cases and brief review","volume":"47","author":"Ganeva M","year":"2008","unstructured":"Ganeva M, Gancheva T, Lazarova R, et al.. Carbamazepine-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: report of four cases and brief review. Int J Dermatol. 2008, 47:853-60. 10.1111\/j.1365-4632.2008.03637.x","journal-title":"Int J Dermatol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1994.12.9.1821","article-title":"Single-agent activity of weekly gemcitabine in advanced non-small-cell lung cancer: a phase II study","volume":"12","author":"Anderson H","year":"1994","unstructured":"Anderson H, Lund B, Bach F, Thatcher N, Walling J, Hansen HH. Single-agent activity of weekly gemcitabine in advanced non-small-cell lung cancer: a phase II study. J Clin Oncol. 1994, 12:1821-6. 10.1200\/JCO.1994.12.9.1821","journal-title":"J Clin Oncol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2003.11.023","article-title":"Phase II trial of gemcitabine as second-line chemotherapy of uterine leiomyosarcoma: a Gynecologic Oncology Group (GOG) Study","volume":"92","author":"Look KY","year":"2004","unstructured":"Look KY, Sandler A, Blessing JA, Lucci JA 3rd, Rose PG. Phase II trial of gemcitabine as second-line chemotherapy of uterine leiomyosarcoma: a Gynecologic Oncology Group (GOG) Study. Gynecol Oncol. 2004, 92:644-7. 10.1016\/j.ygyno.2003.11.023","journal-title":"Gynecol Oncol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2006.07704.x","article-title":"Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: does a DRESS syndrome really exist?","volume":"156","author":"Kardaun SH","year":"2007","unstructured":"Kardaun SH, Sidoroff A, Valeyrie-Allanore L, Halevy S, Davidovici BB, Mockenhaupt M, Roujeau JC. Variability in the clinical pattern of cutaneous side-effects of drugs with systemic symptoms: does a DRESS syndrome really exist?. Br J Dermatol. 2007, 156:609-11. 10.1111\/j.1365-2133.2006.07704.x","journal-title":"Br J Dermatol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/428510-gemcitabine-induced-drug-rash-with-eosinophilia-and-systemic-symptoms-dress-syndrome-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T02:29:14Z","timestamp":1764642554000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/428510-gemcitabine-induced-drug-rash-with-eosinophilia-and-systemic-symptoms-dress-syndrome-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,1]]},"references-count":11,"URL":"https:\/\/doi.org\/10.7759\/cureus.98273","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,1]]}}}