{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T09:08:31Z","timestamp":1765012111734,"version":"3.46.0"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,6]]},"DOI":"10.7759\/cureus.98561","type":"journal-article","created":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T09:04:13Z","timestamp":1765011853000},"source":"Crossref","is-referenced-by-count":0,"title":["Outcomes of Early Extubation Following Fontan Surgery in Children: A Systematic Review and Meta-Analysis"],"prefix":"10.7759","author":[{"given":"Ahmed M","family":"Omran","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed  M","family":"Elabd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000696","article-title":"Evaluation and management of the child and adult with Fontan circulation: a scientific statement from the American Heart Association","volume":"140","author":"Rychik J","year":"2019","unstructured":"Rychik J, Atz AM, Celermajer DS, et al.. Evaluation and management of the child and adult with Fontan circulation: a scientific statement from the American Heart Association. Circulation. 2019, 140:e234-84. 10.1161\/CIR.0000000000000696","journal-title":"Circulation"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3390\/children8060441","article-title":"Single ventricle-a comprehensive review","volume":"8","author":"Rao PS","year":"2021","unstructured":"Rao PS. Single ventricle-a comprehensive review. Children (Basel). 2021, 8:441. 10.3390\/children8060441","journal-title":"Children (Basel)"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjae.2021.01.002","article-title":"The cardiovascular effects of positive pressure ventilation","volume":"21","author":"Corp A","year":"2021","unstructured":"Corp A, Thomas C, Adlam M. The cardiovascular effects of positive pressure ventilation. BJA Educ. 2021, 21:202-9. 10.1016\/j.bjae.2021.01.002","journal-title":"BJA Educ"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2020-316613","article-title":"Augmentation of pulmonary blood flow and cardiac output by non-invasive external ventilation late after Fontan palliation","volume":"107","author":"Charla P","year":"2021","unstructured":"Charla P, Karur GR, Yamamura K, et al.. Augmentation of pulmonary blood flow and cardiac output by non-invasive external ventilation late after Fontan palliation. Heart. 2021, 107:142-9. 10.1136\/heartjnl-2020-316613","journal-title":"Heart"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.17085\/apm.23154","article-title":"Early extubation after pediatric cardiac surgery","volume":"19","author":"Tham SQ","year":"2024","unstructured":"Tham SQ, Lim EH. Early extubation after pediatric cardiac surgery. Anesth Pain Med (Seoul). 2024, 19:S61-72. 10.17085\/apm.23154","journal-title":"Anesth Pain Med (Seoul)"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s12055-020-00924-1","article-title":"Fast tracking after repair of congenital heart defects","volume":"37","author":"Garg RK","year":"2021","unstructured":"Garg RK, Thareen JK, Mehmood A, et al.. Fast tracking after repair of congenital heart defects. Indian J Thorac Cardiovasc Surg. 2021, 37:183-9. 10.1007\/s12055-020-00924-1","journal-title":"Indian J Thorac Cardiovasc Surg"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezy179","article-title":"Early extubation is associated with improved early outcome after extracardiac total cavopulmonary connection independently of duration of cardiopulmonary bypass","volume":"54","author":"Ovroutski S","year":"2018","unstructured":"Ovroutski S, Kramer P, Nordmeyer S, et al.. Early extubation is associated with improved early outcome after extracardiac total cavopulmonary connection independently of duration of cardiopulmonary bypass. Eur J Cardiothorac Surg. 2018, 54:953-8. 10.1093\/ejcts\/ezy179","journal-title":"Eur J Cardiothorac Surg"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-016-1406-7","article-title":"Impact and challenges of a policy change to early track extubation in the operating room for Fontan","volume":"37","author":"Kawaguchi A","year":"2016","unstructured":"Kawaguchi A, Liu Q, Coquet S, Yasui Y, Cave D. Impact and challenges of a policy change to early track extubation in the operating room for Fontan. Pediatr Cardiol. 2016, 37:1127-36. 10.1007\/s00246-016-1406-7","journal-title":"Pediatr Cardiol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivz010","article-title":"Early extubation improves outcome following extracardiac total cavopulmonary connection","volume":"29","author":"Ono M","year":"2019","unstructured":"Ono M, Georgiev S, Burri M, et al.. Early extubation improves outcome following extracardiac total cavopulmonary connection. Interact Cardiovasc Thorac Surg. 2019, 29:85-92. 10.1093\/icvts\/ivz010","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-018-1986-5","article-title":"Extubation in the operating room after Fontan procedure: does it make a difference?","volume":"40","author":"Kintrup S","year":"2019","unstructured":"Kintrup S, Malec E, Kiski D, et al.. Extubation in the operating room after Fontan procedure: does it make a difference?. Pediatr Cardiol. 2019, 40:468-76. 10.1007\/s00246-018-1986-5","journal-title":"Pediatr Cardiol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-14-135","article-title":"Estimating the sample mean and standard deviation from the sample size, median, range and\/or interquartile range","volume":"14","author":"Wan X","year":"2014","unstructured":"Wan X, Wang W, Liu J, Tong T. Estimating the sample mean and standard deviation from the sample size, median, range and\/or interquartile range. BMC Med Res Methodol. 2014, 14:135. 10.1186\/1471-2288-14-135","journal-title":"BMC Med Res Methodol"},{"key":"ref12","article-title":"Higgins JPT, Thomas J, Chandler J, et al.","author":"Higgins JPT","year":"2019","unstructured":"Higgins JPT, Thomas J, Chandler J, et al.. Cochrane Handbook for Systematic Reviews of Interventions version 6.5. John Wiley &amp; Sons, Chichester (UK); 2019. https:\/\/www.cochrane.org\/authors\/handbooks-and-manuals\/handbook#how-to-access."},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i4919","article-title":"ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne JA","year":"2016","unstructured":"Sterne JA, Hern\u00e1n MA, Reeves BC, et al.. ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 2016, 355:i4919. 10.1136\/bmj.i4919","journal-title":"BMJ"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.328.7454.1490","article-title":"Grading quality of evidence and strength of recommendations","volume":"328","author":"Atkins D","year":"2004","unstructured":"Atkins D, Best D, Briss PA, et al.. Grading quality of evidence and strength of recommendations. BMJ. 2004, 328:1490. 10.1136\/bmj.328.7454.1490","journal-title":"BMJ"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2008.11.011","article-title":"A randomized trial of outcomes of anesthetic management directed to very early extubation after cardiac surgery in children","volume":"23","author":"Preisman S","year":"2009","unstructured":"Preisman S, Lembersky H, Yusim Y, Raviv-Zilka L, Perel A, Keidan I, Mishaly D. A randomized trial of outcomes of anesthetic management directed to very early extubation after cardiac surgery in children. J Cardiothorac Vasc Anesth. 2009, 23:348-57. 10.1053\/j.jvca.2008.11.011","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000002006","article-title":"Spontaneous breathing trial for prediction of extubation success in pediatric patients following congenital heart surgery: a randomized controlled trial","volume":"20","author":"Ferreira FV","year":"2019","unstructured":"Ferreira FV, Sugo EK, Aragon DC, Carmona F, Carlotti AP. Spontaneous breathing trial for prediction of extubation success in pediatric patients following congenital heart surgery: a randomized controlled trial. Pediatr Crit Care Med. 2019, 20:940-6. 10.1097\/PCC.0000000000002006","journal-title":"Pediatr Crit Care Med"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.14740\/cr2029","article-title":"Achieving neuroprotection in the setting of early extubation during infant cardiac surgery: a prospective, randomized, and blinded study","volume":"16","author":"Naguib AN","year":"2025","unstructured":"Naguib AN, Bozych M, McNally K, Galantowicz M, Tobias J. Achieving neuroprotection in the setting of early extubation during infant cardiac surgery: a prospective, randomized, and blinded study. Cardiol Res. 2025, 16:178-88. 10.14740\/cr2029","journal-title":"Cardiol Res"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)61872-3","article-title":"Early extubation following pediatric cardiothoracic operation: a viable alternative","volume":"29","author":"Barash","year":"1980","unstructured":"Barash, P. G., Lescovich, et al.. Early extubation following pediatric cardiothoracic operation: a viable alternative. The Annals of Thoracic Surgery. 1980, 29:228-33. 10.1016\/S0003-4975(10)61872-3","journal-title":"The Annals of Thoracic Surgery"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2008.02.010","article-title":"Extubation in the operating room after Fontan's procedure: effect on practice and outcomes","volume":"86","author":"Morales DL","year":"2008","unstructured":"Morales DL, Carberry KE, Heinle JS, McKenzie ED, Fraser CD Jr, Diaz LK. Extubation in the operating room after Fontan's procedure: effect on practice and outcomes. Ann Thorac Surg. 2008, 86:576-81; discussion 581-2. 10.1016\/j.athoracsur.2008.02.010","journal-title":"Ann Thorac Surg"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-1743177","article-title":"Early extubation in children after cardiac surgery. Initial experience from a tertiary care hospital in Mexico City","volume":"13","author":"Figueroa-Solano J","year":"2024","unstructured":"Figueroa-Solano J, Infante-S\u00e1nchez K, Espinosa-Guerra K, et al.. Early extubation in children after cardiac surgery. Initial experience from a tertiary care hospital in Mexico City. J Pediatr Intensive Care. 2024, 13:337-43. 10.1055\/s-0042-1743177","journal-title":"J Pediatr Intensive Care"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8191.2010.01088.x","article-title":"Early extubation after pediatric cardiac surgery: systematic review, meta-analysis, and evidence-based recommendations","volume":"25","author":"Alghamdi AA","year":"2010","unstructured":"Alghamdi AA, Singh SK, Hamilton BC, Yadava M, Holtby H, Van Arsdell GS, Al-Radi OO. Early extubation after pediatric cardiac surgery: systematic review, meta-analysis, and evidence-based recommendations. J Card Surg. 2010, 25:586-95. 10.1111\/j.1540-8191.2010.01088.x","journal-title":"J Card Surg"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.64216","article-title":"The complex interplay of variables in extubation decision-making following pediatric cardiac surgery: a narrative review","volume":"16","author":"Durai Samy NK","year":"2024","unstructured":"Durai Samy NK, Taksande K. The complex interplay of variables in extubation decision-making following pediatric cardiac surgery: a narrative review. Cureus. 2024, 16:e64216. 10.7759\/cureus.64216","journal-title":"Cureus"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1111\/pan.70026","article-title":"On-table extubation after pediatric cardiac surgery: a systematic review","author":"Tapioca V","year":"2025","unstructured":"Tapioca V, Caetano L, Gibicoski T, Alrayashi W, Amaral S. On-table extubation after pediatric cardiac surgery: a systematic review. Paediatr Anaesth. 2025, 10.1111\/pan.70026","journal-title":"Paediatr Anaesth"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/426622-outcomes-of-early-extubation-following-fontan-surgery-in-children-a-systematic-review-and-meta-analysis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T09:04:14Z","timestamp":1765011854000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/426622-outcomes-of-early-extubation-following-fontan-surgery-in-children-a-systematic-review-and-meta-analysis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,6]]},"references-count":23,"URL":"https:\/\/doi.org\/10.7759\/cureus.98561","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,6]]}}}