{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T16:24:59Z","timestamp":1765124699882,"version":"3.46.0"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,7]]},"DOI":"10.7759\/cureus.98638","type":"journal-article","created":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T16:22:08Z","timestamp":1765124528000},"source":"Crossref","is-referenced-by-count":0,"title":["Allgrove Syndrome in Adults: A Case of an Atypical Presentation"],"prefix":"10.7759","author":[{"given":"Meryem","family":"Maizi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatima","family":"Belabbes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanane","family":"Delsa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saloua","family":"Elamari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imane","family":"Ben Elbarhdadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(78)91268-0","article-title":"Familial glucocorticoid deficiency with achalasia of the cardia and deficient tear production","volume":"17","author":"Allgrove J","year":"1978","unstructured":"Allgrove J, Clayden GS, Grant DB, Macaulay JC. Familial glucocorticoid deficiency with achalasia of the cardia and deficient tear production. Lancet. 1978, 17:1284-6. 10.1016\/s0140-6736(78)91268-0","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000533894","article-title":"Triple-A syndrome in Morocco: founder effect, age estimation of the AAAS c.1331+1G&gt;A variant, and implications for genetic diagnosis","volume":"15","author":"Belmokhtar KY","year":"2024","unstructured":"Belmokhtar KY, Cherkaoui I, Lhousni S, et al.. Triple-A syndrome in Morocco: founder effect, age estimation of the AAAS c.1331+1G&amp;gt;A variant, and implications for genetic diagnosis. Mol Syndromol. 2024, 15:96-103. 10.1159\/000533894","journal-title":"Mol Syndromol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurol.2024.02.205","article-title":"Allgrove syndrome involving motor neuron involvement: a study of a Moroccan family (Article in French)","volume":"180","author":"Ouhabi D","year":"2024","unstructured":"Ouhabi D, Tamaoui L, Marzouk B, Kably B, Birouk N. Allgrove syndrome involving motor neuron involvement: a study of a Moroccan family (Article in French). Revue Neurologique. 2024, 180:S105. 10.1016\/j.neurol.2024.02.205","journal-title":"Revue Neurologique"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1530\/EC-17-0255","article-title":"Phenotype-genotype spectrum of AAA syndrome from Western India and systematic review of literature","volume":"6","author":"Patt H","year":"2017","unstructured":"Patt H, Koehler K, Lodha S, et al.. Phenotype-genotype spectrum of AAA syndrome from Western India and systematic review of literature. Endocr Connect. 2017, 6:901-13. 10.1530\/EC-17-0255","journal-title":"Endocr Connect"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ando.2016.07.189","article-title":"Founder effect and estimation of the founder mutation age in three Maghreb countries: a study of 66 patients with Allgrove syndrome (Article in French)","volume":"77","author":"Kallabi F","year":"2016","unstructured":"Kallabi F, Tebaibia A, Boudjella L, et al.. Founder effect and estimation of the founder mutation age in three Maghreb countries: a study of 66 patients with Allgrove syndrome (Article in French). Annales d'Endocrinologie. 2016, 77:309-10. 10.1016\/j.ando.2016.07.189","journal-title":"Annales d'Endocrinologie"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.26815\/acn.2024.00458","article-title":"Neurological characteristics of Allgrove syndrome: a case series","volume":"32","author":"Salah DB","year":"2024","unstructured":"Salah DB, Elleuch M, Trimeche O, et al.. Neurological characteristics of Allgrove syndrome: a case series. Ann Child Neurol. 2024, 32:130-4. 10.26815\/acn.2024.00458","journal-title":"Ann Child Neurol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0124582","article-title":"Role of ALADIN in human adrenocortical cells for oxidative stress response and steroidogenesis","volume":"10","author":"J\u00fchlen R","year":"2015","unstructured":"J\u00fchlen R, Idkowiak J, Taylor AE, Kind B, Arlt W, Huebner A, Koehler K. Role of ALADIN in human adrenocortical cells for oxidative stress response and steroidogenesis. PLoS One. 2015, 10:e0124582. 10.1371\/journal.pone.0124582","journal-title":"PLoS One"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.19316","article-title":"Mineralocorticoid deficiency as an early presenting symptom of Allgrove syndrome with novel mutation: a case report","volume":"13","author":"AlOmran HA","year":"2021","unstructured":"AlOmran HA, Busaleh F, Alhashim Z, et al.. Mineralocorticoid deficiency as an early presenting symptom of Allgrove syndrome with novel mutation: a case report. Cureus. 2021, 13:e19316. 10.7759\/cureus.19316","journal-title":"Cureus"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2015.20.359.4717","article-title":"Congenital alacrima revealing an Allgrove syndrome: report of three cases (Article in French)","volume":"20","author":"Derrar R","year":"2015","unstructured":"Derrar R, Boutimzine N, Laghmari A, Alouane A, Daoudi R. Congenital alacrima revealing an Allgrove syndrome: report of three cases (Article in French). Pan Afr Med J. 2015, 20:359. 10.11604\/pamj.2015.20.359.4717","journal-title":"Pan Afr Med J"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-011-6115-9","article-title":"Neurological features in adult Triple-A (Allgrove) syndrome","volume":"259","author":"Vallet AE","year":"2012","unstructured":"Vallet AE, Verschueren A, Petiot P, et al.. Neurological features in adult Triple-A (Allgrove) syndrome. J Neurol. 2012, 259:39-46. 10.1007\/s00415-011-6115-9","journal-title":"J Neurol"},{"key":"ref11","article-title":"Allgrove syndrome","author":"Sheikh MM","year":"2025","unstructured":"Sheikh MM, Bittar K. Allgrove syndrome. StatPearls [Internet]. StatPearls Publishing, Treasure Island (FL); 2025."},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1210\/en.2013-1241","article-title":"Deficiency of ALADIN impairs redox homeostasis in human adrenal cells and inhibits steroidogenesis","volume":"154","author":"Prasad R","year":"2013","unstructured":"Prasad R, Metherell LA, Clark AJ, Storr HL. Deficiency of ALADIN impairs redox homeostasis in human adrenal cells and inhibits steroidogenesis. Endocrinology. 2013, 154:3209-18. 10.1210\/en.2013-1241","journal-title":"Endocrinology"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/BF01946264","article-title":"Studies on the physiology and pathology of tear secretion and tear drainage (Article in German)","volume":"56","author":"Schirmer O","year":"1903","unstructured":"Schirmer O. Studies on the physiology and pathology of tear secretion and tear drainage (Article in German). Graefes Arhiv f\u00fcr Ophthalmologie. 1903, 56:197-291. 10.1007\/BF01946264","journal-title":"Graefes Arhiv f\u00fcr Ophthalmologie"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.14058","article-title":"Esophageal motility disorders on high-resolution manometry: Chicago classification version 4.0(\u00a9)","volume":"33","author":"Yadlapati R","year":"2021","unstructured":"Yadlapati R, Kahrilas PJ, Fox MR, et al.. Esophageal motility disorders on high-resolution manometry: Chicago classification version 4.0(\u00a9). Neurogastroenterol Motil. 2021, 33:e14058. 10.1111\/nmo.14058","journal-title":"Neurogastroenterol Motil"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/421579-allgrove-syndrome-in-adults-a-case-of-an-atypical-presentation","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,7]],"date-time":"2025-12-07T16:22:09Z","timestamp":1765124529000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/421579-allgrove-syndrome-in-adults-a-case-of-an-atypical-presentation"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,7]]},"references-count":14,"URL":"https:\/\/doi.org\/10.7759\/cureus.98638","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,7]]}}}