{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T01:15:35Z","timestamp":1790558135920,"version":"4.1.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,13]]},"DOI":"10.7759\/cureus.99172","type":"journal-article","created":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T06:56:41Z","timestamp":1765695401000},"source":"Crossref","is-referenced-by-count":1,"title":["Osteoporosis in Patients With Marfan Syndrome: A Narrative Review of Bone Health and Management"],"prefix":"10.7759","author":[{"given":"Abdul Waheed","family":"Bahir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munir Ahmad","family":"Bahir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qudratullah","family":"Bahir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gu","family":"Shao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiong","family":"Ying","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2014.03.007","article-title":"Osteoporosis and its complications","volume":"98","author":"Varacallo MA","year":"2014","unstructured":"Varacallo MA, Fox EJ. Osteoporosis and its complications. Med Clin North Am. 2014, 98:817-31. 10.1016\/j.mcna.2014.03.007","journal-title":"Med Clin North Am"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.35540","article-title":"Assessment of bone mineral status in children with Marfan syndrome","volume":"158A","author":"Grover M","year":"2012","unstructured":"Grover M, Brunetti-Pierri N, Belmont J, et al.. Assessment of bone mineral status in children with Marfan syndrome. Am J Med Genet A. 2012, 158A:2221-4. 10.1002\/ajmg.a.35540","journal-title":"Am J Med Genet A"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrrev.2015.04.002","article-title":"Engineered mutations in fibrillin-1 leading to Marfan syndrome act at the protein, cellular and organismal levels","volume":"765","author":"Zeyer KA","year":"2015","unstructured":"Zeyer KA, Reinhardt DP. Engineered mutations in fibrillin-1 leading to Marfan syndrome act at the protein, cellular and organismal levels. Mutat Res Rev Mutat Res. 2015, 765:7-18. 10.1016\/j.mrrev.2015.04.002","journal-title":"Mutat Res Rev Mutat Res"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.29800","article-title":"Cardiac complications in Marfan syndrome: a review","volume":"14","author":"Singh J","year":"2022","unstructured":"Singh J, Wanjari A. Cardiac complications in Marfan syndrome: a review. Cureus. 2022, 14:e29800. 10.7759\/cureus.29800","journal-title":"Cureus"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd11040114","article-title":"Unique features of cardiovascular involvement and progression in children with Marfan syndrome justify dedicated multidisciplinary care","volume":"11","author":"Baban A","year":"2024","unstructured":"Baban A, Parlapiano G, Cicenia M, et al.. Unique features of cardiovascular involvement and progression in children with Marfan syndrome justify dedicated multidisciplinary care. J Cardiovasc Dev Dis. 2024, 11:4. 10.3390\/jcdd11040114","journal-title":"J Cardiovasc Dev Dis"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s40199-017-0167-z","article-title":"New horizons in treatment of osteoporosis","volume":"25","author":"Tabatabaei-Malazy O","year":"2017","unstructured":"Tabatabaei-Malazy O, Salari P, Khashayar P, Larijani B. New horizons in treatment of osteoporosis. Daru. 2017, 25:2. 10.1186\/s40199-017-0167-z","journal-title":"Daru"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-382040-2.10018-8","article-title":"The spectrum of pediatric osteoporosis","author":"Bianchi ML","year":"2012","unstructured":"Bianchi ML, Glorieux FH. The spectrum of pediatric osteoporosis. Pediatric Bone. Elsevier, Amsterdam, Netherlands; 2012. 1016:978. 10.1016\/B978-0-12-382040-2.10018-8"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.10.039","article-title":"Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in Marfan syndrome","volume":"140","author":"Yang HH","year":"2010","unstructured":"Yang HH, Kim JM, Chum E, van Breemen C, Chung AW. Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in Marfan syndrome. J Thorac Cardiovasc Surg. 2010, 140:305-12. 10.1016\/j.jtcvs.2009.10.039","journal-title":"J Thorac Cardiovasc Surg"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.13140\/RG.2.1.4031.4087","article-title":"The meaning of living with osteoporosis","author":"Hovey RB","year":"2006","unstructured":"Hovey RB. The meaning of living with osteoporosis. 2006. 10.13140\/RG.2.1.4031.4087"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.cdtm.2015.02.006","article-title":"Primary osteoporosis in postmenopausal women","volume":"1","author":"Ji MX","year":"2015","unstructured":"Ji MX, Yu Q. Primary osteoporosis in postmenopausal women. Chronic Dis Transl Med. 2015, 1:9-13. 10.1016\/j.cdtm.2015.02.006","journal-title":"Chronic Dis Transl Med"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3390\/genes11050574","article-title":"Quantifying the genetic basis of Marfan syndrome clinical variability","volume":"11","author":"Grange T","year":"2020","unstructured":"Grange T, Aubart M, Langeois M, et al.. Quantifying the genetic basis of Marfan syndrome clinical variability. Genes (Basel). 2020, 11:4. 10.3390\/genes11050574","journal-title":"Genes (Basel)"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2018.07.016","article-title":"Fibrillin microfibrils and elastic fibre proteins: functional interactions and extracellular regulation of growth factors","volume":"89","author":"Thomson J","year":"2019","unstructured":"Thomson J, Singh M, Eckersley A, Cain SA, Sherratt MJ, Baldock C. Fibrillin microfibrils and elastic fibre proteins: functional interactions and extracellular regulation of growth factors. Semin Cell Dev Biol. 2019, 89:109-17. 10.1016\/j.semcdb.2018.07.016","journal-title":"Semin Cell Dev Biol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13132284","article-title":"Marfan syndrome: enhanced diagnostic tools and follow-up management strategies","volume":"13","author":"Marelli S","year":"2023","unstructured":"Marelli S, Micaglio E, Taurino J, et al.. Marfan syndrome: enhanced diagnostic tools and follow-up management strategies. Diagnostics (Basel). 2023, 13:4. 10.3390\/diagnostics13132284","journal-title":"Diagnostics (Basel)"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.4103\/jovr.jovr_29_18","article-title":"Management strategies of ocular abnormalities in patients with Marfan syndrome: current perspective","volume":"14","author":"Esfandiari H","year":"2019","unstructured":"Esfandiari H, Ansari S, Mohammad-Rabei H, Mets MB. Management strategies of ocular abnormalities in patients with Marfan syndrome: current perspective. J Ophthalmic Vis Res. 2019, 14:71-7. 10.4103\/jovr.jovr_29_18","journal-title":"J Ophthalmic Vis Res"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-021-00298-7","article-title":"Marfan syndrome","volume":"7","author":"Milewicz DM","year":"2021","unstructured":"Milewicz DM, Braverman AC, De Backer J, et al.. Marfan syndrome. Nat Rev Dis Primers. 2021, 7:64. 10.1038\/s41572-021-00298-7","journal-title":"Nat Rev Dis Primers"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-92042-5","article-title":"Clinical Guide to Musculoskeletal Medicine: A Multidisciplinary Approach","author":"Mostoufi SA","year":"2022","unstructured":"Mostoufi SA, George TK, Tria AJ,. Clinical Guide to Musculoskeletal Medicine: A Multidisciplinary Approach. Springer International Publishing, Cham, Switzerland; 2022. 10.1007\/978-3-030-92042-5"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.admecli.2004.06.002","article-title":"Chest wall anomalies: pectus excavatum and pectus carinatum","volume":"15","author":"Goretsky MJ","year":"2004","unstructured":"Goretsky MJ, Kelly RE Jr, Croitoru D, Nuss D. Chest wall anomalies: pectus excavatum and pectus carinatum. Adolesc Med Clin. 2004, 15:455-71. 10.1016\/j.admecli.2004.06.002","journal-title":"Adolesc Med Clin"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-80614-9_9","article-title":"Ehlers-Danlos syndromes, joint hypermobility and hypermobility spectrum disorders","volume":"1348","author":"Micale L","year":"2021","unstructured":"Micale L, Fusco C, Castori M. Ehlers-Danlos syndromes, joint hypermobility and hypermobility spectrum disorders. Adv Exp Med Biol. 2021, 1348:207-33. 10.1007\/978-3-030-80614-9_9","journal-title":"Adv Exp Med Biol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.4258","article-title":"Fracture rates and fracture risk in patients with Marfan syndrome: a nationwide register-based cohort study","volume":"36","author":"Folkestad L","year":"2021","unstructured":"Folkestad L, Stochholm K, Groth K, Hove H, Andersen NH, Gravholt CH. Fracture rates and fracture risk in patients with Marfan syndrome: a nationwide register-based cohort study. J Bone Miner Res. 2021, 36:901-9. 10.1002\/jbmr.4258","journal-title":"J Bone Miner Res"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1038\/s41436-018-0399-4","article-title":"Marfan syndrome: improved clinical history results in expanded natural history","volume":"21","author":"Pyeritz RE","year":"2019","unstructured":"Pyeritz RE. Marfan syndrome: improved clinical history results in expanded natural history. Genet Med. 2019, 21:1683-90. 10.1038\/s41436-018-0399-4","journal-title":"Genet Med"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2012.07.023","article-title":"Structure and function of the mammalian fibrillin gene family: implications for human connective tissue diseases","volume":"107","author":"Davis MR","year":"2012","unstructured":"Davis MR, Summers KM. Structure and function of the mammalian fibrillin gene family: implications for human connective tissue diseases. Mol Genet Metab. 2012, 107:635-47. 10.1016\/j.ymgme.2012.07.023","journal-title":"Mol Genet Metab"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.30574\/gscbps.2021.14.2.0054","article-title":"Osteoporosis and lifestyle medicine","volume":"14","author":"Mahadik AB","year":"2021","unstructured":"Mahadik AB, Giri AB, Bhambre AS, Mundhe SA, Ramdas D. Osteoporosis and lifestyle medicine. GSC Biol and Pharm Sci. 2021, 14:155-65. 10.30574\/gscbps.2021.14.2.0054","journal-title":"GSC Biol and Pharm Sci"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2013.4611","article-title":"Osteoporosis prevention, screening, and treatment: a review","volume":"23","author":"Kling JM","year":"2014","unstructured":"Kling JM, Clarke BL, Sandhu NP. Osteoporosis prevention, screening, and treatment: a review. J Womens Health (Larchmt). 2014, 23:563-72. 10.1089\/jwh.2013.4611","journal-title":"J Womens Health (Larchmt)"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1086\/520125","article-title":"Effect of mutation type and location on clinical outcome in 1,013 probands with Marfan syndrome or related phenotypes and FBN1 mutations: an international study","volume":"81","author":"Faivre L","year":"2007","unstructured":"Faivre L, Collod-Beroud G, Loeys BL, et al.. Effect of mutation type and location on clinical outcome in 1,013 probands with Marfan syndrome or related phenotypes and FBN1 mutations: an international study. Am J Hum Genet. 2007, 81:454-66. 10.1086\/520125","journal-title":"Am J Hum Genet"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2008.10.006","article-title":"Stem cell regulation via dynamic interactions of the nervous and immune systems with the microenvironment","volume":"3","author":"Spiegel A","year":"2008","unstructured":"Spiegel A, Kalinkovich A, Shivtiel S, Kollet O, Lapidot T. Stem cell regulation via dynamic interactions of the nervous and immune systems with the microenvironment. Cell Stem Cell. 2008, 3:484-92. 10.1016\/j.stem.2008.10.006","journal-title":"Cell Stem Cell"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1111\/cge.12436","article-title":"Cardiovascular manifestations in Marfan syndrome and related diseases; multiple genes causing similar phenotypes","volume":"87","author":"Cook JR","year":"2015","unstructured":"Cook JR, Carta L, Galatioto J, Ramirez F. Cardiovascular manifestations in Marfan syndrome and related diseases; multiple genes causing similar phenotypes. Clin Genet. 2015, 87:11-20. 10.1111\/cge.12436","journal-title":"Clin Genet"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-021-01045-3","article-title":"The musculoskeletal manifestations of Marfan syndrome: diagnosis, impact, and management","volume":"23","author":"Pollock L","year":"2021","unstructured":"Pollock L, Ridout A, Teh J, et al.. The musculoskeletal manifestations of Marfan syndrome: diagnosis, impact, and management. Curr Rheumatol Rep. 2021, 23:81. 10.1007\/s11926-021-01045-3","journal-title":"Curr Rheumatol Rep"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2005.039669","article-title":"The molecular genetics of Marfan syndrome and related disorders","volume":"43","author":"Robinson PN","year":"2006","unstructured":"Robinson PN, Arteaga-Solis E, Baldock C, et al.. The molecular genetics of Marfan syndrome and related disorders. J Med Genet. 2006, 43:769-87. 10.1136\/jmg.2005.039669","journal-title":"J Med Genet"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-80614-9_8","article-title":"Pathophysiology and Pathogenesis of Marfan Syndrome","volume":"1348","author":"Zeigler SM","year":"2021","unstructured":"Zeigler SM, Sloan B, Jones JA. Pathophysiology and Pathogenesis of Marfan Syndrome. Adv Exp Med Biol. 2021, 1348:185-206. 10.1007\/978-3-030-80614-9_8","journal-title":"Adv Exp Med Biol"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.4236\/ojs.2019.92017","article-title":"Constructing prediction intervals: a re-edition of the Williams-Goodman method","volume":"9","author":"Amerise IL","year":"2019","unstructured":"Amerise IL, Tarsitano A. Constructing prediction intervals: a re-edition of the Williams-Goodman method. OJS. 2019, 9:230-44. 10.4236\/ojs.2019.92017","journal-title":"OJS"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-84882-085-2","article-title":"Hypermobility of Joints","author":"Beighton PH","year":"2012","unstructured":"Beighton PH, Grahame R, Bird H. Hypermobility of Joints. Springer, London, UK; 2012. 10.1007\/978-1-84882-085-2"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.120.256180","article-title":"Bone mineral density: clinical relevance and quantitative assessment","volume":"62","author":"Haseltine KN","year":"2021","unstructured":"Haseltine KN, Chukir T, Smith PJ, Jacob JT, Bilezikian JP, Farooki A. Bone mineral density: clinical relevance and quantitative assessment. J Nucl Med. 2021, 62:446-54. 10.2967\/jnumed.120.256180","journal-title":"J Nucl Med"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.14288\/1.0371940","article-title":"The transition to adulthood in adolescents and young adults with Marfan Syndrome : a scoping review","author":"Ng TA","year":"2018","unstructured":"Ng TA. The transition to adulthood in adolescents and young adults with Marfan Syndrome : a scoping review. UBC Libr Open Collect. 2018, 10.14288\/1.0371940","journal-title":"UBC Libr Open Collect"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4419-9013-6","article-title":"Marfan Syndrome: A Primer for Clinicians and Scientists","author":"Robinson PN","year":"2004","unstructured":"Robinson PN, Godfrey M. Marfan Syndrome: A Primer for Clinicians and Scientists. Landes Bioscience, Georgetown, TX; 2004. 10.1007\/978-1-4419-9013-6"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1186\/s40364-017-0097-4","article-title":"Bone biomarker for the clinical assessment of osteoporosis: recent developments and future perspectives","volume":"5","author":"Kuo TR","year":"2017","unstructured":"Kuo TR, Chen CH. Bone biomarker for the clinical assessment of osteoporosis: recent developments and future perspectives. Biomark Res. 2017, 5:18. 10.1186\/s40364-017-0097-4","journal-title":"Biomark Res"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCGEN.117.002039","article-title":"Tailoring the American College of Medical Genetics and Genomics and the Association for Molecular Pathology guidelines for the interpretation of sequenced variants in the FBN1 gene for Marfan syndrome: proposal for a disease- and gene-specific guideline","volume":"11","author":"Mui\u00f1o-Mosquera L","year":"2018","unstructured":"Mui\u00f1o-Mosquera L, Steijns F, Audenaert T, et al.. Tailoring the American College of Medical Genetics and Genomics and the Association for Molecular Pathology guidelines for the interpretation of sequenced variants in the FBN1 gene for Marfan syndrome: proposal for a disease- and gene-specific guideline. Circ Genom Precis Med. 2018, 11:e002039. 10.1161\/CIRCGEN.117.002039","journal-title":"Circ Genom Precis Med"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1177\/1759720X221083541","article-title":"Osteoporosis in 10 years time: a glimpse into the future of osteoporosis","volume":"14","author":"Adami G","year":"2022","unstructured":"Adami G, Fassio A, Gatti D, et al.. Osteoporosis in 10 years time: a glimpse into the future of osteoporosis. Ther Adv Musculoskelet Dis. 2022, 14:1. 10.1177\/1759720X221083541","journal-title":"Ther Adv Musculoskelet Dis"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.4137\/CMAMD.S10279","article-title":"Musculo-skeletal abnormalities in patients with Marfan syndrome","volume":"6","author":"Al Kaissi A","year":"2013","unstructured":"Al Kaissi A, Zwettler E, Ganger R, Schreiner S, Klaushofer K, Grill F. Musculo-skeletal abnormalities in patients with Marfan syndrome. Clin Med Insights Arthritis Musculoskelet Disord. 2013, 6:1-9. 10.4137\/CMAMD.S10279","journal-title":"Clin Med Insights Arthritis Musculoskelet Disord"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1080\/14779072.2019.1704625","article-title":"Features of Marfan syndrome not listed in the Ghent nosology - the dark side of the disease","volume":"17","author":"von Kodolitsch Y","year":"2019","unstructured":"von Kodolitsch Y, Demolder A, Girdauskas E, et al.. Features of Marfan syndrome not listed in the Ghent nosology - the dark side of the disease. Expert Rev Cardiovasc Ther. 2019, 17:883-915. 10.1080\/14779072.2019.1704625","journal-title":"Expert Rev Cardiovasc Ther"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.2147\/JEP.S265271","article-title":"An overview of investigational and experimental drug treatment strategies for Marfan syndrome","volume":"13","author":"Deleeuw V","year":"2021","unstructured":"Deleeuw V, De Clercq A, De Backer J, Sips P. An overview of investigational and experimental drug treatment strategies for Marfan syndrome. J Exp Pharmacol. 2021, 13:755-79. 10.2147\/JEP.S265271","journal-title":"J Exp Pharmacol"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.3c08977","article-title":"Molecularly imprinted polymers: shaping the future of early-stage bone loss detection\u2014a review","volume":"9","author":"Agnishwaran B","year":"2024","unstructured":"Agnishwaran B, Manivasagam G, Udduttula A. Molecularly imprinted polymers: shaping the future of early-stage bone loss detection\u2014a review. ACS Omega. 2024, 9:8730-42. 10.1021\/acsomega.3c08977","journal-title":"ACS Omega"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2017-02163","article-title":"A phase III randomized placebo-controlled trial to evaluate efficacy and safety of romosozumab in men with osteoporosis","volume":"103","author":"Lewiecki EM","year":"2018","unstructured":"Lewiecki EM, Blicharski T, Goemaere S, et al.. A phase III randomized placebo-controlled trial to evaluate efficacy and safety of romosozumab in men with osteoporosis. J Clin Endocrinol Metab. 2018, 103:3183-93. 10.1210\/jc.2017-02163","journal-title":"J Clin Endocrinol Metab"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1708322","article-title":"Romosozumab or alendronate for fracture prevention in women with osteoporosis","volume":"377","author":"Saag KG","year":"2017","unstructured":"Saag KG, Petersen J, Brandi ML, et al.. Romosozumab or alendronate for fracture prevention in women with osteoporosis. N Engl J Med. 2017, 377:1417-27. 10.1056\/NEJMoa1708322","journal-title":"N Engl J Med"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-020-00652-w","article-title":"Romosozumab: a review of efficacy, safety, and cardiovascular risk","volume":"19","author":"Fixen C","year":"2021","unstructured":"Fixen C, Tunoa J. Romosozumab: a review of efficacy, safety, and cardiovascular risk. Curr Osteoporos Rep. 2021, 19:15-22. 10.1007\/s11914-020-00652-w","journal-title":"Curr Osteoporos Rep"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/439530-osteoporosis-in-patients-with-marfan-syndrome-a-narrative-review-of-bone-health-and-management","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T06:56:43Z","timestamp":1765695403000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/439530-osteoporosis-in-patients-with-marfan-syndrome-a-narrative-review-of-bone-health-and-management"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,13]]},"references-count":44,"URL":"https:\/\/doi.org\/10.7759\/cureus.99172","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,13]]}}}