{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T02:40:26Z","timestamp":1765766426478,"version":"3.48.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,14]]},"DOI":"10.7759\/cureus.99223","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T02:35:23Z","timestamp":1765766123000},"source":"Crossref","is-referenced-by-count":0,"title":["Gamma Knife-Mimicking Radiosurgery With Cyberknife: A Comparison of Dose Prescription Methodologies for the Treatment of Trigeminal Neuralgia"],"prefix":"10.7759","author":[{"given":"Olivier","family":"Blasi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishna","family":"Monroe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chase","family":"Mallory","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald","family":"Hammers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Monroe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3171\/2017.9.JNS17545","article-title":"Stereotactic radiosurgery for trigeminal neuralgia: a systematic review","volume":"130","author":"Tuleasca C","year":"2018","unstructured":"Tuleasca C, R\u00e9gis J, Sahgal A, et al.. Stereotactic radiosurgery for trigeminal neuralgia: a systematic review. J Neurosurg. 2018, 130:733-57. 10.3171\/2017.9.JNS17545","journal-title":"J Neurosurg"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3171\/2009.7.JNS09694","article-title":"Gamma Knife stereotactic radiosurgery for idiopathic trigeminal neuralgia","volume":"112","author":"Kondziolka D","year":"2010","unstructured":"Kondziolka D, Zorro O, Lobato-Polo J, Kano H, Flannery TJ, Flickinger JC, Lunsford LD. Gamma Knife stereotactic radiosurgery for idiopathic trigeminal neuralgia. J Neurosurg. 2010, 112:758-65. 10.3171\/2009.7.JNS09694","journal-title":"J Neurosurg"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3171\/2022.8.FOCUS22370","article-title":"CyberKnife radiosurgery for trigeminal neuralgia: a retrospective review of 168 cases","volume":"53","author":"Guillemette A","year":"2022","unstructured":"Guillemette A, Heymann S, Roberge D, M\u00e9nard C, Fournier-Gosselin MP. CyberKnife radiosurgery for trigeminal neuralgia: a retrospective review of 168 cases. Neurosurg Focus. 2022, 53:E4. 10.3171\/2022.8.FOCUS22370","journal-title":"Neurosurg Focus"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2016.04.013","article-title":"Trigeminal neuralgia treated with stereotactic radiosurgery: the effect of dose escalation on pain control and treatment outcomes","volume":"96","author":"Kotecha R","year":"2016","unstructured":"Kotecha R, Kotecha R, Modugula S, et al.. Trigeminal neuralgia treated with stereotactic radiosurgery: the effect of dose escalation on pain control and treatment outcomes. Int J Radiat Oncol Biol Phys. 2016, 96:142-8. 10.1016\/j.ijrobp.2016.04.013","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s13566-013-0134-3","article-title":"Trigeminal neuralgia treatment outcomes following Gamma Knife radiosurgery with a minimum 3-year follow-up","volume":"3","author":"Karam SD","year":"2014","unstructured":"Karam SD, Tai A, Wooster M, et al.. Trigeminal neuralgia treatment outcomes following Gamma Knife radiosurgery with a minimum 3-year follow-up. J Radiat Oncol. 2014, 3:125-30. 10.1007\/s13566-013-0134-3","journal-title":"J Radiat Oncol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1186\/s13014-020-01535-1","article-title":"Factors affecting outcome in frameless non-isocentric stereotactic radiosurgery for trigeminal neuralgia: a multicentric cohort study","volume":"15","author":"Conti A","year":"2020","unstructured":"Conti A, Acker G, Pontoriero A, et al.. Factors affecting outcome in frameless non-isocentric stereotactic radiosurgery for trigeminal neuralgia: a multicentric cohort study. Radiat Oncol. 2020, 15:115. 10.1186\/s13014-020-01535-1","journal-title":"Radiat Oncol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci9060134","article-title":"Gamma Knife radiosurgery for trigeminal neuralgia: a comparison of dose protocols","volume":"9","author":"Boling W","year":"2019","unstructured":"Boling W, Song M, Shih W, Karlsson B. Gamma Knife radiosurgery for trigeminal neuralgia: a comparison of dose protocols. Brain Sci. 2019, 9:134. 10.3390\/brainsci9060134","journal-title":"Brain Sci"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0000000000001404","article-title":"Long-term outcomes in the treatment of classical trigeminal neuralgia by Gamma Knife radiosurgery: a retrospective study in patients with minimum 2-year follow-up","volume":"79","author":"Mart\u00ednez Moreno NE","year":"2016","unstructured":"Mart\u00ednez Moreno NE, Guti\u00e9rrez-S\u00e1rraga J, Rey-Portol\u00e9s G, Jim\u00e9nez-Huete A, Mart\u00ednez \u00c1lvarez R. Long-term outcomes in the treatment of classical trigeminal neuralgia by Gamma Knife radiosurgery: a retrospective study in patients with minimum 2-year follow-up. Neurosurgery. 2016, 79:879-88. 10.1227\/NEU.0000000000001404","journal-title":"Neurosurgery"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3171\/2015.2.JNS142144","article-title":"Long-term safety and efficacy of Gamma Knife surgery in classical trigeminal neuralgia: a 497-patient historical cohort study","volume":"124","author":"R\u00e9gis J","year":"2016","unstructured":"R\u00e9gis J, Tuleasca C, Resseguier N, Carron R, Donnet A, Gaudart J, Levivier M. Long-term safety and efficacy of Gamma Knife surgery in classical trigeminal neuralgia: a 497-patient historical cohort study. J Neurosurg. 2016, 124:1079-87. 10.3171\/2015.2.JNS142144","journal-title":"J Neurosurg"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.6014","article-title":"CyberKnife radiosurgery for trigeminal neuralgia","volume":"11","author":"Romanelli P","year":"2019","unstructured":"Romanelli P, Conti A, Redaelli I, Martinotti AS, Bergantin A, Bianchi LC, Beltramo G. CyberKnife radiosurgery for trigeminal neuralgia. Cureus. 2019, 11:e6014. 10.7759\/cureus.6014","journal-title":"Cureus"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000340795.87734.70","article-title":"CyberKnife stereotactic radiosurgical rhizotomy for trigeminal neuralgia: anatomic and morphological considerations","volume":"64","author":"Borchers JD 3rd","year":"2009","unstructured":"Borchers JD 3rd, Yang HJ, Sakamoto GT, Howes GA, Gupta G, Chang SD, Adler JR Jr. CyberKnife stereotactic radiosurgical rhizotomy for trigeminal neuralgia: anatomic and morphological considerations. Neurosurgery. 2009, 64:A91-5. 10.1227\/01.NEU.0000340795.87734.70","journal-title":"Neurosurgery"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.nec.2016.02.006","article-title":"Gamma Knife surgery in trigeminal neuralgia","volume":"27","author":"Wolf A","year":"2016","unstructured":"Wolf A, Kondziolka D. Gamma Knife surgery in trigeminal neuralgia. Neurosurg Clin N Am. 2016, 27:297-304. 10.1016\/j.nec.2016.02.006","journal-title":"Neurosurg Clin N Am"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0b013e3182320d36","article-title":"Predictive variables for the successful treatment of trigeminal neuralgia with Gamma Knife radiosurgery","volume":"70","author":"Marshall K","year":"2012","unstructured":"Marshall K, Chan MD, McCoy TP, et al.. Predictive variables for the successful treatment of trigeminal neuralgia with Gamma Knife radiosurgery. Neurosurgery. 2012, 70:566-73. 10.1227\/NEU.0b013e3182320d36","journal-title":"Neurosurgery"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2018.01.088","article-title":"Early stereotactic radiosurgery for medically refractory trigeminal neuralgia","volume":"112","author":"Lee CC","year":"2018","unstructured":"Lee CC, Chen CJ, Chong ST, et al.. Early stereotactic radiosurgery for medically refractory trigeminal neuralgia. World Neurosurg. 2018, 112:e569-75. 10.1016\/j.wneu.2018.01.088","journal-title":"World Neurosurg"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3171\/2021.8.JNS21658","article-title":"Linear accelerator-based radiosurgery for trigeminal neuralgia: comparative outcomes of frame-based and mask-based techniques","volume":"137","author":"Kienzler JC","year":"2022","unstructured":"Kienzler JC, Tenn S, Chivukula S, et al.. Linear accelerator-based radiosurgery for trigeminal neuralgia: comparative outcomes of frame-based and mask-based techniques. J Neurosurg. 2022, 137:217-26. 10.3171\/2021.8.JNS21658","journal-title":"J Neurosurg"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.1362","article-title":"Truebeam radiosurgery for the treatment of trigeminal neuralgia: preliminary results at a single institution","volume":"9","author":"Kerolus MG","year":"2017","unstructured":"Kerolus MG, Sen N, Mayekar S, et al.. Truebeam radiosurgery for the treatment of trigeminal neuralgia: preliminary results at a single institution. Cureus. 2017, 9:e1362. 10.7759\/cureus.1362","journal-title":"Cureus"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-010-0610-0","article-title":"The retrogasserian zone versus dorsal root entry zone: comparison of two targeting techniques of Gamma Knife radiosurgery for trigeminal neuralgia","volume":"152","author":"Park SH","year":"2010","unstructured":"Park SH, Hwang SK, Kang DH, Park J, Hwang JH, Sung JK. The retrogasserian zone versus dorsal root entry zone: comparison of two targeting techniques of Gamma Knife radiosurgery for trigeminal neuralgia. Acta Neurochir (Wien). 2010, 152:1165-70. 10.1007\/s00701-010-0610-0","journal-title":"Acta Neurochir (Wien)"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000341631.49154.62","article-title":"Nonisocentric radiosurgical rhizotomy for trigeminal neuralgia","volume":"64","author":"Adler JR Jr","year":"2009","unstructured":"Adler JR Jr, Bower R, Gupta G, et al.. Nonisocentric radiosurgical rhizotomy for trigeminal neuralgia. Neurosurgery. 2009, 64:A84-90. 10.1227\/01.NEU.0000341631.49154.62","journal-title":"Neurosurgery"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3171\/2011.6.JNS102129","article-title":"CyberKnife radiosurgery for trigeminal neuralgia: unanticipated iatrogenic effect following successful treatment","volume":"115","author":"Peddada AV","year":"2011","unstructured":"Peddada AV, Sceats DJ, White GA, et al.. CyberKnife radiosurgery for trigeminal neuralgia: unanticipated iatrogenic effect following successful treatment. J Neurosurg. 2011, 115:940-4. 10.3171\/2011.6.JNS102129","journal-title":"J Neurosurg"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2022.12.110","article-title":"Long-term results of Gamma Knife radiosurgery for trigeminal neuralgia","volume":"171","author":"Sato D","year":"2023","unstructured":"Sato D, Hayashi M, Horiba A, Horisawa S, Kawamata T. Long-term results of Gamma Knife radiosurgery for trigeminal neuralgia. World Neurosurg. 2023, 171:e787-91. 10.1016\/j.wneu.2022.12.110","journal-title":"World Neurosurg"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3171\/2010.7.GKS10978","article-title":"Gamma Knife surgery for trigeminal neuralgia: a review of 450 consecutive cases","volume":"113","author":"Verheul JB","year":"2010","unstructured":"Verheul JB, Hanssens PE, Lie ST, Leenstra S, Piersma H, Beute GN. Gamma Knife surgery for trigeminal neuralgia: a review of 450 consecutive cases. J Neurosurg. 2010, 113:160-7. 10.3171\/2010.7.GKS10978","journal-title":"J Neurosurg"},{"key":"ref22","article-title":"Trigeminal nerve integrated dose and pain outcome after Gamma Knife radiosurgery for trigeminal neuralgia","volume":"1","author":"Alahmadi H","year":"2012","unstructured":"Alahmadi H, Zadeh G, Laperriere N, Vachhrajani S, Mazloom N, Gentili F, Hodaie M. Trigeminal nerve integrated dose and pain outcome after Gamma Knife radiosurgery for trigeminal neuralgia. J Radiosurg SBRT. 2012, 1:295-301.","journal-title":"J Radiosurg SBRT"},{"key":"ref23","article-title":"Gamma Knife radiosurgery for typical trigeminal neuralgia: an institutional review of 108 patients","volume":"4","author":"Elaimy AL","year":"2013","unstructured":"Elaimy AL, Lamm AF, Demakas JJ, et al.. Gamma Knife radiosurgery for typical trigeminal neuralgia: an institutional review of 108 patients. Surg Neurol Int. 2013, 4:92.","journal-title":"Surg Neurol Int"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.3171\/2016.12.JNS161862","article-title":"The relationship of dose to nerve volume in predicting pain recurrence after stereotactic radiosurgery in trigeminal neuralgia","volume":"128","author":"Wolf A","year":"2018","unstructured":"Wolf A, Tyburczy A, Ye JC, Fatterpekar G, Silverman JS, Kondziolka D. The relationship of dose to nerve volume in predicting pain recurrence after stereotactic radiosurgery in trigeminal neuralgia. J Neurosurg. 2018, 128:891-6. 10.3171\/2016.12.JNS161862","journal-title":"J Neurosurg"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1159\/000075112","article-title":"CyberKnife radiosurgery for trigeminal neuralgia","volume":"81","author":"Romanelli P","year":"2004","unstructured":"Romanelli P, Heit G, Chang SD, Martin D, Pham C, Adler J. CyberKnife radiosurgery for trigeminal neuralgia. Stereotact Funct Neurosurg. 2004, 81:105-9. 10.1159\/000075112","journal-title":"Stereotact Funct Neurosurg"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2017.10.014","article-title":"Outcomes of two-isocenter Gamma Knife radiosurgery for patients with typical trigeminal neuralgia: pain response and quality of life","volume":"109","author":"Zhao H","year":"2018","unstructured":"Zhao H, Shen Y, Yao D, Xiong N, Abdelmaksoud A, Wang H. Outcomes of two-isocenter Gamma Knife radiosurgery for patients with typical trigeminal neuralgia: pain response and quality of life. World Neurosurg. 2018, 109:e531-8. 10.1016\/j.wneu.2017.10.014","journal-title":"World Neurosurg"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01606-6","article-title":"Does increased nerve length within the treatment volume improve trigeminal neuralgia radiosurgery? A prospective double-blind, randomized study","volume":"51","author":"Flickinger JC","year":"2001","unstructured":"Flickinger JC, Pollock BE, Kondziolka D, Phuong LK, Foote RL, Stafford SL, Lunsford LD. Does increased nerve length within the treatment volume improve trigeminal neuralgia radiosurgery? A prospective double-blind, randomized study. Int J Radiat Oncol Biol Phys. 2001, 51:449-54. 10.1016\/S0360-3016(01)01606-6","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.3171\/JNS\/2008\/109\/12\/S28","article-title":"Comparison of the results of 2 targeting methods in Gamma Knife surgery for trigeminal neuralgia","volume":"109","author":"Matsuda S","year":"2008","unstructured":"Matsuda S, Serizawa T, Nagano O, Ono J. Comparison of the results of 2 targeting methods in Gamma Knife surgery for trigeminal neuralgia. J Neurosurg. 2008, 109:185-9. 10.3171\/JNS\/2008\/109\/12\/S28","journal-title":"J Neurosurg"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2020.06.147","article-title":"Gamma Knife radiosurgery for trigeminal neuralgia: role of trigeminal length and pontotrigeminal angle on target definition and on clinical effects","volume":"142","author":"Barzaghi LR","year":"2020","unstructured":"Barzaghi LR, Albano L, Scudieri C, Gigliotti CR, Nadin F, Del Vecchio A, Mortini P. Gamma Knife radiosurgery for trigeminal neuralgia: role of trigeminal length and pontotrigeminal angle on target definition and on clinical effects. World Neurosurg. 2020, 142:e140-50. 10.1016\/j.wneu.2020.06.147","journal-title":"World Neurosurg"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.3171\/2014.7.GKS141432","article-title":"Radiosurgery target location and individual anatomical variation in trigeminal nerves","volume":"121","author":"Hung YC","year":"2014","unstructured":"Hung YC, Lee CC, Liu KD, Chung WY, Pan DH, Yang HC. Radiosurgery target location and individual anatomical variation in trigeminal nerves. J Neurosurg. 2014, 121:203-9. 10.3171\/2014.7.GKS141432","journal-title":"J Neurosurg"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/428701-gamma-knife-mimicking-radiosurgery-with-cyberknife-a-comparison-of-dose-prescription-methodologies-for-the-treatment-of-trigeminal-neuralgia","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T02:35:24Z","timestamp":1765766124000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/428701-gamma-knife-mimicking-radiosurgery-with-cyberknife-a-comparison-of-dose-prescription-methodologies-for-the-treatment-of-trigeminal-neuralgia"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,14]]},"references-count":30,"URL":"https:\/\/doi.org\/10.7759\/cureus.99223","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,14]]}}}