{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T01:25:58Z","timestamp":1788830758905,"version":"build-2803163510"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,15]]},"DOI":"10.7759\/cureus.99312","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T19:18:54Z","timestamp":1765826334000},"source":"Crossref","is-referenced-by-count":1,"title":["Spontaneous Heparin-Induced Thrombocytopenia Following Orthopedic Surgery"],"prefix":"10.7759","author":[{"given":"Aleksey","family":"Korolyov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-11-012450","article-title":"Gender imbalance and risk factor interactions in heparin-induced thrombocytopenia","volume":"108","author":"Warkentin TE","year":"2006","unstructured":"Warkentin TE, Sheppard JA, Sigouin CS, Kohlmann T, Eichler P, Greinacher A. Gender imbalance and risk factor interactions in heparin-induced thrombocytopenia. Blood. 2006, 108:2937-41. 10.1182\/blood-2005-11-012450","journal-title":"Blood"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-04-1546","article-title":"Risk for heparin-induced thrombocytopenia with unfractionated and low-molecular-weight heparin thromboprophylaxis: a meta-analysis","volume":"106","author":"Martel N","year":"2005","unstructured":"Martel N, Lee J, Wells PS. Risk for heparin-induced thrombocytopenia with unfractionated and low-molecular-weight heparin thromboprophylaxis: a meta-analysis. Blood. 2005, 106:2710-5. 10.1182\/blood-2005-04-1546","journal-title":"Blood"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-2109","article-title":"The incidence of recognized heparin-induced thrombocytopenia in a large, tertiary care teaching hospital","volume":"131","author":"Smythe MA","year":"2007","unstructured":"Smythe MA, Koerber JM, Mattson JC. The incidence of recognized heparin-induced thrombocytopenia in a large, tertiary care teaching hospital. Chest. 2007, 131:1644-9. 10.1378\/chest.06-2109","journal-title":"Chest"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2009.03.026","article-title":"Incidence of thrombocytopenia in hospitalized patients with venous thromboembolism","volume":"122","author":"Stein PD","year":"2009","unstructured":"Stein PD, Hull RD, Matta F, Yaekoub AY, Liang J. Incidence of thrombocytopenia in hospitalized patients with venous thromboembolism. Am J Med. 2009, 122:919-30. 10.1016\/j.amjmed.2009.03.026","journal-title":"Am J Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-01-549741","article-title":"Spontaneous heparin-induced thrombocytopenia syndrome: 2 new cases and a proposal for defining this disorder","volume":"123","author":"Warkentin TE","year":"2014","unstructured":"Warkentin TE, Basciano PA, Knopman J, Bernstein RA. Spontaneous heparin-induced thrombocytopenia syndrome: 2 new cases and a proposal for defining this disorder. Blood. 2014, 123:3651-4. 10.1182\/blood-2014-01-549741","journal-title":"Blood"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2008.03040.x","article-title":"Fatal heparin-induced thrombocytopenia (HIT) during warfarin thromboprophylaxis following orthopedic surgery: another example of 'spontaneous' HIT?","volume":"6","author":"Jay RM","year":"2008","unstructured":"Jay RM, Warkentin TE. Fatal heparin-induced thrombocytopenia (HIT) during warfarin thromboprophylaxis following orthopedic surgery: another example of 'spontaneous' HIT?. J Thromb Haemost. 2008, 6:1598-600. 10.1111\/j.1538-7836.2008.03040.x","journal-title":"J Thromb Haemost"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2008.03263.x","article-title":"Heparin-induced thrombocytopenia (HIT) during postoperative warfarin thromboprophylaxis: a second example of postorthopedic surgery 'spontaneous' HIT","volume":"7","author":"Pruthi RK","year":"2009","unstructured":"Pruthi RK, Daniels PR, Nambudiri GS, Warkentin TE. Heparin-induced thrombocytopenia (HIT) during postoperative warfarin thromboprophylaxis: a second example of postorthopedic surgery 'spontaneous' HIT. J Thromb Haemost. 2009, 7:499-501. 10.1111\/j.1538-7836.2008.03263.x","journal-title":"J Thromb Haemost"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1160\/TH12-11-0865","article-title":"Adrenal haemorrhage due to heparin-induced thrombocytopenia","volume":"109","author":"Ketha S","year":"2013","unstructured":"Ketha S, Smithedajkul P, Vella A, Pruthi R, Wysokinski W, McBane R. Adrenal haemorrhage due to heparin-induced thrombocytopenia. Thromb Haemost. 2013, 109:669-75. 10.1160\/TH12-11-0865","journal-title":"Thromb Haemost"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/343296-spontaneous-heparin-induced-thrombocytopenia-following-orthopedic-surgery","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T19:18:55Z","timestamp":1765826335000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/343296-spontaneous-heparin-induced-thrombocytopenia-following-orthopedic-surgery"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,15]]},"references-count":8,"URL":"https:\/\/doi.org\/10.7759\/cureus.99312","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,15]]}}}