{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T11:45:16Z","timestamp":1788090316553,"version":"build-2803163510"},"reference-count":12,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,18]]},"DOI":"10.7759\/cureus.99540","type":"journal-article","created":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T14:34:36Z","timestamp":1766068476000},"source":"Crossref","is-referenced-by-count":1,"title":["Efavirenz-Induced Hepatitis Mimicking Autoimmune Hepatitis: A Case Report"],"prefix":"10.7759","author":[{"given":"Adibul H","family":"Chowdhury","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dristy","family":"Chowdhury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Israt","family":"Jahan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adaze","family":"Woghiren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Saleh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.70174","article-title":"Deciphering the molecular mechanisms of HAART-induced hepatotoxicity","volume":"39","author":"Ezhilarasan D","year":"2025","unstructured":"Ezhilarasan D, Karthick M, Sharmila M, Sanjay S, Mani U. Deciphering the molecular mechanisms of HAART-induced hepatotoxicity. J Biochem Mol Toxicol. 2025, 39:e70174. 10.1002\/jbt.70174","journal-title":"J Biochem Mol Toxicol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0027810","article-title":"Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients","volume":"6","author":"Yimer G","year":"2011","unstructured":"Yimer G, Ueda N, Habtewold A, et al.. Pharmacogenetic &amp; pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients. PLoS One. 2011, 6:e27810. 10.1371\/journal.pone.0027810","journal-title":"PLoS One"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3390\/cells10071687","article-title":"NNRTI and liver damage: evidence of their association and the mechanisms involved","volume":"10","author":"Benedicto AM","year":"2021","unstructured":"Benedicto AM, Fuster-Mart\u00ednez I, Tosca J, Esplugues JV, Blas-Garc\u00eda A, Apostolova N. NNRTI and liver damage: evidence of their association and the mechanisms involved. Cells. 2021, 10:1687. 10.3390\/cells10071687","journal-title":"Cells"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0040180","article-title":"Liver enzyme abnormalities and associated risk factors in HIV patients on efavirenz-based HAART with or without tuberculosis co-infection in Tanzania","volume":"7","author":"Mugusi S","year":"2012","unstructured":"Mugusi S, Ngaimisi E, Janabi M, et al.. Liver enzyme abnormalities and associated risk factors in HIV patients on efavirenz-based HAART with or without tuberculosis co-infection in Tanzania. PLoS One. 2012, 7:e40180. 10.1371\/journal.pone.0040180","journal-title":"PLoS One"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0094271","article-title":"Evaluation of patterns of liver toxicity in patients on antiretroviral and anti-tuberculosis drugs: a prospective four arm observational study in ethiopian patients","volume":"9","author":"Yimer G","year":"2014","unstructured":"Yimer G, Gry M, Amogne W, et al.. Evaluation of patterns of liver toxicity in patients on antiretroviral and anti-tuberculosis drugs: a prospective four arm observational study in ethiopian patients. PLoS One. 2014, 9:e94271. 10.1371\/journal.pone.0094271","journal-title":"PLoS One"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/1270716","article-title":"Acute liver failure among patients on efavirenz-based antiretroviral therapy","volume":"2018","author":"Segamwenge IL","year":"2018","unstructured":"Segamwenge IL, Bernard MK. Acute liver failure among patients on efavirenz-based antiretroviral therapy. Case Rep Hepatol. 2018, 2018:1270716. 10.1155\/2018\/1270716","journal-title":"Case Rep Hepatol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/tpj.2011.34","article-title":"High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of na\u00efve HIV patients from Ethiopia: a prospective cohort study","volume":"12","author":"Yimer G","year":"2012","unstructured":"Yimer G, Amogne W, Habtewold A, et al.. High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of na\u00efve HIV patients from Ethiopia: a prospective cohort study. Pharmacogenomics J. 2012, 12:499-506. 10.1038\/tpj.2011.34","journal-title":"Pharmacogenomics J"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2010.08.024","article-title":"Liver disease in the HIV-infected individual","volume":"8","author":"Price JC","year":"2010","unstructured":"Price JC, Thio CL. Liver disease in the HIV-infected individual. Clin Gastroenterol Hepatol. 2010, 8:1002-12. 10.1016\/j.cgh.2010.08.024","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/pds.5883","article-title":"Liver injury in people with HIV on antituberculosis and\/or antiretroviral therapy-assessing causality using the updated Roussel Uclaf Causality assessment method","volume":"33","author":"Gunter HM","year":"2024","unstructured":"Gunter HM, Tatz G, Maartens G, Spearman CW, Mehta U, Cohen K. Liver injury in people with HIV on antituberculosis and\/or antiretroviral therapy-assessing causality using the updated Roussel Uclaf Causality assessment method. Pharmacoepidemiol Drug Saf. 2024, 33:e5883. 10.1002\/pds.5883","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/jia2.25444","article-title":"Liver function test abnormalities in a longitudinal cohort of Thai individuals treated since acute HIV infection","volume":"23","author":"Peluso MJ","year":"2020","unstructured":"Peluso MJ, Colby DJ, Pinyakorn S, et al.. Liver function test abnormalities in a longitudinal cohort of Thai individuals treated since acute HIV infection. J Int AIDS Soc. 2020, 23:e25444. 10.1002\/jia2.25444","journal-title":"J Int AIDS Soc"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/0168-8278(95)80226-6","article-title":"Histological grading and staging of chronic hepatitis","volume":"22","author":"Ishak K","year":"1995","unstructured":"Ishak K, Baptista A, Bianchi L, et al.. Histological grading and staging of chronic hepatitis. J Hepatol. 1995, 22:696-9. 10.1016\/0168-8278(95)80226-6","journal-title":"J Hepatol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(93)90101-6","article-title":"Causality assessment of adverse reactions to drugs: I. A novel method based on the conclusions of international consensus meetings","volume":"46","author":"Danan G","year":"1993","unstructured":"Danan G, Benichou C. Causality assessment of adverse reactions to drugs: I. A novel method based on the conclusions of international consensus meetings. J Clin Epidemiol. 1993, 46:1323-30.. 10.1016\/0895-4356(93)90101-6","journal-title":"J Clin Epidemiol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/429796-efavirenz-induced-hepatitis-mimicking-autoimmune-hepatitis-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T14:34:36Z","timestamp":1766068476000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/429796-efavirenz-induced-hepatitis-mimicking-autoimmune-hepatitis-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,18]]},"references-count":12,"URL":"https:\/\/doi.org\/10.7759\/cureus.99540","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,18]]}}}