{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T09:00:54Z","timestamp":1766134854783,"version":"3.48.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,19]]},"DOI":"10.7759\/cureus.99594","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T08:57:38Z","timestamp":1766134658000},"source":"Crossref","is-referenced-by-count":0,"title":["Serial C-reactive Protein as a Sensitive Marker of Treatment Response and Disease Severity in Acute Hand Infections"],"prefix":"10.7759","author":[{"given":"Sunandan","family":"Datta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bratati","family":"Bandyopadhyay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lydia  S","family":"Abraham","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul H","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Al-Jaafar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pelumi","family":"Tawose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manula","family":"Wijewardene","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1054\/cuor.2002.0318","article-title":"Hand infections","volume":"17","author":"Belcher HJC","year":"2003","unstructured":"Belcher HJC, Clare TD. Hand infections. Curr Orthop. 2003, 17:28-43. 10.1054\/cuor.2002.0318","journal-title":"Curr Orthop"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hcl.2020.03.001","article-title":"Hand infections: epidemiology and public health burden","volume":"36","author":"Gundlach BK","year":"2020","unstructured":"Gundlach BK, Sasor SE, Chung KC. Hand infections: epidemiology and public health burden. Hand Clin. 2020, 36:275-83. 10.1016\/j.hcl.2020.03.001","journal-title":"Hand Clin"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1308\/rcsbull.2021.126","article-title":"DIY injuries","volume":"103","author":"Winter G","year":"2021","unstructured":"Winter G. DIY injuries. Bull R Coll Surg Engl. 2021, 103:10.1308\/rcsbull.2021.126","journal-title":"Bull R Coll Surg Engl"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1302\/2633-1462.15.BJO-2020-0028.R1","article-title":"The effects of a UK lockdown on orthopaedic trauma admissions and surgical cases: a multicentre comparative study","volume":"1","author":"Hampton M","year":"2020","unstructured":"Hampton M, Clark M, Baxter I, Stevens R, Flatt E, Murray J, Wembridge K. The effects of a UK lockdown on orthopaedic trauma admissions and surgical cases: a multicentre comparative study. Bone Jt Open. 2020, 1:137-43. 10.1302\/2633-1462.15.BJO-2020-0028.R1","journal-title":"Bone Jt Open"},{"key":"ref5","article-title":"Hand infection","author":"Moran TE","year":"2023","unstructured":"Moran TE, Freilich AM. Hand infection. StatPearls [Internet]. StatPearls Publishing, Treasure Island (FL); 2023."},{"key":"ref6","article-title":"Acute hand infections","volume":"99","author":"Rerucha CM","year":"2019","unstructured":"Rerucha CM, Ewing JT, Oppenlander KE, Cowan WC. Acute hand infections. Am Fam Physician. 2019, 99:228-36.","journal-title":"Am Fam Physician"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1177\/1558944717750921","article-title":"MRSA incidence and antibiotic trends in urban hand infections: a 10-year longitudinal study","volume":"14","author":"Kistler JM","year":"2019","unstructured":"Kistler JM, Thoder JJ, Ilyas AM. MRSA incidence and antibiotic trends in urban hand infections: a 10-year longitudinal study. Hand (N Y). 2019, 14:449-54. 10.1177\/1558944717750921","journal-title":"Hand (N Y)"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1148\/rg.347130101","article-title":"Hand infections: anatomy, types and spread of infection, imaging findings, and treatment options","volume":"34","author":"Patel DB","year":"2014","unstructured":"Patel DB, Emmanuel NB, Stevanovic MV, Matcuk GR Jr, Gottsegen CJ, Forrester DM, White EA. Hand infections: anatomy, types and spread of infection, imaging findings, and treatment options. Radiographics. 2014, 34:1968-86. 10.1148\/rg.347130101","journal-title":"Radiographics"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.cps.2019.03.003","article-title":"Hand infections","volume":"46","author":"Teo WZ","year":"2019","unstructured":"Teo WZ, Chung KC. Hand infections. Clin Plast Surg. 2019, 46:371-81. 10.1016\/j.cps.2019.03.003","journal-title":"Clin Plast Surg"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2011.05.035","article-title":"Hand infections","volume":"36","author":"McDonald LS","year":"2011","unstructured":"McDonald LS, Bavaro MF, Hofmeister EP, Kroonen LT. Hand infections. J Hand Surg Am. 2011, 36:1403-12. 10.1016\/j.jhsa.2011.05.035","journal-title":"J Hand Surg Am"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhsa.2013.08.094","article-title":"The diagnostic accuracy of inflammatory blood markers for purulent flexor tenosynovitis","volume":"38","author":"Bishop GB","year":"2013","unstructured":"Bishop GB, Born T, Kakar S, Jawa A. The diagnostic accuracy of inflammatory blood markers for purulent flexor tenosynovitis. J Hand Surg Am. 2013, 38:2208-11. 10.1016\/j.jhsa.2013.08.094","journal-title":"J Hand Surg Am"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.5194\/jbji-8-119-2023","article-title":"Evaluating the utility of inflammatory markers in the diagnosis of soft tissue abscesses of the forearm and hand","volume":"8","author":"Blumenthal SR","year":"2023","unstructured":"Blumenthal SR, Cheema AN, Zhang SE, Gray BL, Kazmers NH. Evaluating the utility of inflammatory markers in the diagnosis of soft tissue abscesses of the forearm and hand. J Bone Jt Infect. 2023, 8:119-23. 10.5194\/jbji-8-119-2023","journal-title":"J Bone Jt Infect"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1177\/1558944719873147","article-title":"Acute-phase reactants in operatively treated upper extremity infections: a retrospective review","volume":"16","author":"Gauger EM","year":"2021","unstructured":"Gauger EM, Mitchell PM, Halverson SJ, O'Neill DE, Reasoner K, Desai MJ, Lee DH. Acute-phase reactants in operatively treated upper extremity infections: a retrospective review. Hand (N Y). 2021, 16:546-50. 10.1177\/1558944719873147","journal-title":"Hand (N Y)"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2005.06.009","article-title":"Epidemiology of bacterial hand infections","volume":"10","author":"Houshian S","year":"2006","unstructured":"Houshian S, Seyedipour S, Wedderkopp N. Epidemiology of bacterial hand infections. Int J Infect Dis. 2006, 10:315-19. 10.1016\/j.ijid.2005.06.009","journal-title":"Int J Infect Dis"},{"key":"ref15","article-title":"Comparative Value of Erythrocyte Sedimentation Rate (ESR) and C-Reactive Protein (CRP) Testing in Combination Versus Individually for the Diagnosis of Undifferentiated Patients With Suspected Inflammatory Disease or Serious Infection: A Systematic Review and Economic Analysis","author":"Assasi N","year":"2015","unstructured":"Assasi N, Blackhouse G, Campbell K, et al.. Comparative Value of Erythrocyte Sedimentation Rate (ESR) and C-Reactive Protein (CRP) Testing in Combination Versus Individually for the Diagnosis of Undifferentiated Patients With Suspected Inflammatory Disease or Serious Infection: A Systematic Review and Economic Analysis. Canadian Agency for Drugs and Technologies in Health, Ottawa (ON); 2015."},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofv098","article-title":"Acute phase reactants in infections: evidence-based review and a guide for clinicians","volume":"2","author":"Markanday A","year":"2015","unstructured":"Markanday A. Acute phase reactants in infections: evidence-based review and a guide for clinicians. Open Forum Infect Dis. 2015, 2:ofv098. 10.1093\/ofid\/ofv098","journal-title":"Open Forum Infect Dis"},{"key":"ref17","doi-asserted-by":"crossref","DOI":"10.1016\/S0030-5898(20)31724-7","article-title":"Hand infections","volume":"23","author":"Hausman MR","year":"1992","unstructured":"Hausman MR, Lisser SP. Hand infections. Orthop Clin North Am. 1992, 23:171-85.","journal-title":"Orthop Clin North Am"},{"key":"ref18","article-title":"Acute and chronic paronychia","volume":"96","author":"Leggit JC","year":"2017","unstructured":"Leggit JC. Acute and chronic paronychia. Am Fam Physician. 2017, 96:44-51.","journal-title":"Am Fam Physician"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1302\/2058-5241.4.180082","article-title":"Infections of the hand: an overview","volume":"4","author":"Flevas DA","year":"2019","unstructured":"Flevas DA, Syngouna S, Fandridis E, Tsiodras S, Mavrogenis AF. Infections of the hand: an overview. EFORT Open Rev. 2019, 4:183-93. 10.1302\/2058-5241.4.180082","journal-title":"EFORT Open Rev"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms8060838","article-title":"Infections of deep hand and wrist compartments","volume":"8","author":"Malizos KN","year":"2020","unstructured":"Malizos KN, Papadopoulou ZK, Ziogkou AN, Rigopoulos N, Athanaselis ED, Varitimidis SE, Dailiana ZC. Infections of deep hand and wrist compartments. Microorganisms. 2020, 8:838. 10.3390\/microorganisms8060838","journal-title":"Microorganisms"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12632","article-title":"Pan-European early switch\/early discharge opportunities exist for hospitalized patients with methicillin-resistant Staphylococcus aureus complicated skin and soft tissue infections","volume":"20","author":"Nathwani D","year":"2014","unstructured":"Nathwani D, Eckmann C, Lawson W, et al.. Pan-European early switch\/early discharge opportunities exist for hospitalized patients with methicillin-resistant Staphylococcus aureus complicated skin and soft tissue infections. Clin Microbiol Infect. 2014, 20:993-1000. 10.1111\/1469-0691.12632","journal-title":"Clin Microbiol Infect"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijantimicag.2014.04.007","article-title":"Antibiotic treatment patterns across Europe in patients with complicated skin and soft-tissue infections due to meticillin-resistant Staphylococcus aureus: a plea for implementation of early switch and early discharge criteria","volume":"44","author":"Eckmann C","year":"2014","unstructured":"Eckmann C, Lawson W, Nathwani D, et al.. Antibiotic treatment patterns across Europe in patients with complicated skin and soft-tissue infections due to meticillin-resistant Staphylococcus aureus: a plea for implementation of early switch and early discharge criteria. Int J Antimicrob Agents. 2014, 44:56-64. 10.1016\/j.ijantimicag.2014.04.007","journal-title":"Int J Antimicrob Agents"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/446383-serial-c-reactive-protein-as-a-sensitive-marker-of-treatment-response-and-disease-severity-in-acute-hand-infections","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T08:57:39Z","timestamp":1766134659000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/446383-serial-c-reactive-protein-as-a-sensitive-marker-of-treatment-response-and-disease-severity-in-acute-hand-infections"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,19]]},"references-count":22,"URL":"https:\/\/doi.org\/10.7759\/cureus.99594","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,19]]}}}