{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,21]],"date-time":"2025-12-21T04:50:18Z","timestamp":1766292618176,"version":"3.48.0"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,20]]},"DOI":"10.7759\/cureus.99738","type":"journal-article","created":{"date-parts":[[2025,12,21]],"date-time":"2025-12-21T04:48:21Z","timestamp":1766292501000},"source":"Crossref","is-referenced-by-count":0,"title":["A Durable Response in Sinonasal Undifferentiated Carcinoma Treated With Subtotal Resection and Ultra-Early Postoperative Chemoradiotherapy: A Case Report"],"prefix":"10.7759","author":[{"given":"Kota","family":"Hiraoka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shingo","family":"Umemoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaori","family":"Tateyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Hirano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","article-title":"Sinonasal undifferentiated carcinoma: an aggressive neoplasm derived from schneiderian epithelium and distinct from olfactory neuroblastoma","volume":"10","author":"Frierson Jr HF","year":"1986","unstructured":"Frierson Jr HF, Mills SE, Fechner RE, Taxy JB, Levine PA. Sinonasal undifferentiated carcinoma: an aggressive neoplasm derived from schneiderian epithelium and distinct from olfactory neuroblastoma. Am J Surg Pathol. 1986, 10:771-9.","journal-title":"Am J Surg Pathol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1186\/1916-0216-42-2","article-title":"Sinonasal undifferentiated carcinoma (SNUC): the Alberta experience and literature review","volume":"42","author":"Xu CC","year":"2013","unstructured":"Xu CC, Dziegielewski PT, McGaw WT, Seikaly H. Sinonasal undifferentiated carcinoma (SNUC): the Alberta experience and literature review. J Otolaryngol Head Neck Surg. 2013, 42:10.1186\/1916-0216-42-2","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2023.03.033","article-title":"The SINTART 1 study. A phase II non-randomised controlled trial of induction chemotherapy, surgery, photon-, proton-\u00a0and carbon ion-based radiotherapy integration in patients with locally advanced resectable sinonasal tumours","volume":"187","author":"Resteghini C","year":"2023","unstructured":"Resteghini C, Castelnuovo P, Nicolai P, et al.. The SINTART 1 study. A phase II non-randomised controlled trial of induction chemotherapy, surgery, photon-, proton-\u00a0and carbon ion-based radiotherapy integration in patients with locally advanced resectable sinonasal tumours. Eur J Cancer. 2023, 187:185-94. 10.1016\/j.ejca.2023.03.033","journal-title":"Eur J Cancer"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2013.06.005","article-title":"Improved clinical outcomes with multi-modality therapy for sinonasal undifferentiated carcinoma of the head and neck","volume":"34","author":"Yoshida E","year":"2013","unstructured":"Yoshida E, Aouad R, Fragoso R, Farwell DG, Gandour-Edwards R, Donald PJ, Chen AM. Improved clinical outcomes with multi-modality therapy for sinonasal undifferentiated carcinoma of the head and neck. Am J Otolaryngol. 2013, 34:658-63. 10.1016\/j.amjoto.2013.06.005","journal-title":"Am J Otolaryngol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2013.10.001","article-title":"Radiotherapy for sinonasal undifferentiated carcinoma","volume":"35","author":"Christopherson K","year":"2014","unstructured":"Christopherson K, Werning JW, Malyapa RS, Morris CG, Mendenhall WM. Radiotherapy for sinonasal undifferentiated carcinoma. Am J Otolaryngol. 2014, 35:141-6. 10.1016\/j.amjoto.2013.10.001","journal-title":"Am J Otolaryngol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2007.06.057","article-title":"Patterns of failure after combined-modality approaches incorporating radiotherapy for sinonasal undifferentiated carcinoma of the head and neck","volume":"70","author":"Chen AM","year":"2008","unstructured":"Chen AM, Daly ME, El-Sayed I, Garcia J, Lee NY, Bucci MK, Kaplan MJ. Patterns of failure after combined-modality approaches incorporating radiotherapy for sinonasal undifferentiated carcinoma of the head and neck. Int J Radiat Oncol Biol Phys. 2008, 70:338-43. 10.1016\/j.ijrobp.2007.06.057","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-019-0776-4","article-title":"Sinonasal undifferentiated carcinoma","volume":"21","author":"Abdelmeguid AS","year":"2019","unstructured":"Abdelmeguid AS, Bell D, Hanna EY. Sinonasal undifferentiated carcinoma. Curr Oncol Rep. 2019, 21:10.1007\/s11912-019-0776-4","journal-title":"Curr Oncol Rep"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13102364","article-title":"Radiooncological view on therapy outcome after multidisciplinary treatment of sinonasal tumors","volume":"13","author":"Klymenko O","year":"2021","unstructured":"Klymenko O, Buchberger AM, Wollenberg B, et al.. Radiooncological view on therapy outcome after multidisciplinary treatment of sinonasal tumors. Cancers (Basel). 2021, 13:10.3390\/cancers13102364","journal-title":"Cancers (Basel)"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-24-4085","article-title":"Neoadjuvant chemotherapy and surgery versus surgery for organ preservation of T3 and T4a nasal and paranasal sinus squamous cell carcinoma: ECOG-ACRIN EA3163","volume":"31","author":"Saba NF","year":"2025","unstructured":"Saba NF, Flamand Y, Lin DT, et al.. Neoadjuvant chemotherapy and surgery versus surgery for organ preservation of T3 and T4a nasal and paranasal sinus squamous cell carcinoma: ECOG-ACRIN EA3163. Clin Cancer Res. 2025, 31:2339-46. 10.1158\/1078-0432.CCR-24-4085","journal-title":"Clin Cancer Res"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16112085","article-title":"Current status and future directions of proton therapy for head and neck carcinoma","volume":"16","author":"Lillo S","year":"2024","unstructured":"Lillo S, Mirandola A, Vai A, et al.. Current status and future directions of proton therapy for head and neck carcinoma. Cancers (Basel). 2024, 16:10.3390\/cancers16112085","journal-title":"Cancers (Basel)"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.85170","article-title":"Successful management of advanced sinonasal undifferentiated carcinoma using concurrent chemoradiotherapy with simultaneous integrated boost and intensity-modulated radiation therapy: a case report","volume":"17","author":"Kono S","year":"2025","unstructured":"Kono S, Ando R, Nakamizo M, Nagashima Y, Hashimoto Y. Successful management of advanced sinonasal undifferentiated carcinoma using concurrent chemoradiotherapy with simultaneous integrated boost and intensity-modulated radiation therapy: a case report. Cureus. 2025, 17:10.7759\/cureus.85170","journal-title":"Cureus"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djy133","article-title":"Cisplatin every 3 weeks versus weekly with definitive concurrent radiotherapy for squamous cell carcinoma of the head and neck","volume":"111","author":"Bauml JM","year":"2019","unstructured":"Bauml JM, Vinnakota R, Park YH, et al.. Cisplatin every 3 weeks versus weekly with definitive concurrent radiotherapy for squamous cell carcinoma of the head and neck. J Natl Cancer Inst. 2019, 111:490-7. 10.1093\/jnci\/djy133","journal-title":"J Natl Cancer Inst"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2019.00086","article-title":"Low-dose vs. high-dose cisplatin: lessons learned from 59 chemoradiotherapy trials in head and neck cancer","volume":"9","author":"Szturz P","year":"2019","unstructured":"Szturz P, Wouters K, Kiyota N, et al.. Low-dose vs. high-dose cisplatin: lessons learned from 59 chemoradiotherapy trials in head and neck cancer. Front Oncol. 2019, 9:10.3389\/fonc.2019.00086","journal-title":"Front Oncol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/hed.27910","article-title":"Contemporary treatment and outcome of sinonasal undifferentiated carcinoma: a meta-analysis","volume":"46","author":"Burggraf M","year":"2024","unstructured":"Burggraf M, Schiele S, Th\u00f6lken R, L\u00f3pez FJ, Elawany N, Zenk J, Doescher J. Contemporary treatment and outcome of sinonasal undifferentiated carcinoma: a meta-analysis. Head Neck. 2024, 46:2890-900. 10.1002\/hed.27910","journal-title":"Head Neck"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1055\/a-1871-3586","article-title":"Sinonasal undifferentiated carcinoma with failed response to induction chemotherapy","volume":"83","author":"Papazian MR","year":"2022","unstructured":"Papazian MR, Gordon AJ, Chow M, Patel A, Pacione D, Lieberman S, Givi B. Sinonasal undifferentiated carcinoma with failed response to induction chemotherapy. J Neurol Surg Rep. 2022, 83:83-6. 10.1055\/a-1871-3586","journal-title":"J Neurol Surg Rep"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-024-01566-x","article-title":"Nasal cavity and paranasal sinus cancer: diagnosis and treatment","volume":"26","author":"Jakimovska F","year":"2024","unstructured":"Jakimovska F, Stojkovski I, Kjosevska E. Nasal cavity and paranasal sinus cancer: diagnosis and treatment. Curr Oncol Rep. 2024, 26:1057-69. 10.1007\/s11912-024-01566-x","journal-title":"Curr Oncol Rep"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.tranon.2024.101943","article-title":"Targeting sinonasal undifferentiated carcinoma with a combinatory immunotherapy approach","volume":"44","author":"Hoke AT","year":"2024","unstructured":"Hoke AT, Takahashi Y, Padget MR, et al.. Targeting sinonasal undifferentiated carcinoma with a combinatory immunotherapy approach. Transl Oncol. 2024, 44:10.1016\/j.tranon.2024.101943","journal-title":"Transl Oncol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.14338\/IJPT-20-00068.1","article-title":"Long-term outcomes from proton therapy for sinonasal cancers","volume":"8","author":"Dagan R","year":"2021","unstructured":"Dagan R, Uezono H, Bryant C, Holtzman AL, Morris CG, Mendenhall WM. Long-term outcomes from proton therapy for sinonasal cancers. Int J Part Ther. 2021, 8:200-12. 10.14338\/IJPT-20-00068.1","journal-title":"Int J Part Ther"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/448616-a-durable-response-in-sinonasal-undifferentiated-carcinoma-treated-with-subtotal-resection-and-ultra-early-postoperative-chemoradiotherapy-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,21]],"date-time":"2025-12-21T04:48:25Z","timestamp":1766292505000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/448616-a-durable-response-in-sinonasal-undifferentiated-carcinoma-treated-with-subtotal-resection-and-ultra-early-postoperative-chemoradiotherapy-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,20]]},"references-count":18,"URL":"https:\/\/doi.org\/10.7759\/cureus.99738","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,20]]}}}