{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T15:15:34Z","timestamp":1766502934611,"version":"3.48.0"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,23]]},"DOI":"10.7759\/cureus.99925","type":"journal-article","created":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T13:50:18Z","timestamp":1766497818000},"source":"Crossref","is-referenced-by-count":0,"title":["A Rare Case of Non-cirrhotic Hepatocellular Carcinoma in a Female Adolescent: Diagnostic and Multimodal Treatment Challenges in a Low-Resource Setting"],"prefix":"10.7759","author":[{"given":"Yatrasana","family":"Singh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barry","family":"Raghunanan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravi","family":"Maharaj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","article-title":"Cancer Epidemiology in Older Adolescents and Young Adults 15 to 29 Years of Age, Including SEER Incidence and Survival: 1975-2000. National Cancer Institute, NIH Pub. No. 06-5767","author":"Bleyer A","year":"2006","unstructured":"Bleyer A, O\u2019Leary M, Barr R, Ries LA (eds). Cancer Epidemiology in Older Adolescents and Young Adults 15 to 29 Years of Age, Including SEER Incidence and Survival: 1975-2000. National Cancer Institute, NIH Pub. No. 06-5767. National Cancer Institute, Bethesda, MD; 2006."},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.27475","article-title":"Is hepatocellular carcinoma the same disease in children and adults? Comparison of histology, molecular background, and treatment in pediatric and adult patients","volume":"66","author":"Weeda VB","year":"2019","unstructured":"Weeda VB, Aronson DC, Verheij J, Lamers WH. Is hepatocellular carcinoma the same disease in children and adults? Comparison of histology, molecular background, and treatment in pediatric and adult patients. Pediatr Blood Cancer. 2019, 66:e27475. 10.1002\/pbc.27475","journal-title":"Pediatr Blood Cancer"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11292","article-title":"Fibrolamellar hepatocellular carcinoma in children and adolescents","volume":"97","author":"Katzenstein HM","year":"2003","unstructured":"Katzenstein HM, Krailo MD, Malogolowkin MH, et al.. Fibrolamellar hepatocellular carcinoma in children and adolescents. Cancer. 2003, 97:2006-12. 10.1002\/cncr.11292","journal-title":"Cancer"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2013.05.007","article-title":"Hepatocellular carcinoma in children: epidemiology and the impact of regional lymphadenectomy on surgical outcomes","volume":"48","author":"McAteer JP","year":"2013","unstructured":"McAteer JP, Goldin AB, Healey PJ, Gow KW. Hepatocellular carcinoma in children: epidemiology and the impact of regional lymphadenectomy on surgical outcomes. J Pediatr Surg. 2013, 48:2194-201. 10.1016\/j.jpedsurg.2013.05.007","journal-title":"J Pediatr Surg"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i37.10573","article-title":"Biomarkers for the early diagnosis of hepatocellular carcinoma","volume":"21","author":"Tsuchiya N","year":"2015","unstructured":"Tsuchiya N, Sawada Y, Endo I, Saito K, Uemura Y, Nakatsura T. Biomarkers for the early diagnosis of hepatocellular carcinoma. World J Gastroenterol. 2015, 21:10573-83. 10.3748\/wjg.v21.i37.10573","journal-title":"World J Gastroenterol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-018-1285-4","article-title":"Rapid decrease of serum alpha-fetoprotein and tumor volume predicts outcome in children with hepatoblastoma treated with neoadjuvant chemotherapy","volume":"23","author":"Nguyen R","year":"2018","unstructured":"Nguyen R, McCarville MB, Sykes A, Mao S, Wu J, Langham MR Jr, Furman WL. Rapid decrease of serum alpha-fetoprotein and tumor volume predicts outcome in children with hepatoblastoma treated with neoadjuvant chemotherapy. Int J Clin Oncol. 2018, 23:900-7. 10.1007\/s10147-018-1285-4","journal-title":"Int J Clin Oncol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.2147\/JHC.S94008","article-title":"Pediatric hepatocellular carcinoma: challenges and solutions","volume":"4","author":"Schmid I","year":"2017","unstructured":"Schmid I, von Schweinitz D. Pediatric hepatocellular carcinoma: challenges and solutions. J Hepatocell Carcinoma. 2017, 4:15-21. 10.2147\/JHC.S94008","journal-title":"J Hepatocell Carcinoma"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-14504-9_12","article-title":"Chemotherapy for childhood hepatoblastoma and hepatocellular carcinoma","author":"Perilongo G","year":"2010","unstructured":"Perilongo G, Morland, Malogolowkin M. Chemotherapy for childhood hepatoblastoma and hepatocellular carcinoma. Paediatric Liver Tumours. Springer, Berlin, Heidelberg; 2010. 153-63. 10.1007\/978-3-642-14504-9_12"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.23295","article-title":"Sorafenib and cisplatin\/doxorubicin (PLADO) in pediatric hepatocellular carcinoma","volume":"58","author":"Schmid I","year":"2012","unstructured":"Schmid I, H\u00e4berle B, Albert MH, et al.. Sorafenib and cisplatin\/doxorubicin (PLADO) in pediatric hepatocellular carcinoma. Pediatr Blood Cancer. 2012, 58:539-44. 10.1002\/pbc.23295","journal-title":"Pediatr Blood Cancer"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.soc.2020.11.006","article-title":"Liver tumors in pediatric patients","volume":"30","author":"Meyers R","year":"2021","unstructured":"Meyers R, Hiyama E, Czauderna P, Tiao GM. Liver tumors in pediatric patients. Surg Oncol Clin N Am. 2021, 30:253-74. 10.1016\/j.soc.2020.11.006","journal-title":"Surg Oncol Clin N Am"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/425242-a-rare-case-of-non-cirrhotic-hepatocellular-carcinoma-in-a-female-adolescent-diagnostic-and-multimodal-treatment-challenges-in-a-low-resource-setting","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T13:50:18Z","timestamp":1766497818000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/425242-a-rare-case-of-non-cirrhotic-hepatocellular-carcinoma-in-a-female-adolescent-diagnostic-and-multimodal-treatment-challenges-in-a-low-resource-setting"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,23]]},"references-count":10,"URL":"https:\/\/doi.org\/10.7759\/cureus.99925","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,23]]}}}