{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T07:40:02Z","timestamp":1766562002824,"version":"3.48.0"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,12,23]]},"DOI":"10.7759\/cureus.99973","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T06:27:35Z","timestamp":1766557655000},"source":"Crossref","is-referenced-by-count":0,"title":["Use of Angiotensin Receptor-Neprilysin Inhibitors (ARNis) in High-Output Heart Failure in a Young Hemodialysis Patient: Synergistic or Cumulative Effect?"],"prefix":"10.7759","author":[{"given":"Sara R","family":"Silva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elsa","family":"Soares","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Nat\u00e1rio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Artur","family":"Gama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Bernardo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-77-2-201","article-title":"Heart failure as a complication of hemodialysis arteriovenous fistula","volume":"77","author":"Ahearn DJ","year":"1972","unstructured":"Ahearn DJ, Maher JF. Heart failure as a complication of hemodialysis arteriovenous fistula. Ann Intern Med. 1972, 77:201-4. 10.7326\/0003-4819-77-2-201","journal-title":"Ann Intern Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfm549","article-title":"The relationship between the flow of arteriovenous fistula and cardiac output in haemodialysis patients","volume":"23","author":"Basile C","year":"2008","unstructured":"Basile C, Lomonte C, Vernaglione L, Casucci F, Antonelli M, Losurdo N. The relationship between the flow of arteriovenous fistula and cardiac output in haemodialysis patients. Nephrol Dial Transplant. 2008, 23:282-7. 10.1093\/ndt\/gfm549","journal-title":"Nephrol Dial Transplant"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1161\/HYP.0000000000000230","article-title":"Hypertension in patients treated with in-center maintenance hemodialysis: current evidence and future opportunities: a scientific statement from the American Heart Association","volume":"80","author":"Bansal N","year":"2023","unstructured":"Bansal N, Artinian NT, Bakris G, et al.. Hypertension in patients treated with in-center maintenance hemodialysis: current evidence and future opportunities: a scientific statement from the American Heart Association. Hypertension. 2023, 80:e112-22. 10.1161\/HYP.0000000000000230","journal-title":"Hypertension"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2022.09.013","article-title":"Managing heart failure in patients on dialysis: state-of-the-art review","volume":"29","author":"Khan MS","year":"2023","unstructured":"Khan MS, Ahmed A, Greene SJ, et al.. Managing heart failure in patients on dialysis: state-of-the-art review. J Card Fail. 2023, 29:87-107. 10.1016\/j.cardfail.2022.09.013","journal-title":"J Card Fail"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1409077","article-title":"Angiotensin-neprilysin inhibition versus enalapril in heart failure","volume":"371","author":"McMurray JJ","year":"2014","unstructured":"McMurray JJ, Packer M, Desai AS, et al.. Angiotensin-neprilysin inhibition versus enalapril in heart failure. N Engl J Med. 2014, 371:993-1004. 10.1056\/NEJMoa1409077","journal-title":"N Engl J Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000003972","article-title":"Efficacy and safety of sacubitril-valsartan in hypertension patients with end-stage kidney disease on maintenance dialysis: a meta-analysis","volume":"43","author":"Nguyen DV","year":"2025","unstructured":"Nguyen DV, Pham GT, Pham SN, Nguyen HT. Efficacy and safety of sacubitril-valsartan in hypertension patients with end-stage kidney disease on maintenance dialysis: a meta-analysis. J Hypertens. 2025, 43:557-67. 10.1097\/HJH.0000000000003972","journal-title":"J Hypertens"},{"key":"ref7","article-title":"Renal and cardiovascular benefits of sacubitril\/valsartan in patients with chronic kidney disease and heart failure","volume":"8","author":"Gohar A","year":"2023","unstructured":"Gohar A, Kovesdy CP, Kalantar-Zadeh K. Renal and cardiovascular benefits of sacubitril\/valsartan in patients with chronic kidney disease and heart failure. Kidney Int Rep. 2023, 8:766-76.","journal-title":"Kidney Int Rep"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ekir.2023.10.008","article-title":"Systematic review of cardiovascular benefits and safety of sacubitril-valsartan in end-stage kidney disease","volume":"9","author":"Charkviani M","year":"2024","unstructured":"Charkviani M, Krisanapan P, Thongprayoon C, Craici IM, Cheungpasitporn W. Systematic review of cardiovascular benefits and safety of sacubitril-valsartan in end-stage kidney disease. Kidney Int Rep. 2024, 9:39-51. 10.1016\/j.ekir.2023.10.008","journal-title":"Kidney Int Rep"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1471","article-title":"Prospective validation of N-terminal pro B-type natriuretic peptide cut-off concentrations for the diagnosis of acute heart failure","volume":"21","author":"Kozhuharov N","year":"2019","unstructured":"Kozhuharov N, Sabti Z, Wussler D, et al.. Prospective validation of N-terminal pro B-type natriuretic peptide cut-off concentrations for the diagnosis of acute heart failure. Eur J Heart Fail. 2019, 21:813-5. 10.1002\/ejhf.1471","journal-title":"Eur J Heart Fail"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.2848","article-title":"Natriuretic peptides: role in the diagnosis and management of heart failure: a scientific statement from the Heart Failure Association of the European Society of Cardiology, Heart Failure Society of America and Japanese Heart Failure Society","volume":"25","author":"Tsutsui H","year":"2023","unstructured":"Tsutsui H, Albert NM, Coats AJ, et al.. Natriuretic peptides: role in the diagnosis and management of heart failure: a scientific statement from the Heart Failure Association of the European Society of Cardiology, Heart Failure Society of America and Japanese Heart Failure Society. Eur J Heart Fail. 2023, 25:616-31. 10.1002\/ejhf.2848","journal-title":"Eur J Heart Fail"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.2115","article-title":"Universal definition and classification of heart failure: a report of the Heart Failure Society of America, Heart Failure Association of the European Society of Cardiology, Japanese Heart Failure Society and Writing Committee of the Universal Definition of Heart Failure: endorsed by the Canadian Heart Failure Society, Heart Failure Association of India, Cardiac Society of Australia and New Zealand, and Chinese Heart Failure Association","volume":"23","author":"Bozkurt B","year":"2021","unstructured":"Bozkurt B, Coats AJ, Tsutsui H, et al.. Universal definition and classification of heart failure: a report of the Heart Failure Society of America, Heart Failure Association of the European Society of Cardiology, Japanese Heart Failure Society and Writing Committee of the Universal Definition of Heart Failure: endorsed by the Canadian Heart Failure Society, Heart Failure Association of India, Cardiac Society of Australia and New Zealand, and Chinese Heart Failure Association. Eur J Heart Fail. 2021, 23:352-80. 10.1002\/ejhf.2115","journal-title":"Eur J Heart Fail"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(21)00072-2","article-title":"Mildly elevated pulmonary artery systolic pressure on echocardiography: bridging the gap in current guidelines","volume":"9","author":"Jankowich M","year":"2021","unstructured":"Jankowich M, Maron BA, Choudhary G. Mildly elevated pulmonary artery systolic pressure on echocardiography: bridging the gap in current guidelines. Lancet Respir Med. 2021, 9:1185-91. 10.1016\/S2213-2600(21)00072-2","journal-title":"Lancet Respir Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.13002","article-title":"Effect of sacubitril\/valsartan on renal function: a systematic review and meta-analysis of randomized controlled trials","volume":"7","author":"Spannella F","year":"2020","unstructured":"Spannella F, Giulietti F, Filipponi A, Sarzani R. Effect of sacubitril\/valsartan on renal function: a systematic review and meta-analysis of randomized controlled trials. ESC Heart Fail. 2020, 7:3487-96. 10.1002\/ehf2.13002","journal-title":"ESC Heart Fail"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.12659","article-title":"Sacubitril\/valsartan in patients with heart failure with reduced ejection fraction with end-stage of renal disease","volume":"7","author":"Lee S","year":"2020","unstructured":"Lee S, Oh J, Kim H, et al.. Sacubitril\/valsartan in patients with heart failure with reduced ejection fraction with end-stage of renal disease. ESC Heart Fail. 2020, 7:1125-9. 10.1002\/ehf2.12659","journal-title":"ESC Heart Fail"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1159\/000541939","article-title":"Angiotensin receptor-neprilysin inhibitor for chronic kidney disease: strategies for renal protection","volume":"49","author":"Hishida E","year":"2024","unstructured":"Hishida E, Nagata D. Angiotensin receptor-neprilysin inhibitor for chronic kidney disease: strategies for renal protection. Kidney Blood Press Res. 2024, 49:916-32. 10.1159\/000541939","journal-title":"Kidney Blood Press Res"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1812851","article-title":"Angiotensin-neprilysin inhibition in acute decompensated heart failure","volume":"380","author":"Velazquez EJ","year":"2019","unstructured":"Velazquez EJ, Morrow DA, DeVore AD, et al.. Angiotensin-neprilysin inhibition in acute decompensated heart failure. N Engl J Med. 2019, 380:539-48. 10.1056\/NEJMoa1812851","journal-title":"N Engl J Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/448944-use-of-angiotensin-receptor-neprilysin-inhibitors-arnis-in-high-output-heart-failure-in-a-young-hemodialysis-patient-synergistic-or-cumulative-effect","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T06:27:36Z","timestamp":1766557656000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/448944-use-of-angiotensin-receptor-neprilysin-inhibitors-arnis-in-high-output-heart-failure-in-a-young-hemodialysis-patient-synergistic-or-cumulative-effect"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,23]]},"references-count":16,"URL":"https:\/\/doi.org\/10.7759\/cureus.99973","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12,23]]}}}