{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T01:41:08Z","timestamp":1777340468099,"version":"3.51.4"},"reference-count":0,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2001,5,1]],"date-time":"2001-05-01T00:00:00Z","timestamp":988675200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2001,5]]},"abstract":"<jats:p>To develop a noninvasive method for treatment of uterine fibroid tumors using high\u2010intensity focused ultrasound. Optimal high\u2010intensity focused ultrasound treatment would be dependent on quantitative information about ultrasonic tissue characteristics.<\/jats:p><jats:p>Ultrasonic attenuation and the sound speed of fresh human fibroid tumors and myometrium were measured as a function of frequency (1\u20103 MHz) by using a pulse transmission technique before and after in vitro high\u2010intensity focused ultrasound treatment (3.5 MHz at an intensity of 2,000 W\/cm2).<\/jats:p><jats:p>The ranges of the attenuation coefficients, before and after high\u2010intensity focused ultrasound treatment, were 0.9 to 2.2 and 1.8 to 3.9 dB\/cm2, respectively, for fibroid tumors and 0.5 to 1.6 and 1.7 to 3.3 dB\/cm2, respectively, for myometrium. Although the sound speed appeared to be independent of frequency (1,611 to 1,616 m\/s at 1 to 3 MHz) in both types of tissues, a slight increase of approximately 4 to 14 m\/s was observed after high\u2010intensity focused ultrasound treatment.<\/jats:p><jats:p>The results of this study represent our first reported values of the attenuation coefficient and sound speed in fibroid tumors and myometrium before and after high\u2010intensity focused ultrasound treatment.<\/jats:p>","DOI":"10.7863\/jum.2001.20.5.473","type":"journal-article","created":{"date-parts":[[2017,1,10]],"date-time":"2017-01-10T21:47:22Z","timestamp":1484084842000},"page":"473-480","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Attenuation coefficient and sound speed in human myometrium and uterine fibroid tumors."],"prefix":"10.7863","volume":"20","author":[{"given":"A","family":"Keshavarzi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S","family":"Vaezy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P J","family":"Kaczkowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Keilman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E Y","family":"Chi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V Y","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,5]]},"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.7863%2Fjum.2001.20.5.473","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.7863\/jum.2001.20.5.473","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T16:58:15Z","timestamp":1700413095000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.7863\/jum.2001.20.5.473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,5]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,5]]}},"alternative-id":["10.7863\/jum.2001.20.5.473"],"URL":"https:\/\/doi.org\/10.7863\/jum.2001.20.5.473","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,5]]},"assertion":[{"value":"2001-05-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}