{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,29]],"date-time":"2025-03-29T16:32:17Z","timestamp":1743265937800},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2002,1]]},"abstract":"<jats:p><jats:bold><jats:italic>Objective<\/jats:italic><\/jats:bold>. To evaluate the therapeutic effectiveness of percutaneous radio frequency ablation of small (\u22643\u2010cm) hepatocellular carcinoma with a LeVeen needle electrode. <jats:bold><jats:italic>Methods<\/jats:italic><\/jats:bold>. Thirty patients (mean age, 65.7 years) with 32 hepatocellular carcinomas (range, 1.2\u20133.0 cm; mean, 2.3 \u00b1 0.5 cm) underwent percutaneous radio frequency ablation to the center of the hepatocellular carcinoma after expansion of the inner needles. The manufacturer's recommended radio frequency ablation protocol was used. Posttreatment contrast\u2010enhanced color Doppler sonography, contrast\u2010enhanced computed tomography, and fine\u2010needle biopsy were performed to assess the radio frequency ablation\u2013induced coagulated necrosis. <jats:bold><jats:italic>Results<\/jats:italic><\/jats:bold>. Severe intratreatment pain made us abort radio frequency ablation in 2 patients. Complete tumor necrosis was achieved in 1 treatment session with 1 needle electrode insertion in 28 (93.4 %) of 30 nodules (28 patients). We found no residual focus on both color Doppler sonography and computed tomography after any of the sessions. In follow\u2010ups ranging from 3 to 15 months (mean, 8.4 months), no local recurrence was found in cases with complete tumor ablation. <jats:bold><jats:italic>Conclusions<\/jats:italic><\/jats:bold>. Radio frequency ablation with the LeVeen needle electrode was effective, obtaining complete coagulated necrosis with a safety margin when used for the treatment of small hepatocellular carcinomas.<\/jats:p>","DOI":"10.7863\/jum.2002.21.1.67","type":"journal-article","created":{"date-parts":[[2017,1,10]],"date-time":"2017-01-10T17:59:14Z","timestamp":1484071154000},"page":"67-76","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Small Hepatocellular 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