{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:41:49Z","timestamp":1792179709249,"version":"4.4.0"},"reference-count":20,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2002,10,1]],"date-time":"2002-10-01T00:00:00Z","timestamp":1033430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2002,10]]},"abstract":"<jats:p><jats:bold><jats:italic>Objective.<\/jats:italic><\/jats:bold> To quantify the normal distance between the insertion of the medial leaflets of the mitral valve and tricuspid valve in the fetal heart. This mitral valve\u2013tricuspid valve distance was compared with the distance from known cases of Ebstein anomaly. <jats:bold><jats:italic>Methods.<\/jats:italic><\/jats:bold> An apical 4\u2010chamber view was obtained at end diastole in fetuses between 18 and 41 weeks' gestation. Calipers were placed parallel to the ventricular septum, with 1 caliper on the medial insertion of the mitral valve and a second caliper on the medial insertion of the tricuspid valve. The distance recorded was plotted against gestational age. Statistical analysis was performed by descriptive and linear regression techniques. <jats:bold><jats:italic>Results.<\/jats:italic><\/jats:bold> One hundred forty\u2010five fetuses were studied. The mean \u00b1 SD mitral valve\u2013tricuspid valve distance in the second trimester was 2.8 \u00b1 0.9 mm with a range of 1.2 to 5.0 mm; in the third trimester it was 4.6 \u00b1 1.1 mm with a range of 2.2 to 6.9 mm. Regression analysis showed that with each 1\u2010week increase in gestational age, there was an increase of 0.15 mm in separation between the medial leaflets of the mitral valve and tricuspid valve (\u03b2 = 0.15 \u00b1 0.011). <jats:bold><jats:italic>Conclusions.<\/jats:italic><\/jats:bold> A positive correlation between mitral valve\u2013tricuspid valve distance and advancing gestational age was found. The reference range described allows for the identification of a fetal heart with normal variation in the mitral valve\u2013tricuspid valve distance. Further downward displacement of the medial tricuspid cusp suggests the possibility of Ebstein anomaly.<\/jats:p>","DOI":"10.7863\/jum.2002.21.10.1099","type":"journal-article","created":{"date-parts":[[2017,1,10]],"date-time":"2017-01-10T18:54:53Z","timestamp":1484074493000},"page":"1099-1104","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["The Normal Offset of the Tricuspid Septal Leaflet in the Fetus"],"prefix":"10.7863","volume":"21","author":[{"given":"Ivana M.","family":"Vettraino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raywin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine H.","family":"Comstock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,10]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Bianchi DW Crombleholme TM D'Alton ME. Ebstein anomaly. In: Bianchi DW Crombleholme TM D'Alton ME (eds). Fetology: Diagnosis and Management of the Fetal Patient. 1st ed. New York NY: McGraw-Hill; 2000:377\u2013381."},{"key":"e_1_2_6_3_1","unstructured":"Sharland G. Tricuspid valve abnormalities. In: Allan L Hornberger LK Sharland G (eds). Textbook of Fetal Echocardiography. 1st ed. 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