{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T14:14:51Z","timestamp":1774361691791,"version":"3.50.1"},"reference-count":12,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2002,8,1]],"date-time":"2002-08-01T00:00:00Z","timestamp":1028160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2002,8]]},"abstract":"<jats:p><jats:bold><jats:italic>Objective<\/jats:italic><\/jats:bold>. To describe the sonographic findings of sirenomelia during the first trimester on both two\u2010dimensional sonography with color Doppler imaging and three\u2010dimensional sonography. <jats:bold><jats:italic>Methods<\/jats:italic><\/jats:bold>. Two cases of sirenomelia in primiparous patients with histories of infertility are described. The diagnosis was made on the basis of two\u2010dimensional sonography, and three\u2010dimensional sonography was used to further characterize the findings. <jats:bold><jats:italic>Results<\/jats:italic><\/jats:bold>. Both fetuses had size\u2010date discrepancies, increased nuchal translucency, large intra\u2010abdominal vessels, and 2\u2010vessel umbilical cords. Both pregnancies were terminated by dilation and curettage after the patients viewed the three\u2010dimensional pictures of the fetuses. <jats:bold><jats:italic>Conclusions<\/jats:italic><\/jats:bold>. During the first trimester of pregnancy, rare and lethal anomalies can be diagnosed with a high degree of confidence if a thorough, age\u2010dependant anatomic survey of the fetus is performed.<\/jats:p>","DOI":"10.7863\/jum.2002.21.8.915","type":"journal-article","created":{"date-parts":[[2017,1,10]],"date-time":"2017-01-10T00:04:30Z","timestamp":1484006670000},"page":"915-920","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":43,"title":["Sirenomelia Sequence"],"prefix":"10.7863","volume":"21","author":[{"given":"Ana","family":"Monteagudo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Mayberry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrei","family":"Rebarber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Paidas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilan E.","family":"Timor-Tritsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,8]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(13)90470-1"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002470050355"},{"key":"e_1_2_4_4_1","unstructured":"Jones KL. Sirenomelia sequence. In: Jones KL (ed). Smith's Recognizable Patterns of Human Malformation. 5th ed. Philadelphia PA: WB Saunders Co; 1997."},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1970150211"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/5.1.82"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2001.00426.x"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000053929"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1972.tb15799.x"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(88)80033-4"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.1870200403"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(93)90282-N"},{"key":"e_1_2_4_13_1","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1542\/peds.78.3.451","volume":"78","year":"1986","journal-title":"Pediatrics"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.7863%2Fjum.2002.21.8.915","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.7863\/jum.2002.21.8.915","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T15:01:18Z","timestamp":1700319678000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.7863\/jum.2002.21.8.915"}},"subtitle":["First\u2010Trimester Diagnosis With Both Two\u2010 and Three\u2010dimensional Sonography"],"short-title":[],"issued":{"date-parts":[[2002,8]]},"references-count":12,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2002,8]]}},"alternative-id":["10.7863\/jum.2002.21.8.915"],"URL":"https:\/\/doi.org\/10.7863\/jum.2002.21.8.915","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,8]]},"assertion":[{"value":"2002-03-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2002-05-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2002-08-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}