{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:17:01Z","timestamp":1762867021874},"reference-count":29,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2003,11,1]],"date-time":"2003-11-01T00:00:00Z","timestamp":1067644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2003,11]]},"abstract":"<jats:p><jats:bold><jats:italic>Objective<\/jats:italic><\/jats:bold>. This study was performed to compare endometrial biopsy and sonohysterography for evaluation of the endometrium in tamoxifen\u2010treated women. <jats:bold><jats:italic>Methods<\/jats:italic><\/jats:bold>. Medical records were retrospectively reviewed to identify 51 consecutive tamoxifen\u2010treated women who had sonohysterography and correlative endometrial biopsy for evaluation of postmenopausal bleeding or thickened endometrium of greater than 8 mm. Endometrial biopsy and sonohysterographic results were compared in all women, and for 27 (53%) women who had hysteroscopy with dilation and curettage, endometrial biopsy and sonohysterographic findings also were compared with surgical pathologic findings. <jats:bold><jats:italic>Results<\/jats:italic><\/jats:bold>. Thirty\u2010two (63%) of 51 sonohysterograms revealed endometrial polyps; 4 (8%) showed endometrium of greater than 5 mm; 14 (27%) showed endometrium of less than 5 mm; and 1 (2%) was inadequate. Endometrial biopsy findings were benign endometrium in 42 (82%), polyps in 4 (8%), and insufficient samples in 5 (10%). Among the adequate sonohysterograms, 64% (32 of 50) resulted in a diagnosis of polyps (95% confidence interval, 49%\u201377%) whereas the corresponding proportion for endometrial biopsy was 9% (4 of 46; 95% confidence interval, 2%\u201321%). For the group with hysteroscopy, 24 (92%) of 26 polyps were confirmed histopathologically; 1 polyp had complex hyperplasia. Polyps were present in 23 (89%) of 26 women with benign endometrium or insufficient samples by endometrial biopsy, and only 1 confirmed polyp was identified by endometrial biopsy. The sensitivity of sonohysterography for diagnosis of endometrial polyps (100%) was significantly higher than for endometrial biopsy (4%; <jats:italic>P<\/jats:italic> &lt; .01). <jats:bold><jats:italic>Conclusions<\/jats:italic><\/jats:bold>. In tamoxifen\u2010treated women, sonohysterography provides a significant improvement in sensitivity for diagnosis of endometrial polyps compared with endometrial biopsy.<\/jats:p>","DOI":"10.7863\/jum.2003.22.11.1173","type":"journal-article","created":{"date-parts":[[2017,1,9]],"date-time":"2017-01-09T17:04:26Z","timestamp":1483981466000},"page":"1173-1179","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Sonohysterography Compared With Endometrial Biopsy for Evaluation of the Endometrium in Tamoxifen\u2010Treated Women"],"prefix":"10.7863","volume":"22","author":[{"given":"Lucy E.","family":"Hann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cathleen 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