{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T11:30:36Z","timestamp":1769167836066,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2011,12,1]],"date-time":"2011-12-01T00:00:00Z","timestamp":1322697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2011,12]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The purpose of this study was to investigate the sensitivity and diagnostic value of convex probe endobronchial sonographically guided transbronchial needle aspiration (EBUS\u2010TBNA) in the diagnosis of granulomatous mediastinal lymphadenitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients clinically and radiologically suspected to have granulomatous mediastinal disease and followed in our clinic between October 2008 and July 2010 were included. Convex probe EBUS with local anesthesia and under conscious sedation and EBUS\u2010TBNA from hilar and mediastinal lymph nodes were performed after physical examination, chest radiography, computed tomography of the thorax, and routine biochemical analysis. Detection of noncaseating\/caseating granulomas was accepted as sufficient for diagnosis of sarcoidosis\/tuberculosis in the presence of clinical and radiologic findings. For patients whose EBUS\u2010TBNA results were nondiagnostic, a definitive diagnosis was reached by invasive procedures. The sensitivity of EBUS\u2010TBNA in the diagnosis of granulomatous lymphadenitis and diagnostic accuracy in granulomatous hilar\/mediastinal lymphadenopathies was calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seventy\u2010two patients were included in study (20 male and 52 female; mean age \u00b1 SD, 46.22 \u00b1 13.94 years). In 72 cases, 121 lymph node aspirations were performed. The average lymph node short axis was 1.96 cm. With EBUS\u2010TBNA among the 72 cases, 35 were diagnosed as sarcoidosis and 16 as tuberculous lymphadenitis. A definitive diagnosis could not be reached with EBUS\u2010TBNA in 21 cases. As a result, 9 of these EBUS\u2010TBNA\u2013negative cases were diagnosed as reactive lymphadenitis, 9 as sarcoidosis, and 3 as tuberculosis by invasive procedures. The sensitivity values of EBUS\u2010TBNA for diagnosis of sarcoidosis, tuberculosis, and granulomatous diseases were 79.5%, 84.2%, and 80.9%, respectively. The diagnostic accuracy of EBUS\u2010TBNA for granulomatous diseases was 83.3%. No major complications occurred.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In the diagnosis of granulomatous lymphadenitis, EBUS\u2010TBNA, with high sensitivity and a minimum complication rate, is an alternative to mediastinoscopy.<\/jats:p><\/jats:sec>","DOI":"10.7863\/jum.2011.30.12.1683","type":"journal-article","created":{"date-parts":[[2017,1,9]],"date-time":"2017-01-09T12:36:47Z","timestamp":1483965407000},"page":"1683-1689","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Sensitivity of Convex Probe Endobronchial Sonographically Guided Transbronchial Needle Aspiration in the Diagnosis of Granulomatous Mediastinal Lymphadenitis"],"prefix":"10.7863","volume":"30","author":[{"given":"Benan","family":"\u00c7a\u011flayan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Banu","family":"Salep\u00e7i","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Fidan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nesrin","family":"K\u0131ral","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sevda \u015eener","family":"C\u00f6mert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilek","family":"Yavuzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Recep","family":"Demirhan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fcl\u015fen","family":"Sara\u00e7","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2011,12]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"2363","volume-title":"General Thoracic Surgery","author":"Olak J","year":"2009"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.1.122"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-2768"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-1735"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-0998"},{"key":"e_1_2_7_7_1","first-page":"149","article-title":"ATS\/ERS\/WASOG statement on sarcoidosis: American Thoracic Society\/European Respiratory Society\/World Association of Sarcoidosis and other Granulomatous Disorders","volume":"16","author":"Hunninghake GW","year":"1999","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.111.6.1718"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00028706"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199704243361706"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200411-1560OC"},{"key":"e_1_2_7_12_1","doi-asserted-by":"crossref","first-page":"443","DOI":"10.3390\/medicina46070063","article-title":"Sarcoidosis: moving to the new standard of diagnosis?","volume":"46","author":"Miliauskas S","year":"2010","journal-title":"Medicina (Kaunas)"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(99)70059-0"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1980.122.5.721"},{"key":"e_1_2_7_15_1","first-page":"217","article-title":"Combining transbronchial aspiration with endobronchial and transbronchial biopsy in sarcoidosis","volume":"54","author":"Bila\u00e7ero\u011flu S","year":"1999","journal-title":"Monaldi Arch Chest Dis"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-0601"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.125.1.322"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.112.1.251"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.299.5.540"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2009.07.013"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.1.259"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1183\/09059180.00002910"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2011.01933.x"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.6.2126"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.11.011"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.106.3.709"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/000348948909800412"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.7863%2Fjum.2011.30.12.1683","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.7863\/jum.2011.30.12.1683","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T12:12:18Z","timestamp":1700482338000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.7863\/jum.2011.30.12.1683"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,12]]},"references-count":26,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2011,12]]}},"alternative-id":["10.7863\/jum.2011.30.12.1683"],"URL":"https:\/\/doi.org\/10.7863\/jum.2011.30.12.1683","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"value":"0278-4297","type":"print"},{"value":"1550-9613","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,12]]},"assertion":[{"value":"2011-04-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-07-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-12-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}