{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T20:55:11Z","timestamp":1740171311983,"version":"3.37.3"},"reference-count":23,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001864","name":"Latvian Ministry of Education and Science","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001864","id-type":"DOI","asserted-by":"crossref"}]},{"name":"European Structural Fund"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:sec><jats:title>Objectives<\/jats:title><jats:p>The purpose of this study was to determine whether a low splenic artery pulsatility index (PI) and reduced flow through the left portal vein are involved in redistribution of fetal growth restriction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Forty\u2010two women with prenatally diagnosed intrauterine growth restriction of singleton fetuses were included. The next pregnant woman with an appropriately growing fetus, matched for gestational age, was selected as a control. Blood flow velocities were measured in the splenic artery and left portal vein. Obstetric and perinatal information was obtained from standardized medical records.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The blood flow through the left portal vein was significantly reduced compared with the controls (<jats:italic>P<\/jats:italic> &lt; .0001). Placental impairment in fetal growth restriction was clearly linked to a decreased splenic artery PI (<jats:italic>P<\/jats:italic> = .0004). In growth\u2010restricted fetuses with reduced left portal vein flow and a splenic artery PI below the 5th percentile, perinatal mortality, a low 5\u2010minute Apgar score, and neonatal metabolic acidosis were observed significantly more often (<jats:italic>P<\/jats:italic> = .04, .01, and .004; <jats:italic>P<\/jats:italic> = .03, .03, and .006, respectively).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Reduced blood flow through the left portal vein and low resistance in the splenic artery can be found in growth\u2010restricted fetuses with adverse neonatal outcomes.<\/jats:p><\/jats:sec>","DOI":"10.7863\/jum.2012.31.2.223","type":"journal-article","created":{"date-parts":[[2017,1,9]],"date-time":"2017-01-09T22:14:25Z","timestamp":1484000065000},"page":"223-229","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Adaptive Changes in the Splenic Artery and Left Portal Vein in Fetal Growth Restriction"],"prefix":"10.7863","volume":"31","author":[{"given":"Natalija","family":"Vedmedovska","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dace","family":"Rezeberga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uldis","family":"Teibe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jana","family":"Zodzika","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilbert G. G.","family":"Donders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,2]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(00)90000-6"},{"volume-title":"The Investigation and Management of the Small-for-Gestational-Age Foetus","year":"2002","author":"Royal College of Obstetricians and Gynaecologists","key":"e_1_2_7_3_1"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7211116"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.2006.02256.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2337\/db08-0558"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1117"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.709717"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000253215.79121.75"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2003.11.018"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.2832"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000015505.24187.FA"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc07-0281"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(97)70489-7"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016340903214924"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e3181a29077"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.2.e35"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2005.24.4.425"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5146"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.6145"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2004.09.019"},{"key":"e_1_2_7_22_1","first-page":"62","author":"Regents of the University of California","year":"2004","journal-title":"Intensive Care Nursery House Staff Manuals"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1515\/jpm.2010.041"},{"key":"e_1_2_7_24_1","first-page":"151","article-title":"Fetal hepatic artery blood flow velocimetry in normal and high-risk pregnancies","volume":"6","author":"Dubiel M","year":"2001","journal-title":"Prenat Neonat Med"}],"container-title":["Journal of Ultrasound in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.7863%2Fjum.2012.31.2.223","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.7863\/jum.2012.31.2.223","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T04:52:28Z","timestamp":1700542348000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.7863\/jum.2012.31.2.223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["10.7863\/jum.2012.31.2.223"],"URL":"https:\/\/doi.org\/10.7863\/jum.2012.31.2.223","archive":["Portico"],"relation":{},"ISSN":["0278-4297","1550-9613"],"issn-type":[{"type":"print","value":"0278-4297"},{"type":"electronic","value":"1550-9613"}],"subject":[],"published":{"date-parts":[[2012,2]]},"assertion":[{"value":"2011-03-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2011-08-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-02-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}