{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T06:00:35Z","timestamp":1787032835199,"version":"build-2736575974"},"reference-count":22,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Ultrasound Medicine"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess intracranial structure volumes by 3\u2010dimensional (3D) sonography in fetuses with growth restriction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We conducted a prospective cross\u2010sectional case\u2010control study involving 59 fetuses with growth restriction (38 fetuses with estimated weight &lt;3rd percentile and 21 fetuses with estimated weight between 3rd and 10th percentiles, according to Hadlock et al [\n                      <jats:italic>Radiology<\/jats:italic>\n                      1984; 150:535\u2013540]) and 54 controls between 24 and 34 weeks' gestation. The following fetal intracranial structure volumes were assessed: cerebellum, brain, and frontal region. The volume was assessed by 3D sonography using the extended imaging virtual organ computer\u2010aided analysis method with 10 sequential planes. Analysis of variance was used to compare fetal groups. The intraclass correlation coefficient was used to assess intraobserver and interobserver reproducibility.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Statistical significance between the brain, frontal region, and cerebellar volumes and a relationship between the frontal region and the brain in fetuses with estimated weights below the 3rd percentile and controls were observed (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001;\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001; and\n                      <jats:italic>P<\/jats:italic>\n                      = .002; and\n                      <jats:italic>P<\/jats:italic>\n                      = .008, respectively). Good intraobserver and interobserver reproducibility was observed for the fetal brain, frontal region, and cerebellar volumes, with intraclass correlation coefficients of 0.998, 0.997, 0.997, 0.999, 0.997, and 0.998, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The intracranial structure volumes assessed by 3D sonography using the extended imaging virtual organ computer\u2010aided analysis method were reduced in fetuses with growth restriction (estimated weight &lt;3rd percentile).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.7863\/ultra.34.8.1397","type":"journal-article","created":{"date-parts":[[2015,7,23]],"date-time":"2015-07-23T17:43:37Z","timestamp":1437673417000},"page":"1397-1405","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Assessment of Intracranial Structure Volumes in Fetuses With Growth Restriction by 3\u2010Dimensional Sonography Using the Extended Imaging Virtual Organ Computer\u2010Aided Analysis Method"],"prefix":"10.1002","volume":"34","author":[{"given":"Ana Carolina Rabachini","family":"Caetano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Cristina Perez","family":"Zamarian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward Araujo","family":"J\u00fanior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael Oliveira","family":"Cavalcante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane","family":"Simioni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina Pacheco","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliam Cristine","family":"Rolo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio Fernandes","family":"Moron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano Marcondes 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