{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T06:58:22Z","timestamp":1770274702400,"version":"3.49.0"},"reference-count":16,"publisher":"The Korean Audiological Society","issue":"1","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002468","name":"Dong-A University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002468","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["ejao.org"],"crossmark-restriction":true},"short-container-title":["J Audiol Otol"],"published-print":{"date-parts":[[2022,1,10]]},"abstract":"<jats:p>Background and Objectives: To examine the maturational status of the auditory cortex in adults with cochlear implants (CIs) using the latencies of the P1, N1, and P2 components of cortical auditory-evoked potentials (CAEPs). Subjects and Methods: A total of 25 adults with CIs and 25 age-matched, normal-hearing control subjects participated in this study. Specifically, patients with CIs were divided into three groups depending on their age of deafness onset: Group A comprised patients with prelingual deafness who had received CI during early childhood (n=7), Group B comprised patients with early childhood-onset, progressive deafness who had received CI during childhood (n=6), and Group C comprised patients with adult-onset deafness (n=12). The P1, N1, and P2 latencies of their CAEPs were then compared between CI patients and normal-hearing subjects. Results: All participants showed clear CAEP responses. P1 and N1 latencies in Group A and Group C patients were significantly longer than those in the control group. Meanwhile, Group B patients had significantly longer N1 and P2 latencies, as compared with those in the control group. Conclusions: Patients with prelingual deafness and those with early-childhood onset, progressive deafness who received CI developed primary and higher-order auditory areas postoperatively when they became adults. However, their auditory cortex maturational statuses seemed to be worse than that of normal-hearing individuals. Furthermore, adult patients with late-onset deafness might experience degenerative auditory cortex changes during the auditory deprivation period between deafness onset and cochlear implantation.<\/jats:p>","DOI":"10.7874\/jao.2021.00339","type":"journal-article","created":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T01:11:15Z","timestamp":1635729075000},"page":"43-49","update-policy":"https:\/\/doi.org\/10.7874\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Cortical Auditory Evoked Potential in Adults With Cochlear Implants: A Comparison With Adults With Normal Hearing"],"prefix":"10.7874","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0196-2151","authenticated-orcid":true,"given":"Seong-Hyun","family":"Boo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5445-1638","authenticated-orcid":true,"given":"Sung Wook","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4621","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00003446-200212000-00004"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/35051653"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200207190-00030"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3109\/00016489709117760"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1055\/s-0035-1570334"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2011.09.004"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2005.11.010"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2004.12.010"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3766\/jaaa.16.8.5"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcomdis.2007.03.007"},{"key":"ref11","first-page":"1105","volume-title":"Cortical auditory evoked potential in aging: effects of stimulus intensity and noise","author":"Kim","year":"2012"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-018-5021-5"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.451"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1080\/14992020701524836"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/s0168-5597(97)00050-6"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2011.10.009"}],"container-title":["Journal of Audiology and Otology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/ejao.org\/upload\/pdf\/jao-2021-00339.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/ejao.org\/journal\/view.php?doi=10.7874\/jao.2021.00339","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/ejao.org\/upload\/pdf\/jao-2021-00339.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T00:37:47Z","timestamp":1641861467000},"score":1,"resource":{"primary":{"URL":"http:\/\/ejao.org\/journal\/view.php?doi=10.7874\/jao.2021.00339"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,10]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"URL":"https:\/\/doi.org\/10.7874\/jao.2021.00339","relation":{},"ISSN":["2384-1621","2384-1710"],"issn-type":[{"value":"2384-1621","type":"print"},{"value":"2384-1710","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,10]]},"assertion":[{"value":"2021-06-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-01","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-10","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}