{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T16:48:48Z","timestamp":1784047728074,"version":"3.55.0"},"reference-count":11,"publisher":"The Korean Audiological Society","issue":"3","license":[{"start":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T00:00:00Z","timestamp":1676505600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["ejao.org"],"crossmark-restriction":true},"short-container-title":["J Audiol Otol"],"published-print":{"date-parts":[[2023,7,10]]},"abstract":"<jats:p>Granulomatosis with polyangiitis (GPA) is a chronic and systematic autoimmune condition characterized by granuloma formation and necrotizing vasculitis of small to medium-sized vessels. GPA initially presents itself as respiratory and renal symptoms. Although temporal bone involvement is not uncommon, an otologic disorder is rarely the initial symptom. We present a case of a 36-year-old man who presented with unilateral ear pain, hearing loss, and facial palsy. After a series of diagnostics and temporal bone and chest imaging, he was diagnosed with GPA with multiorgan involvement. Cyclophosphamide and methylprednisolone relieved the patient\u2019s ear pain and partially improved his hearing, facial palsy, and overall clinical condition. Although uncommon, systemic GPA may cause initial otologic symptoms and should not be dismissed as a possible cause of an otologic disease resistant to standard therapy.<\/jats:p>","DOI":"10.7874\/jao.2022.00311","type":"journal-article","created":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T00:05:48Z","timestamp":1676505948000},"page":"161-167","update-policy":"https:\/\/doi.org\/10.7874\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A Case of Unilateral Otologic Symptoms as Initial Manifestations of Granulomatosis With Polyangiitis"],"prefix":"10.7874","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5917-5794","authenticated-orcid":true,"given":"Franko","family":"Batinovi\u0107","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2076-0512","authenticated-orcid":true,"given":"Marina Krni\u0107","family":"Martini\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0942-8092","authenticated-orcid":true,"given":"Merica Glavina","family":"Durdov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6480-4812","authenticated-orcid":true,"given":"Davor","family":"Sunara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4621","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2014.08.017"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1177\/0394632015617063"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200209000-00029"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2007.01.005"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.14.13864"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1177\/0194599820912025"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1177\/0003489418815517"},{"key":"ref8","first-page":"996","volume-title":"Otologic symptoms as initial manifestation of Wegener granulomatosis: diagnostic dilemma","author":"Wierzbicka","year":"2011"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1177\/2473974x18818791"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.7874\/jao.2016.20.1.55"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-022-03492-7"}],"container-title":["Journal of Audiology and Otology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/ejao.org\/upload\/pdf\/jao-2022-00311.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/ejao.org\/journal\/view.php?doi=10.7874\/jao.2022.00311","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/ejao.org\/upload\/pdf\/jao-2022-00311.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T07:00:21Z","timestamp":1689663621000},"score":1,"resource":{"primary":{"URL":"http:\/\/ejao.org\/journal\/view.php?doi=10.7874\/jao.2022.00311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,10]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,7]]}},"URL":"https:\/\/doi.org\/10.7874\/jao.2022.00311","relation":{},"ISSN":["2384-1621","2384-1710"],"issn-type":[{"value":"2384-1621","type":"print"},{"value":"2384-1710","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,10]]},"assertion":[{"value":"2022-07-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-16","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-10","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}