{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T11:10:05Z","timestamp":1780657805075,"version":"3.54.1"},"reference-count":31,"publisher":"The Korean Audiological Society","issue":"4","license":[{"start":{"date-parts":[[2024,10,10]],"date-time":"2024-10-10T00:00:00Z","timestamp":1728518400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2023-00253371"],"award-info":[{"award-number":["RS-2023-00253371"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Korea government"}],"content-domain":{"domain":["ejao.org"],"crossmark-restriction":true},"short-container-title":["J Audiol Otol"],"published-print":{"date-parts":[[2024,10,10]]},"abstract":"<jats:p>Background and Objectives: Cochlear schwannomas, which are categorized into intracochlear and intravestibulocochlear schwannomas (ICs and IVCs, respectively) are rare and may cause hearing loss (HL). The affected region is invariably correlated with tumor location, which can be detected on magnetic resonance imaging (MRI). We describe the cochleovestibular manifestations of ICs and IVCs. Subjects and Methods: The study included 31 patients with ICs or IVCs. Tumor extent and exact locations were delineated using MRI. Types of HL were subcategorized into the low-to-mid frequency (250 Hz to 1 kHz), mid-to-high frequency (&gt;1 kHz), and all-frequency (universal) HL groups. Results: The tumors involved the entire cochlear turn (two ICs) or extended beyond the cochleae (nine IVCs) in 11 patients, and 20 ICs were located in specific locations as follows: 14 in the basal, 3 in the middle, and 3 in the middle and apical turns. No patient showed tumor invasion of the internal auditory canal or middle ear. The pattern of HL usually reflects the location or extent of a tumor. We observed HL at all frequencies, at low-to-mid frequencies, and at mid-to-high frequencies in 13, 4, and 14 patients, respectively. Dizziness or tinnitus was observed in &gt;50% of patients. Surgical tumor removal was performed in 10 patients, and the remaining patients are undergoing annual monitoring. Conclusions: Cochlear schwannomas may be associated with HL, which may worsen over time and reflect tumor location. Therefore, these lesions should be considered in the differential diagnosis in patients who present with idiopathic, fluctuating, progressive or sudden HL.<\/jats:p>","DOI":"10.7874\/jao.2024.00115","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T02:10:07Z","timestamp":1729649407000},"page":"284-290","update-policy":"https:\/\/doi.org\/10.7874\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinico-Radiological Manifestations of Cochlear Schwannomas"],"prefix":"10.7874","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1366-6202","authenticated-orcid":true,"given":"Noor Dina","family":"Hashim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8656-1807","authenticated-orcid":true,"given":"Khairunnisak","family":"Misron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0382-7786","authenticated-orcid":true,"given":"Seo Jin","family":"Moon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2994-9602","authenticated-orcid":true,"given":"Hae Eun","family":"Noh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9978-4356","authenticated-orcid":true,"given":"Jinna","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3951-5074","authenticated-orcid":true,"given":"In Seok","family":"Moon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4621","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s002340050665"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200303000-00028"},{"key":"ref3","first-page":"1641","volume-title":"Clinical presentation of intralabyrinthine schwannomas: a multicenter study of 110 cases","author":"Dubernard","year":"2014"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.a2712"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200403000-00014"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23928"},{"key":"ref7","first-page":"944","volume-title":"Intralabyrinthine schwannomas: a case series with discussion of the diagnosis and management","author":"Bouchetembl\u00e9","year":"2013"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/bs.pbr.2021.01.023"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1053\/crad.2001.0834"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.2001.81.3.1305"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1667061"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1121\/1.388677"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199910000-00015"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/s0194-59980300610-7"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200101000-00017"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1177\/000348947908800207"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2019.00750"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00106-016-0198-7"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2018.05.007"},{"key":"ref20","first-page":"167","volume-title":"Intralabyrinthine schwannomas mimic cochleovestibular disease: symptoms from tumor mass effect in the labyrinth","author":"Slattery","year":"2015"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2020.623078"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s00106-020-00919-9"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3109\/00016489.2015.1015606"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26103"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2017(08)03"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200202000-00013"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2015.02.004"},{"key":"ref28","first-page":"549817","volume-title":"Cervical and ocular vestibular-evoked myogenic potentials in patients with intracochlear schwannomas","author":"Fr\u00f6hlich","year":"2020"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.a4922"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200405000-00021"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1097\/mao.0000000000002614"}],"container-title":["Journal of Audiology and Otology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/ejao.org\/upload\/pdf\/jao-2024-00115.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/ejao.org\/journal\/view.php?doi=10.7874\/jao.2024.00115","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/ejao.org\/upload\/pdf\/jao-2024-00115.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T08:05:53Z","timestamp":1730275553000},"score":1,"resource":{"primary":{"URL":"http:\/\/ejao.org\/journal\/view.php?doi=10.7874\/jao.2024.00115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,10]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,10]]}},"URL":"https:\/\/doi.org\/10.7874\/jao.2024.00115","relation":{},"ISSN":["2384-1621","2384-1710"],"issn-type":[{"value":"2384-1621","type":"print"},{"value":"2384-1710","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,10]]},"assertion":[{"value":"2024-02-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-10","order":2,"name":"published","label":"Published online","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-10","order":3,"name":"published","label":"Print publication","group":{"name":"publication_history","label":"Publication History"}}]}}