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ZhangYJ, Abe T, Tanaka T, et al. Phyllanemblinins A-F, new ellagitannins from <i>Phyllanthus emblica<\/i>. J Nat Prod. 2001;64:1527-32.","DOI":"10.1021\/np010370g"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Wang Y, Wang Q, Zhu Q, et al. Identification and characterization of acyclovir-resistant clinical HSV-1 isolates from children. J Clin Virol. 2011;52:107-12.","DOI":"10.1016\/j.jcv.2011.06.009"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Pei Y, Chen ZP, Ju HQ, et al. Autophagy is involved in anti-viral activity of pentagalloylglucose (PGG) against Herpes simplex virus type 1 infection in vitro. Biochem Biophys Res Commun. 2011;405:186-91.","DOI":"10.1016\/j.bbrc.2011.01.006"},{"key":"22","doi-asserted-by":"crossref","unstructured":"22. McElwee M, Beilstein F, Labetoulle M, et al. Dystonin\/BPAG1 promotes plus-end-directed transport of herpes simplex virus 1 capsids on microtubules during entry. 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