{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T14:02:59Z","timestamp":1789567379752,"version":"build-2803163510"},"reference-count":30,"publisher":"Editorial Committee of Japanese Journal of Infectious Diseases, National Institute of Infectious Dis","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Jpn J Infect Dis"],"published-print":{"date-parts":[[2019]]},"DOI":"10.7883\/yoken.jjid.2018.289","type":"journal-article","created":{"date-parts":[[2019,2,27]],"date-time":"2019-02-27T22:34:37Z","timestamp":1551306877000},"page":"228-236","source":"Crossref","is-referenced-by-count":16,"title":["Predominance of ST22-MRSA-IV Clone and Emergence of Clones for Methicillin-Resistant &lt;i&gt;Staphylococcus aureus&lt;\/i&gt; Clinical Isolates Collected from a Tertiary Teaching Hospital Over a Two-Year Period"],"prefix":"10.7883","volume":"72","author":[{"given":"Wen Kiong","family":"Niek","sequence":"first","affiliation":[{"name":"Department of Medical Microbiology, University of Malaya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cindy Shuan Ju","family":"Teh","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, University of Malaya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuryana","family":"Idris","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, University of Malaya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwai Lin","family":"Thong","sequence":"additional","affiliation":[{"name":"Institute of Biological Science, Faculty of Science, University of Malaya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sasheela","family":"Ponnampalavanar","sequence":"additional","affiliation":[{"name":"Department of Medicine, Faculty of Medicine, University of Malaya"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4631","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Song J-H, Hsueh P-R, Chung DR, et al. Spread of methicillin-resistant <i>Staphylococcus aureus<\/i> between the community and the hospitals in Asian countries: an ANSORP study. JAntimicrob Chemother. 2011;66:1061-9.","DOI":"10.1093\/jac\/dkr024"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Chen CJ, Huang YC. New epidemiology of <i>Staphylococcus aureus<\/i> infection in Asia. Clin Microbiol Infect. 2014;20:605-23.","DOI":"10.1111\/1469-0691.12705"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Stefani S, Chung DR, Lindsay JA, et al. Review: meticillin-resistant <i>Staphylococcus aureus<\/i> (MRSA): global epidemiology and harmonisation of typing methods. Int J Antimicrob Agents. 2012;39:273-82.","DOI":"10.1016\/j.ijantimicag.2011.09.030"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Rohani MY, Raudzah A, Lau MG, et al. Susceptibility pattern of <i>Staphylococcus aureus<\/i> isolated in Malaysian hospitals. Int J Antimicrob Agents. 2000;13:209-13.","DOI":"10.1016\/S0924-8579(99)00129-6"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Ahmad N, Ruzan IN, Abd Ghani MK, et al. Characteristics of community- and hospital-acquired meticillin-resistant <i>Staphylococcus aureus<\/i> strains carrying SCCmec type IV isolated in Malaysia. J Med Microbiol. 2009;58:1213-8.","DOI":"10.1099\/jmm.0.011353-0"},{"key":"6","unstructured":"6. Matthew TGH, Feil EJ, Lindsay JA, et al. Complete genomes of two clinical <i>Staphylococcus aureus<\/i> strains: evidence for the rapid evolution of virulence and drug resistance. Proc Natl Acad Sci U S A. 2004:9786-91."},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements (IWG-SCC). Classification of Staphylococcal cassette chromosome<i>mec<\/i>(SCC<i>mec<\/i>): guidelines for reporting novel SCC<i>mec<\/i> elements. Antimicrob Agents Chemother. 2009;53:4961-7.","DOI":"10.1128\/AAC.00579-09"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Enright MC, Day NP, Davies CE, et al. Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of <i>Staphylococcus aureus<\/i>. J Clin Microbiol. 2000;38:1008-15.","DOI":"10.1128\/JCM.38.3.1008-1015.2000"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. David MZ, Daum RS. Community-associated methicillin-resistant <i>Staphylococcus aureus<\/i>: epidemiology and clinical consequences of an emerging epidemic. Clin Microbiol Rev. 2010;23:616-87.","DOI":"10.1128\/CMR.00081-09"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Lim KT, Hanifah YA, Yusof MY, et al. Temporal changes in the genotypes of methicillin-resistant <i>Staphylococcus aureus<\/i> strains isolated from a tertiary Malaysian hospital based on MLST, spa, and <i>mec<\/i>-associated dru typing. Diagn Microbiol Infect Dis. 2012;74:106-12.","DOI":"10.1016\/j.diagmicrobio.2012.05.033"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Ghaznavi-Rad E, Nor Shamsudin M, Sekawi Z, et al. Predominance and emergence of clones of hospital-acquired methicillin-resistant <i>Staphylococcus aureus<\/i> in Malaysia. J Clin Microbiol. 2010;48:867-72.","DOI":"10.1128\/JCM.01112-09"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Milheirico C, Oliveira DC, de Lencastre H. Multiplex PCR strategy for subtyping the staphylococcal cassette chromosome <i>mec<\/i> type IV in methicillin-resistant <i>Staphylococcus aureus<\/i>: &apos;SCC<i>mec<\/i> IV multiplex&apos;. J Antimicrob Chemother. 2007;60:42-8.","DOI":"10.1093\/jac\/dkm112"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Hisata K, Kuwahara-Arai K, Yamanoto M, et al. Dissemination of methicillin-resistant staphylococci among healthy Japanese children. J Clin Microbiol. 2005;43:3364-72.","DOI":"10.1128\/JCM.43.7.3364-3372.2005"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Lina G, Boutite F, Tristan A, et al. Bacterial competition for human nasal cavity colonization: role of Staphylococcal <i>agr<\/i> alleles. Appl Environ Microbiol. 2003;69:18-23.","DOI":"10.1128\/AEM.69.1.18-23.2003"},{"key":"15","doi-asserted-by":"crossref","unstructured":"15. Jarraud S, Mougel C, Thioulouse J, et al. Relationships between <i>Staphylococcus aureus<\/i> genetic background, virulence factors, <i>agr<\/i> groups (alleles), and human disease. Infect Immun. 2002;70:631-41.","DOI":"10.1128\/IAI.70.2.631-641.2002"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Lina G, Pi\u00e9mont Y, Godail-Gamot F, et al. Involvement of Panton-Valentine leukocidin-producing <i>Staphylococcus aureus<\/i> in primary skin infections and pneumonia. Clin Infect Dis. 1999;29:1128-32.","DOI":"10.1086\/313461"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Tristan A, Ying L, Bes M, et al. Use of multiplex PCR to identify <i>Staphylococcus aureus<\/i> adhesins involved in human hematogenous infections. J Clin Microbiol. 2003;41:4465-7.","DOI":"10.1128\/JCM.41.9.4465-4467.2003"},{"key":"18","doi-asserted-by":"crossref","unstructured":"18. Yamaguchi T, Nishifuji K, Sasaki M, et al. Identification of the <i>Staphylococcus aureus<\/i> etd pathogenicity island which encodes a novel exfoliative toxin, ETD, and EDIN-B. Infect Immun. 2002;70:5835-45.","DOI":"10.1128\/IAI.70.10.5835-5845.2002"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Kumar JD, Negi YK, Gaur A, et al. Detection of virulence genes in <i>Staphylococcus aureus<\/i> isolated from paper currency. Int J Infect Dis. 2009;13:e450-5.","DOI":"10.1016\/j.ijid.2009.02.020"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Vasudevan P, Nair MK, Annamalai T, et al. Phenotypic and genotypic characterization of bovine mastitis isolates of <i>Staphylococcus aureus<\/i> for biofilm formation. Vet Microbiol. 2003;92:179-85.","DOI":"10.1016\/S0378-1135(02)00360-7"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Sit PS, Teh CS, Idris N, et al. Prevalence of methicillin-resistant <i>Staphylococcus aureus<\/i> (MRSA) infection and the molecular characteristics of MRSA bacteraemia over a two-year period in a tertiary teaching hospital in Malaysia. BMC Infect Dis. 2017;17:274.","DOI":"10.1186\/s12879-017-2384-y"},{"key":"22","unstructured":"22. Clinical and Laboratory Standards Institute (CLSI). Performance standards for antimicrobial susceptibility testing; 27th information supplement. Document M100. Wayne, PA: CLSI; 2017."},{"key":"23","doi-asserted-by":"crossref","unstructured":"23. Lim KT, Hanifah YA, Mohd Yusof MY, et al. Comparison of methicillin-resistant <i>Staphylococcus aureus<\/i> strains isolated in 2003 and 2008 with an emergence of multidrug resistant ST22: SCC<i>mec<\/i> IV clone in a tertiary hospital, Malaysia. J Microbiol Immunol Infect. 2013;46:224-33.","DOI":"10.1016\/j.jmii.2013.02.001"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Sun DD, Ma XX, Hu J, et al. Epidemiological and molecular characterization of community and hospital acquired <i>Staphylococcus aureus<\/i> strains prevailing in Shenyang, Northeastern China. Braz J Infect Dis. 2013;17:682-90.","DOI":"10.1016\/j.bjid.2013.02.007"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Valle DL Jr, Paclibare PA, Cabrera EC, et al. Molecular and phenotypic characterization of methicillin-resistant S<i>taphylococcus aureus<\/i> isolates from a tertiary hospital in the Philippines. Trop Med Health. 2016;44:3.","DOI":"10.1186\/s41182-016-0003-z"},{"key":"26","unstructured":"26. Lim KT, Hanifah YA, Mohd Yusof MY, et al. Investigation of toxin genes among methicillin-resistant <i>Staphylococcus aureus<\/i> strains isolated from a tertiary hospital in Malaysia. Tropical biomedicine. 2012;29:212-9."},{"key":"27","doi-asserted-by":"crossref","unstructured":"27. Hu DL, Omoe K, Inoue F, et al. Comparative prevalence of superantigenic toxin genes in meticillin-resistant and meticillin-susceptible <i>Staphylococcus aureus<\/i> isolates. J Med Microbiol. 2008;57:1106-12.","DOI":"10.1099\/jmm.0.2008\/002790-0"},{"key":"28","doi-asserted-by":"crossref","unstructured":"28. Sauer P, Sila J, Stosova T, et al. Prevalence of genes encoding extracellular virulence factors among meticillin-resistant <i>Staphylococcus aureus<\/i> isolates from the University Hospital, Olomouc, Czech Republic. J Med Microbiol. 2008;57:403-10.","DOI":"10.1099\/jmm.0.47413-0"},{"key":"29","doi-asserted-by":"crossref","unstructured":"29. Plata K, Rosato AE, Wegrzyn G. <i>Staphylococcus aureus<\/i> as an infectious agent: overview of biochemistry and molecular genetics of its pathogenicity. Acta Biochim Pol. 2009;56:597-612.","DOI":"10.18388\/abp.2009_2491"},{"key":"30","doi-asserted-by":"crossref","unstructured":"30. Sit PS, Teh CSJ, Idris N, et al. Methicillin-resistant <i>Staphylococcus aureus<\/i> (MRSA) bacteremia: correlations between clinical, phenotypic, genotypic characteristics and mortality in a tertiary teaching hospital in Malaysia. Infect Genet Evol. 2018;59:132-41.","DOI":"10.1016\/j.meegid.2018.01.031"}],"container-title":["Japanese Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/yoken\/72\/4\/72_JJID.2018.289\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,28]],"date-time":"2020-11-28T19:39:19Z","timestamp":1606592359000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/yoken\/72\/4\/72_JJID.2018.289\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.7883\/yoken.jjid.2018.289","relation":{},"ISSN":["1344-6304","1884-2836"],"issn-type":[{"value":"1344-6304","type":"print"},{"value":"1884-2836","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019]]}}}