{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T05:16:40Z","timestamp":1788585400044,"version":"build-2803163510"},"reference-count":15,"publisher":"Editorial Committee of Japanese Journal of Infectious Diseases, National Institute of Infectious Dis","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Jpn J Infect Dis"],"published-print":{"date-parts":[[2026,8,31]]},"DOI":"10.7883\/yoken.jjid.2025.285","type":"journal-article","created":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T22:10:17Z","timestamp":1788127817000},"source":"Crossref","is-referenced-by-count":0,"title":["Emergence of Human Parechovirus Type 5 Meningitis in Japan, 2025"],"prefix":"10.7883","author":[{"given":"Yushi","family":"Yamamoto","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Kobe City Nishi-Kobe Medical Center, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aya","family":"Iwata","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kobe City Nishi-Kobe Medical Center, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kousaku","family":"Matsubara","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kobe City Nishi-Kobe Medical Center, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keigo","family":"Hamahata","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kobe City Medical Center General Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junji","family":"Eguchi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Kobe City Medical Center West Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai","family":"Mori","sequence":"additional","affiliation":[{"name":"Health Research Department 2, Kobe Institute of Health, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryohei","family":"Nomoto","sequence":"additional","affiliation":[{"name":"Health Research Department 2, Kobe Institute of Health, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4631","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Sasidharan A, Harrison CJ, Selvarangan R. Diagnosis, management, and outcomes of parechovirus infections in infants: an overview. J Clin Microbiol. 2024;62:e0113923.","DOI":"10.1128\/jcm.01139-23"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Bozzola E, Barni S, Barone C, et al. Human parechovirus meningitis in children: state of the art. Ital J Pediatr. 2023;49:144","DOI":"10.1186\/s13052-023-01550-4"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Chamings A, Liew KC, Reid E, et al. An emerging human parechovirus type 5 causing sepsis-like illness in infants in Australia. Viruses. 2019;11:913.","DOI":"10.3390\/v11100913"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. George G, Restivo L, Jijon DF, et al. Emergence of a new pathogen: A retrospective study of HPeV5 central nervous system disease in Alberta, Canada. Viruses. 2024;16:1684.","DOI":"10.3390\/v16111684"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Dhar D, Sasidharan A, VanDonge KE, et al. Emergence of parechovirus-A5 central nervous system infections in children from Kansas City, Missouri, USA. J Clin Virol. 2025;180:105835.","DOI":"10.1016\/j.jcv.2025.105835"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Piralla A, Perniciaro S, Ossola S, et al. Human parechovirus type 5 neurological infection in a neonate with a favourable outcome: A case report. Int J Infect Dis. 2019;89:175-178.","DOI":"10.1016\/j.ijid.2019.10.006"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Bubba L, Broberg EK, Fischer TK, et al. Parechovirus A circulation and testing capacities in Europe, 2015-2021. Emerg Infect Dis. 2024;30:234-244.","DOI":"10.3201\/eid3002.230647"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Ohnishi A, Kikuchi M, Nakata S, et al. Genetic analysis of human parechovirus type 5 isolated from children in Sapporo, Japan in the summer of 2018. J Infect Chemother. 2022;28:714-717.","DOI":"10.1016\/j.jiac.2022.01.016"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Cremer J, Morley U, Pas S, et al. Highly sensitive parechovirus CODEHOP PCR amplification of the complete VP1 gene for typing directly from clinical specimens and correct typing based on phylogenetic clustering. J Med Microbiol. 2019;68:1194-1203.","DOI":"10.1099\/jmm.0.000974"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Harvala H, Robertson I, McWilliam Leitch EC, et al. Epidemiology and clinical associations of human parechovirus respiratory infections. J Clin Microbiol. 2008;46:3446-3453.","DOI":"10.1128\/JCM.01207-08"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Rembeck K, Elfving K, Churqui MP, et al. Clinical spectrum and epidemiology of human parechovirus infections in infants: A retrospective study in the Western part of Sweden. Open Forum Infect Dis. 2024;11:ofae268.","DOI":"10.1093\/ofid\/ofae268"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Cabrerizo M, Trallero G, Pena MJ, et al. Comparison of epidemiology and clinical characteristics of infections by human parechovirus vs. those by enterovirus during the first month of life. Eur J Pediatr. 2015;174:1511-1516.","DOI":"10.1007\/s00431-015-2566-9"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Harvala H, Calvert J, Van Nguyen D, et al. Comparison of diagnostic clinical samples and environmental sampling for enterovirus and parechovirus surveillance in Scotland, 2010-2012. Eurosurveillance. 2014;19:20772.","DOI":"10.2807\/1560-7917.ES2014.19.15.20772"},{"key":"14","doi-asserted-by":"crossref","unstructured":"14. Hara S, Kawada J, Kawano Y, et al. Hyperferritinemia in neonatal and infantile human parechovirus-3 infection in comparison with other infectious diseases. J Infect Chemother. 2014;20:15-19.","DOI":"10.1016\/j.jiac.2013.11.002"},{"key":"15","unstructured":"15. Wada S, Kasai M, Matsui Y, et al. Clinical utility of FilmArray Meningitis\/Encephalitis Panel in an epidemic of human parechovirus central nervous system infection. J Pediatr Infect Dis Immunol. 2024;36:233-242 (in Japanese with English abstract)."}],"container-title":["Japanese Journal of Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/yoken\/advpub\/0\/advpub_JJID.2025.285\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T04:44:33Z","timestamp":1788583473000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/yoken\/advpub\/0\/advpub_JJID.2025.285\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,31]]},"references-count":15,"URL":"https:\/\/doi.org\/10.7883\/yoken.jjid.2025.285","relation":{},"ISSN":["1344-6304","1884-2836"],"issn-type":[{"value":"1344-6304","type":"print"},{"value":"1884-2836","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,31]]},"article-number":"JJID.2025.285"}}