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Cozzi R, Montini M, Attanasio R, Albizzi M, Lasio G, Lodrini S, Doneda P, Cortesi L & Pagani G (2006): Primary treatment of acromegaly with octreotide LAR: a long-term (up to nine years) prospective study of its efficacy in the control of disease activity and tumor shrinkage. J Clin Endocrinol Metab 91: 1397\u22121403","DOI":"10.1210\/jc.2005-2347"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Giustina A, Mazziotti G, Torri V, Spinello M, Floriani I & Melmed S (2012): Meta-analysis on the effects of octreotide on tumor mass in acromegaly. PLoS One 7: e36411","DOI":"10.1371\/journal.pone.0036411"},{"key":"7","unstructured":"7. Wang JW, Li Y, Mao ZG, Hu B, Jiang XB, Song BB, Wang X, Zhu YH & Wang HJ (2014): Clinical applications of somatostatin analogs for growth hormone-secreting pituitary adenomas. Patient Prefer Adherence 8: 43\u221251"},{"key":"8","unstructured":"8. Melmed S, Colao A, Barkan A <i>et al<\/i> (2009): Guidelines for acromegaly managemant: an update. 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