{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T06:01:19Z","timestamp":1787032879753,"version":"build-2736575974"},"reference-count":25,"publisher":"The University of Occupational and Environmental Health, Japan","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J UOEH"],"published-print":{"date-parts":[[2024,6,1]]},"DOI":"10.7888\/juoeh.46.221","type":"journal-article","created":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T18:14:51Z","timestamp":1717524891000},"page":"221-226","source":"Crossref","is-referenced-by-count":7,"title":["An Autopsy Case of Dextromethorphan Poisoning","\u30c7\u30ad\u30b9\u30c8\u30ed\u30e1\u30c8\u30eb\u30d5\u30a1\u30f3\u4e2d\u6bd2\u306e1\u5256\u691c\u4f8b"],"prefix":"10.7888","volume":"46","author":[{"given":"Toshiko","family":"TANAKA","sequence":"first","affiliation":[{"name":"Department of Forensic Medicine, School of Medicine, University of Occupational and Environmental Health, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"SATO","sequence":"additional","affiliation":[{"name":"Department of Forensic Medicine, School of Medicine, University of Occupational and Environmental Health, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"KIMURA","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Kitakyushu City Yahata Hospital, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentaro","family":"KASAI","sequence":"additional","affiliation":[{"name":"Department of Forensic Medicine, School of Medicine, University of Occupational and Environmental Health, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"UMEHARA","sequence":"additional","affiliation":[{"name":"Department of Forensic Medicine, School of Medicine, University of Occupational and Environmental Health, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"4637","reference":[{"key":"1","doi-asserted-by":"crossref","unstructured":"1. Logan BK, Goldfogel G, Hamilton R &amp; Kuhlman J (2009): Five deaths resulting from abuse of dextromethorphan sold over the internet. J Anal Toxicol 33 (2): 99\u2013103","DOI":"10.1093\/jat\/33.2.99"},{"key":"2","doi-asserted-by":"crossref","unstructured":"2. Brown GR, McLaughlin K &amp; Vaughn K (2018): Identifying and treating patients with synthetic psychoactive drug intoxication. Jaapa 31 (8): 1\u20135","DOI":"10.1097\/01.JAA.0000541487.41149.71"},{"key":"3","doi-asserted-by":"crossref","unstructured":"3. Burns JM &amp; Boyer EW (2013): Antitussives and substance abuse. Subst Abuse Rehabil 4: 75\u201382","DOI":"10.2147\/SAR.S36761"},{"key":"4","doi-asserted-by":"crossref","unstructured":"4. Mutschler J, Koopmann A, Grosshans M, Hermann D, Mann K &amp; Kiefer F (2010): Dextromethorphan withdrawal and dependence syndrome. Dtsch Arztebl Int 107 (30): 537\u2013540","DOI":"10.3238\/arztebl.2010.0537"},{"key":"5","doi-asserted-by":"crossref","unstructured":"5. Majlesi N, Lee DC &amp; Ali SS (2011): Dextromethorphan abuse masquerading as a recurrent seizure disorder. Pediatr Emerg Care 27 (3): 210\u2013211","DOI":"10.1097\/PEC.0b013e31820d8dc1"},{"key":"6","doi-asserted-by":"crossref","unstructured":"6. Xu J, Ou H, Sun P, Qin S &amp; Yuan TF (2021): Brief report: Predictors of relapse for patients with dextromethorphan dependence. Am J Addict 30 (2): 192\u2013194","DOI":"10.1111\/ajad.13114"},{"key":"7","doi-asserted-by":"crossref","unstructured":"7. Bertaso A, Musile G, Gottardo R, Seri C &amp; Tagliaro F (2015): Chiral analysis of methorphan in opiate-overdose related deaths by using capillary electrophoresis. J Chromatogr B Analyt Technol Biomed Life Sci 1000: 130\u2013135","DOI":"10.1016\/j.jchromb.2015.07.024"},{"key":"8","doi-asserted-by":"crossref","unstructured":"8. Yoo Y, Chung H, Kim E &amp; Kim M (1996): Fatal zipeprol and dextromethorphan poisonings in Korea. J Anal Toxicol 20 (3): 155\u2013158","DOI":"10.1093\/jat\/20.3.155"},{"key":"9","doi-asserted-by":"crossref","unstructured":"9. Shafi H, Imran M, Usman HF <i>et al<\/i> (2016): Deaths due to abuse of dextromethorphan sold over-the-counter in Pakistan. Egypt J Forensic Sci 6 (3): 280\u2013283","DOI":"10.1016\/j.ejfs.2015.07.002"},{"key":"10","doi-asserted-by":"crossref","unstructured":"10. Shimozawa S, Usuda D, Sasaki T <i>et al<\/i> (2023): High doses of dextromethorphan induced shock and convulsions in a 19-year-old female: A case report. World J Clin Cases 11 (16): 3870","DOI":"10.12998\/wjcc.v11.i16.3870"},{"key":"11","doi-asserted-by":"crossref","unstructured":"11. Ishida T, Kudo K, Inoue H, Tsuji A, Kojima T &amp; Ikeda N (2006): Rapid screening for and simultaneous semiquantitative analysis of thirty abused drugs in human urine samples using gas chromatography-mass spectrometry. J Anal Toxicol 30 (7): 468\u2013477","DOI":"10.1093\/jat\/30.7.468"},{"key":"12","doi-asserted-by":"crossref","unstructured":"12. Tanaka T, Yoshizumi S, Kasai K, Yoshida K &amp; Sato H (2021): Efficacy of DRIVEN-FLOW\u00ae M7-II, a new on-site drug screening kit in postmortem urine compared with Triage DOA\u00ae. Leg Med 48: 101804","DOI":"10.1016\/j.legalmed.2020.101804"},{"key":"13","doi-asserted-by":"crossref","unstructured":"13. Schulz M, Schmoldt A, Andresen-Streichert H &amp; Iwersen-Bergmann S (2020): Revisited: therapeutic and toxic blood concentrations of more than 1100 drugs and other xenobiotics. Crit Care 24: 1\u20134","DOI":"10.1186\/s13054-020-02915-5"},{"key":"14","unstructured":"14. Journey JD, Agrawal S &amp; Stern E (2024): Dextromethorphan toxicity. <i>In<\/i>: StatPearls. StatPearls Publishing, FL"},{"key":"15","unstructured":"15. Med Lett Drugs Ther (2018): Drugs for cough. Med Lett Drugs Ther. 60: 206\u2013208"},{"key":"16","doi-asserted-by":"crossref","unstructured":"16. Ahmed G, Saleem MD &amp; Naim H (2014): How many deaths before we put cough syrups behind the counter? Perspect Public Heal 134 (6): 309","DOI":"10.1177\/1757913914551914"},{"key":"17","doi-asserted-by":"crossref","unstructured":"17. Baldo BA (2018): Opioid analgesic drugs and serotonin toxicity (syndrome): mechanisms, animal models, and links to clinical effects. Arch Toxicol 92 (8): 2457\u20132473","DOI":"10.1007\/s00204-018-2244-6"},{"key":"18","unstructured":"18. Bruggeman C &amp; O\u2019Day CS (2024): Selective serotonin reuptake inhibitor toxicity. <i>In<\/i>: StatPearls. StatPearls Publishing, FL"},{"key":"19","doi-asserted-by":"crossref","unstructured":"19. Dy P, Arcega V, Ghali W &amp; Wolfe W (2017): Serotonin syndrome caused by drug to drug interaction between escitalopram and dextromethorphan. BMJ Case Rep 2017","DOI":"10.1136\/bcr-2017-221486"},{"key":"20","doi-asserted-by":"crossref","unstructured":"20. Anttila SA &amp; Leinonen EV (2001): A review of the pharmacological and clinical profile of mirtazapine. CNS Drug Rev 7 (3): 249\u2013264","DOI":"10.1111\/j.1527-3458.2001.tb00198.x"},{"key":"21","doi-asserted-by":"crossref","unstructured":"21. Jahng JW, Zhang TY, Lee S &amp; Kim DG (2001): Effects of dextromethorphan on nocturnal behavior and brain c-Fos expression in adolescent rats. Eur J Pharmacol 431 (1): 47\u201352","DOI":"10.1016\/S0014-2999(01)01409-1"},{"key":"22","unstructured":"22. Verslegers W, Van den Kerchove M, Crols R, De Potter W, Appel B &amp; Lowenthal A (1988): Methanol intoxication. Parkinsonism and decreased Met-enkephalin levels due to putaminal necrosis. Acta Neurol Belg 88 (3): 163\u2013171"},{"key":"23","unstructured":"23. Moral AR, Ayano\u011flu HO &amp; Erhan E (1997): Putaminal necrosis after methanol intoxication. Intensive Care Med 23 (2): 234\u2013235"},{"key":"24","doi-asserted-by":"crossref","unstructured":"24. Sasaki N, Ishida J, Kojima N <i>et al<\/i> (2008): A Case of Methanol Intoxication Suspected \u2018Top of the Basilar Syndrome\u2019. Nihon Kyukyu Igakukai Zasshi 19: 160\u2013167","DOI":"10.3893\/jjaam.19.160"},{"key":"25","doi-asserted-by":"crossref","unstructured":"25. Barceloux DG, Bond GR, Krenzelok EP, Cooper H &amp; Vale JA (2002): American Academy of Clinical Toxicology practice guidelines on the treatment of methanol poisoning. J Toxicol Clin Toxicol 40 (4): 415\u2013446","DOI":"10.1081\/CLT-120006745"}],"container-title":["Journal of UOEH"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/juoeh\/46\/2\/46_221\/_pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,7]],"date-time":"2024-09-07T00:30:24Z","timestamp":1725669024000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jstage.jst.go.jp\/article\/juoeh\/46\/2\/46_221\/_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,1]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.7888\/juoeh.46.221","relation":{},"ISSN":["0387-821X","2187-2864"],"issn-type":[{"value":"0387-821X","type":"print"},{"value":"2187-2864","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,1]]}}}