{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T19:40:04Z","timestamp":1751485204044,"version":"3.41.0"},"reference-count":12,"publisher":"International College of Surgeons","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013]]},"abstract":"<jats:title>Abstract<\/jats:title>\n        <jats:p>A 62-year-old man was referred to our hospital because of pain in the right upper quadrant. Laboratory tests revealed normal levels of tumor markers. Abdominal ultrasonography showed a hypoechoic mass of approximately 9 cm in diameter in the right lobe of the liver. Computed tomography revealed a low-density mass with peripheral enhancement in the posterior segment of the right lobe. Magnetic resonance imaging showed a low-intensity mass on T<jats:sub>1<\/jats:sub>-weighted images and a high-intensity mass on T<jats:sub>2<\/jats:sub>-weighted images. Abdominal angiography showed enhanced staining only at the periphery of the tumor. An open biopsy was performed and intraoperative examination of frozen sections indicated malignant lymphoma. The histopathologic diagnosis was malignant T-cell lymphoma. After combined chemotherapy, the tumor shrank to 4 cm in diameter. To our knowledge, only 15 cases of malignant T-cell lymphoma have been reported previously. Diagnosis is particularly challenging because this type of tumor has no distinctive imaging characteristics or signs or symptoms. This case emphasizes the need to include malignant T-cell lymphoma in the differential diagnosis and demonstrates the importance of open biopsy in patients with a suspected liver tumor.<\/jats:p>","DOI":"10.9738\/cc162.1","type":"journal-article","created":{"date-parts":[[2013,2,25]],"date-time":"2013-02-25T19:39:56Z","timestamp":1361821196000},"page":"13-18","source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic Value of Open Biopsy for Malignant T-Cell Lymphoma of the Liver"],"prefix":"10.9738","volume":"98","author":[{"given":"Akihisa","family":"Hojo","sequence":"first","affiliation":[{"name":"Departments ofDigestive Surgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisashi","family":"Nakayama","sequence":"additional","affiliation":[{"name":"Departments ofDigestive Surgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Aramaki","sequence":"additional","affiliation":[{"name":"Departments ofDigestive Surgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tokio","family":"Higaki","sequence":"additional","affiliation":[{"name":"Departments ofDigestive Surgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masamichi","family":"Moriguchi","sequence":"additional","affiliation":[{"name":"Departments ofDigestive Surgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiko","family":"Sugitani","sequence":"additional","affiliation":[{"name":"Pathology,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuhiro","family":"Miura","sequence":"additional","affiliation":[{"name":"Hematology and Rheumatology, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Takeuchi","sequence":"additional","affiliation":[{"name":"Hematology and Rheumatology, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryu","family":"Nishiyama","sequence":"additional","affiliation":[{"name":"Gastroenterology and Hepatology, Nihon University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuhiko","family":"Moriyama","sequence":"additional","affiliation":[{"name":"Gastroenterology and Hepatology, Nihon University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadatoshi","family":"Takayama","sequence":"additional","affiliation":[{"name":"Departments ofDigestive Surgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4721","reference":[{"issue":"12","key":"i0020-8868-98-1-13-b01","series-title":"Am J Gastroenterol","first-page":"2789","article-title":"Primary hepatic non-Hodgkin's lymphomas: case report and review of the literature","volume":"98","author":"Santos\n              ES ,","year":"2003","unstructured":"Santos\n              ES , \n            \n              Raez\n              LE , \n            \n              Salvatierra\n              J , \n            \n              Morgensztern\n              D , \n            \n              Shanmugan\n              N , \n            \n              Neff\n              GW . \n          \n          Primary hepatic non-Hodgkin's lymphomas: case report and review of the literature . 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Leg Med2011 ;13(4) :191 \u2013195"},{"issue":"4","key":"i0020-8868-98-1-13-b04","series-title":"Gastroenterology","first-page":"1230","article-title":"Reduced mortality rates following elective percutaneous liver biopsy","volume":"139","author":"West\n              J ,","year":"2010","unstructured":"West\n              J , \n            \n              Card\n              TR . \n          \n          Reduced mortality rates following elective percutaneous liver biopsy . Gastroenterology2010 ;139(4) :1230 \u20131237"},{"issue":"3","key":"i0020-8868-98-1-13-b05","series-title":"Crit Rev Oncol Hematol","first-page":"199","article-title":"Primary non-Hodgkin's lymphoma of the liver","volume":"53","author":"Noronha\n              V ,","year":"2005","unstructured":"Noronha\n              V , \n            \n              Shafi\n              NQ , \n            \n              Obando\n              JA , \n            \n              Kummar\n              S . \n          \n          Primary non-Hodgkin's lymphoma of the liver . Crit Rev Oncol Hematol2005 ;53(3) :199 \u2013207"},{"issue":"4","key":"i0020-8868-98-1-13-b06","series-title":"Hong Kong Med J","first-page":"288","article-title":"Primary hepatic peripheral T-cell lymphoma in a patient with chronic hepatitis B infection","volume":"15","author":"Leung\n              VK ,","year":"2009","unstructured":"Leung\n              VK , \n            \n              Lin\n              SY , \n            \n              Loke\n              TK , \n            \n              Chau\n              TN , \n            \n              Leung\n              CY , \n            \n              Fung\n              TP\n            \n            et al\n           . Primary hepatic peripheral T-cell lymphoma in a patient with chronic hepatitis B infection . Hong Kong Med J2009 ;15(4) :288 \u2013290"},{"issue":"12","key":"i0020-8868-98-1-13-b07","series-title":"Dig Dis Sci","first-page":"1632","article-title":"Primary lymphoma of the liver showing immunohistochemical evidence of T-cell origin: successful management by right trisegmentectomy","volume":"33","author":"Andreola\n              S ,","year":"1988","unstructured":"Andreola\n              S , \n            \n              Audisio\n              RA , \n            \n              Mazzaferro\n              V , \n            \n              Doci\n              R , \n            \n              Makowka\n              L , \n            \n              Gennari\n              L . \n          \n          Primary lymphoma of the liver showing immunohistochemical evidence of T-cell origin: successful management by right trisegmentectomy . Dig Dis Sci1988 ;33(12) :1632 \u20131636"},{"issue":"12","key":"i0020-8868-98-1-13-b08","series-title":"J Clin Pathol","first-page":"1007","article-title":"Primary lymphoma of the liver: clinical and pathological features of 10 patients","volume":"43","author":"Anthony\n              PP ,","year":"1990","unstructured":"Anthony\n              PP , \n            \n              Sarsfield\n              P , \n            \n              Clarke\n              T . \n          \n          Primary lymphoma of the liver: clinical and pathological features of 10 patients . J Clin Pathol1990 ;43(12) :1007 \u20131013"},{"issue":"8","key":"i0020-8868-98-1-13-b09","series-title":"Cancer","first-page":"1336","article-title":"Aggressive primary hepatic lymphoma in Chinese patients: presentation, pathologic features, and outcome","volume":"76","author":"Lei\n              KI ,","year":"1995","unstructured":"Lei\n              KI , \n            \n              Chow\n              JH , \n            \n              Johnson\n              PJ . \n          \n          Aggressive primary hepatic lymphoma in Chinese patients: presentation, pathologic features, and outcome . Cancer1995 ;76(8) :1336 \u20131343"},{"issue":"2","key":"i0020-8868-98-1-13-b10","series-title":"J Korean Med Sci","first-page":"240","article-title":"A case report of primary T-cell lymphoma of the liver","volume":"15","author":"Kim\n              HS ,","year":"2000","unstructured":"Kim\n              HS , \n            \n              Ko\n              YH , \n            \n              Ree\n              HJ . \n          \n          A case report of primary T-cell lymphoma of the liver . J Korean Med Sci2000 ;15(2) :240 \u2013242"},{"issue":"11","key":"i0020-8868-98-1-13-b11","series-title":"Can J Gastroenterol","first-page":"955","article-title":"Primary lymphoma of the liver: a case report and review","volume":"14","author":"Schweiger\n              F ,","year":"2000","unstructured":"Schweiger\n              F , \n            \n              Shinder\n              R , \n            \n              Rubin\n              S . \n          \n          Primary lymphoma of the liver: a case report and review . Can J Gastroenterol2000 ;14(11) :955 \u2013957"},{"key":"i0020-8868-98-1-13-b12","article-title":"AJCC Cancer Staging Handbook. 7th ed","author":"Edge\n              SB ,","year":"2010","unstructured":"Edge\n              SB , \n            \n              Byrd\n              DR , \n            \n              Compton\n              CC , \n            \n              Fritz\n              AG , \n            \n              Greene\n              FL , \n            et al\n           , eds. AJCC Cancer Staging Handbook. 7th ed . New York : Springer-Verlag ; 2010 ."}],"container-title":["International Surgery"],"original-title":[],"link":[{"URL":"https:\/\/international-surgery.kglmeridian.com\/view\/journals\/insu\/98\/1\/article-p13.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/meridian.allenpress.com\/international-surgery\/article-pdf\/98\/1\/13\/2214410\/cc162_1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/international-surgery.kglmeridian.com\/downloadpdf\/journals\/insu\/98\/1\/article-p13.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/international-surgery.kglmeridian.com\/downloadpdf\/journals\/insu\/98\/1\/article-p13.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T18:59:27Z","timestamp":1751482767000},"score":1,"resource":{"primary":{"URL":"https:\/\/international-surgery.kglmeridian.com\/view\/journals\/insu\/98\/1\/article-p13.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013]]},"references-count":12,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.9738\/cc162.1","relation":{},"ISSN":["0020-8868","2520-2456"],"issn-type":[{"type":"print","value":"0020-8868"},{"type":"electronic","value":"2520-2456"}],"subject":[],"published":{"date-parts":[[2013]]}}}