{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T04:17:53Z","timestamp":1751516273572,"version":"3.41.0"},"reference-count":10,"publisher":"International College of Surgeons","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n        <jats:p>We report a case of multiple primary hepatic cancers exhibiting different pathologic features coexisting in a patient with chronic hepatitis C. Computed tomography showed 2 tumors in segment 8, 20\u00a0mm (S8-A) and 5\u00a0mm (S8-B) in diameter, and a 10-mm tumor in segment 6 (S6). Based on the images, the S8-A lesion was diagnosed as cholangiocellular carcinoma or combined hepatocellular carcinoma and cholangiocarcinoma (combined HCC-CC). The other 2 tumors were diagnosed as HCC. The patient underwent partial resections of segments 6 and 8. We found 2 more tumors (S8-C was 6\u00a0mm in diameter and S8-D was 4\u00a0mm) in the resected segment 8 specimen. Histopathologic examination revealed that the S8-A and S8-C tumors were combined HCC-CC, the S8-B and S6 lesions were scirrhous HCC, and the S8-D tumor was an early HCC. This is a very rare case in which different hepatic cancers with multiple pathologic features coexisted.<\/jats:p>","DOI":"10.9738\/cc72.1","type":"journal-article","created":{"date-parts":[[2012,10,25]],"date-time":"2012-10-25T15:57:41Z","timestamp":1351180661000},"page":"17-22","source":"Crossref","is-referenced-by-count":2,"title":["Primary Hepatic Cancers With Multiple Pathologic Features in a Patient With Hepatitis C: Report of a Case"],"prefix":"10.9738","volume":"97","author":[{"given":"Go","family":"Oshima","sequence":"first","affiliation":[{"name":"Department of Surgery, Keio University, School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Shinoda","sequence":"additional","affiliation":[{"name":"Department of Surgery, Keio University, School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minoru","family":"Tanabe","sequence":"additional","affiliation":[{"name":"Department of Surgery, Keio University, School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohei","family":"Masugi","sequence":"additional","affiliation":[{"name":"Department of Pathology, Keio University, School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihisa","family":"Ueno","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Keio University, School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiminori","family":"Takano","sequence":"additional","affiliation":[{"name":"Department of Surgery, Keio University, School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minoru","family":"Kitago","sequence":"additional","affiliation":[{"name":"Department of Surgery, Keio University, School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osamu","family":"Itano","sequence":"additional","affiliation":[{"name":"Department of Surgery, Keio University, School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeyuki","family":"Kawachi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Keio University, School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Ohara","sequence":"additional","affiliation":[{"name":"Department of Pathology, Keio University, School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaya","family":"Oda","sequence":"additional","affiliation":[{"name":"Internal Medicine, Sanno Hospital, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiro","family":"Tanimoto","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Radiology, Keio University, School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michiie","family":"Sakamaoto","sequence":"additional","affiliation":[{"name":"Department of Pathology, Keio University, School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuko","family":"Kitagawa","sequence":"additional","affiliation":[{"name":"Department of Surgery, Keio University, School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"4721","reference":[{"issue":"5","key":"i0020-8868-97-1-17-Liver1","series-title":"Acta Hepatol Jpn","first-page":"288","article-title":"Survey and follow-up study of primary liver cancer in Japan. 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